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There is currently no well-accepted standard method for evaluation of developmental toxicity data. This paper presents one approach to the evaluation of developmental toxicity data. We initially identify some pertinent factors that influence the interpretation of animal data and summarize the literature pertaining to these factors. Such factors include the quality and quantity of data and the relationship between maternal and developmental toxicity. We proceed with a discussion of quantitative assessment of data and propose schemes for qualitative and quantitative developmental hazard assessments.  相似文献   
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This paper presents a view of research and development absorptive capacity from a Māori perspective. The assessment is part of a case study of a longitudinal programme – Science for Technological Innovation: Kia kotahi mai – Te Ao Putaiao me te Ao Hanagarau that aims to increase Aotearoa New Zealand’s capacity to use sci-tech for economic benefit. The paper finds that while Aotearoa New Zealand’s macro policy and meso institutional levels have become more responsive to Māori research and development demands, at the micro level of the individual or the firm there are still constraints given the small numbers of Māori in science, technology, engineering and mathematics. In response to this, a novel model of Māori sci-tech capacity is under development that considers not only research and development technical capacities, but also the human and relational capacities required to accelerate absorptive capacity to respond to Māori social and economic aspirations.  相似文献   
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VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations - Despite the increased social significance currently attached to national identity, little is known about how national...  相似文献   
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Sexual minority men report higher psychological distress than heterosexual men, including depression and anxiety. Research suggests that these health disparities may be due to the heightened stressors that gay, lesbian, and bisexual individuals experience. Some of these stressors occur early on in life, such as childhood abuse and bullying, and may include stressors that are topically related to sexual minority status, such as anti-gay bullying and teasing for gender nonconformity to masculine gender norms. We tested a structural equation model on the association between negative childhood experiences and adult psychological distress among 304 gay and bisexual men. The model fit the data well, and demonstrated an indirect effect of negative childhood experiences on adult psychological distress via dysfunctional thoughts toward oneself. The results integrate the childhood abuse and anti-gay bullying victimization literatures by showing that both forms of adverse childhood experiences are associated with adult psychological distress. The findings suggest the benefit of treatments to reduce negative, dysfunctional thoughts among gay and bisexual men who have experienced adverse childhood events.  相似文献   
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The Hand Arm Risk Assessment Method (HARM 1.0) has been developed for occupational health officers to perform risk assessments of developing arm, neck or shoulder pain during hand arm tasks. The tool can also help in finding solutions for risk reduction and estimating their effect on the risk level. In this paper the status of affairs and the practical application of HARM is described. The usage of HARM is explained and illustrated with the risk assessment of a specific hand arm task. In addition, the experiences with the application of HARM by a stone factory in The Netherlands are described.  相似文献   
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Older adult physical activity (PA) levels obtained from the International Physical Activity Questionnaire-Short Form (IPAQ) and accelerometry (ACC) were compared. Mean difference scores between accumulated or bout ACC PA and the IPAQ were computed. Spearman rank-order correlations were used to assess relations between time spent in PA measured from ACC and self-reported form of the IPAQ, and percentage agreement across measures was used to classify meeting or not meeting PA recommendations. The IPAQ significantly underestimated sitting and overestimated time spent in almost all PA intensities. Group associations across measures revealed significant relations in walking, total PA, and sitting for the whole group (r = .29-.36, p < .05). Significant relationships between bout ACC and IPAQ walking (r = .28-.39, p < .05) were found. There was 40-46% agreement between measures for meeting PA recommendations. The IPAQ appears not to be a good indicator of individual older adult PA behavior but is better suited for larger population-based samples.  相似文献   
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我国政府已把动漫作为重要发展的文化产业,中国动漫业成长空间十分广阔。但目前还存在动漫产业受到国外的冲击,中国的传统文化在动漫产业中被边缘化等问题。重温经典,我国动漫产业很早就开始了对传统文化元素的挖掘。当前的中国动漫业应从中国传统文化中汲取营养,创造性地把中国传统文化运用到动漫产业中来,这是我国动漫产业发展的一条现实之路。  相似文献   
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Therapists from Australia, New Zealand, the US, Germany and the UK discuss the relationship between systemic and narrative therapy.  相似文献   
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