湿蒸汽两相流流量及干度的双参数测量研究

本文采用孔板及均速管组合形式,对汽-水两相流的流量及干度的双参数测量进行了实验研究。实验结果表明,这种测量方法可以满足高干度湿蒸汽测量的要求,具有很好的工业适用性。     

接触式低温固定中样品内部传热过程的分析

建立了用于电子显微镜生物样品制备的接触式低温固定法中的传热过程模型,并求得了一维常物性条件下的精确解。讨论了样品内部冷却速率的一些变化规律及其与样品初始温度和固化温度的关系,为实际的低温固定操作提供了理论指导。     

Assessing Effects on Long-term Survival after Early Termination of Randomized Trials

In this paper we present an approach to using historical control data to augment information from a randomized controlled clinical trial, when it is not possible to continue the control regimen to obtain the most reliable and valid assessment of long term treatment effects. Using an adjustment procedure to the historical control data, we investigate a method of estimating the long term survival function for the clinical trial control group and for evaluating the long term treatment effect. The suggested method is simple to interpret, and particularly motivated in clinical trial settings when ethical considerations preclude the long term follow-up of placebo controls. A simulation study reveals that the bias in parameter estimates that arises in the setting of group sequential monitoring will be attenuated when long term historical control information is used in the proposed manner. Data from the first and second National Wilms' Tumor studies are used to illustrate the method.     

光学湍流中的滞后現象

本文以延时反馈光电混合型光学双稳装置为例,在先前他人工作的基础上,给出了下列光学湍流中的新的结果:在适当选择系统增益情况下,原有双稳区可能分裂为三个,以及延时算子的高阶影响,特别是在实验上首次观察到了分岔点的滞后现象.     

知识经济与广州城市性质功能定位

本文认为,面对２１ 世纪和知识经济时代,广州城市性质与功能的定位必然产生变化。广州要发展,必须发展知识经济,确立由４ 个系统组成的广州知识经济创新体系,确立教育和科技产业成为知识经济产业的一个支柱部门,成为广州发展的主导因素之一。为此,广州城市性质与功能应该定位为华南地区、东南亚地区的教育科技城和以知识经济产业为主体的多功能的中心城市     

注重素质培养,实现教育实习的目的

面对实习学校设备参差不齐,指导教师素质有高有低,实习学生来源、民族、性别比例不均的状况,我校教育实习相应地采取了城乡结合式、基地式等多种形式.在实习中,通过准备、实习、总结三个阶段,加强学生教风、教态、仪表、行为、着装、语言和板书的专门素质教育,以期达到教育实习的目的.     

An efficient sequential design of clinical trials

We propose an efficient group sequential monitoring rule for clinical trials. At each interim analysis both efficacy and futility are evaluated through a specified loss structure together with the predicted power. The proposed design is robust to a wide range of priors, and achieves the specified power with a saving of sample size compared to existing adaptive designs. A method is also proposed to obtain a reduced-bias estimator of treatment difference for the proposed design. The new approaches hold great potential for efficiently selecting a more effective treatment in comparative trials. Operating characteristics are evaluated and compared with other group sequential designs in empirical studies. An example is provided to illustrate the application of the method.     

国际上非基准年购买力平价推算方法评价

 全球国际比较项目大约每隔5年或6年调查一次,有关国际组织应用总量外推法、分类项目外推法、基期滚动法和简缩信息法等方法推算非基准年的PPP数据,以便取得完整的连续时间序列。本文对国际上常用的各种非基准年PPP推算方法和结果作详细分析、评价。     

Maximum likelihood estimation of the bimodal failure rate for censored and tied observations

DIMITROV, RACHEV and YAKOVLEV ( 1985 ) have obtained the isotonic maximum likelihood estimator for the bimodal failure rate function. The authors considered only the complete failure time data. The generalization of this estimator for the case of censored and tied observations is now proposed.     

Modeling of covariance structures of random effects and random errors in linear mixed models

Abstract

In this paper, we discuss how to model the mean and covariancestructures in linear mixed models (LMMs) simultaneously. We propose a data-driven method to modelcovariance structures of the random effects and random errors in the LMMs. Parameter estimation in the mean and covariances is considered by using EM algorithm, and standard errors of the parameter estimates are calculated through Louis’ (1982 Louis, T.A. (1982). Finding observed information using the EM algorithm. J. Royal Stat. Soc. B 44:98–130. [Google Scholar]) information principle. Kenward’s (1987 Kenward, M.G. (1987). A method for comparing profiles of repeated measurements. Appl. Stat. 36:296–308.[Crossref], [Web of Science ®] , [Google Scholar]) cattle data sets are analyzed for illustration,and comparison to the literature work is made through simulation studies. Our numerical analysis confirms the superiority of the proposed method to existing approaches in terms of Akaike information criterion.