Patient-perceived effectiveness and impact on quality of life of solifenacin in combination with an α-blocker in men with overactive bladder in Sweden: a non-interventional study

Treating male lower urinary tract symptoms (LUTS) by targeting the prostate would have limited effect on overactive bladder (OAB) symptoms. This study assessed perceived symptoms and quality of life (QoL) of male patients with OAB treated with an α-blocker plus solifenacin in daily clinical practice. Male patients aged ≥40 years were included after the decision was made to initiate treatment with an α-blocker for LUTS plus solifenacin for OAB symptoms. The primary endpoint was change in patient perception of bladder condition (PPBC) questionnaire score over 6?months. Other assessments included the OAB-questionnaire short form (OAB-q SF) and International Prostate Symptom Score (IPSS). Interpretation of the study data was hindered by not meeting the enrollment target and a high dropout rate. In 36 evaluable patients, mean (SD) PPBC score improved from 4.3 (0.93) at baseline (“moderate” to “severe” problems) to 3.5 (1.06) at month 6 (“minor” to “moderate” problems). OAB-q SF scores and total IPSS also improved. In this patient population, treatment with solifenacin and an α-blocker resulted in improvements in male patient perception of their LUTS and QoL, although the results should be interpreted with caution due to the low number of patients with complete data.     

Ethnic entrepreneurship and the question of agency: the role of different forms of capital,and the relevance of social class

The literature on ethnic entrepreneurship has focused on structural factors, group characteristics or a combination of both when explaining the entry and/or success of different ethnic groups in/to self-employment. While the active involvement of individuals has often been noted, agency has been under-theorised, and frequently conflated with what are considered as ‘cultural’ factors. This article explores the question of agency in ethnic entrepreneurship by looking at how entrepreneurs access and mobilise different kinds of resources. Using a forms-of-capital approach, the article draws on qualitative data from the U.K. and Spain, and looks at how entrepreneurs mobilise cultural, social and economic resources in structural contexts that include constraining as well as enabling features. Our findings show that the entrepreneurs are active agents who play an important role in shaping ethnic businesses. However, their agency varies significantly depending on the extent to which entrepreneurs have access to different kinds of resources, which is closely linked to their socioeconomic position. The article contributes to the literature through its direct engagement with the question of agency in ethnic entrepreneurship, and by highlighting the relevance of social class in entrepreneurial processes.     

Mothering,Fathering, and Externalizing Behavior in Toddler Boys

This study examined the effects of reported maternal and paternal support, psychological control, and spanking on externalizing behavior of toddler boys. Questionnaires were administered to both parents of 104 two‐parent families with a 3‐year‐old son. Both maternal and paternal psychological control was related to boys' externalizing behavior. Interaction effects were found, in that the association between maternal spanking and boys' externalizing behavior was stronger when levels of maternal support were high. High levels of paternal support strengthened the association between maternal support and boys' externalizing behaviors. Results suggest that the associations between specific parenting dimensions and children's externalizing behavior need to be considered within the context of other parenting dimensions that are displayed within the family.     

Long-term changes in parenting and child behavior after the Home-Start family support program

Background

The intervention Home-Start is a wide spread program in a number of countries, among which the Netherlands. In Home-Start, trained volunteers visit families with young children in need of support once or twice a week to help them to deal with problems in family life and parenting. Little is known, however, about the effects of Home-Start. This study describes short-term and long term changes in families that participated in Home-Start.

Methods

Three groups of families with young children (at the start mean age 1 1/2 years) were followed over a period of four years. One of the groups of families participated in the Home-Start family support program in the first 6.6 months of this period. The two other groups were (1) a randomly selected community sample and (2) a group of families with elevated parenting stress and a need for support. Data were collected at the beginning of the study, (after median 1.4 months), directly after the intervention (median 6.6 months) and at two follow-up occasions (respectively, median 12.5 and 49.2 months after the first measurement). At the last measurement, data were available for 33, 45 and 34 families respectively.

Results

Multilevel analysis showed more positive changes in parental wellbeing, competence and behavior (more consistent behavior and less rejection) during the intervention period in the Home-Start group than in the two other groups. At the three year follow up, the Home-Start group showed, compared to the other groups, more improvements in parenting (more responsiveness), but also diminished child externalizing and internalizing behavior problems (less oppositional defiant behavior, affective problems and anxiety problems).

Conclusions

Home-Start seems a promising family support intervention that deserves to be studied more extensively.