Informed consent for research on stored blood and tissue samples: a survey of institutional review board practices

Numerous position papers have outlined informed consent recommendations for the collection, storage, and future use of biological samples; however, there currently is no consensus regarding what kinds of information should be included in consent forms. This study aimed to determine whether institutional review boards (IRBs) vary in their informed consent requirements for research on stored biological samples, and whether any variation observed could be correlated to factors such as volume of work, IRB members' familiarity with ethical issues in genetic research, and IRBs' use of either of two policy guidelines as resources. A brief survey was mailed to all IRB chairpersons on a mailing list obtained from the Office for Human Research Protections. Survey questions included whether consent forms for the collection of biological samples for future use address each of six provisions recommended in current guidelines and position statements, and whether IRBs used the Office for Protection from Research Risks' 1993 Protecting Human Research Subjects: Institutional Review Board Guidebook, chapter 5 (hereinafter IRB Guidebook) or the National Bioethics Advisory Commission's 1999 Research Involving Human Biological Materials: Ethical Issues and Policy Guidance, Volume I (hereinafter Report) in their deliberations. Despite a low response rate (22%, 427 respondents), results indicate that IRB practices vary substantially. The degree to which the provisions were included in consent forms was found to correlate positively with IRBs that review a greater volume of protocols annually, those that use the National Bioethics Advisory Commission Report in their deliberations, and those that draw on both the Report and the IRB Guidebook.     

Care for Kids — Do We? A Psychological Study of State Wards in New South Wales

An investigation of children entering State wardship revealed a common background of poverty, mobility of domicile, neglect and deprivation together with physical abuse. There were high levels of parental loss and parental psychiatric illness and criminality. While of average intelligence, the children were educationally retarded and emotionally disturbed with depression and hostility the main symptoms. They perceived their environment as violent and aggressive and themselves as deprived or experiencing loss. Most clung to idealized parental figures and denied the reality of their present situation. On discharge from the receiving centre only four children were fostered and the rest continued in care.     

The Role of Child Emotionality in Child Behavior and Maternal Instruction on Planning Tasks

This study explored the relation of children's emotional functioning to children's behavior during individual planning and mother's and children's behaviors during joint planning. Participants were 118 mothers and their second‐grade children. Mothers rated children on their emotional intensity and children rated themselves on their use of emotion regulation strategies. Children and mother–child dyads were videotaped during planning tasks and independent observers rated their behavior. Child emotional intensity was directly related to children being less engaged in the task and to an emphasis in maternal instruction on regulatory behaviors. Some types of emotion regulation strategies modified these relations. Findings suggest that child emotionality may play an important role in the early school years in children's opportunities to learn during social‐cognitive activity.     

Tempered Regrets Under Total Ignorance

Several decision rules, including the minimax regret rule, have been posited to suggest optimizing strategies for an individual when neither objective nor subjective probabilities can be associated to the various states of the world. These all share the shortcoming of focusing only on extreme outcomes. This paper suggests an alternative approach of tempered regrets which may more closely replicate the decision process of individuals in those situations in which avoiding the worst outcome tempers the loss from not achieving the best outcome. The assumption of total ignorance of the probabilities associated with the various states is maintained. Applications and illustrations from standard neoclassical theory are discussed.     

Abusive Supervision and Well-Being of Filipino Migrant Workers in Macau: Consequences for Self-Esteem and Heritage Culture Detachment

Abusive supervision in the workplace has been shown to have important direct consequence in work and work relationship, and also indirect consequences to workers’ well-being and relationships outside work. Consequences of abusive supervision have not been studied among migrant workers whose status in the host country of work is dependent on maintaining the work contract. This study investigates abusive supervision in 247 Filipino migrant workers in Macau, who hold temporary work contracts and work visas to engage in various low-skilled work (e.g., domestic helper, security guard, etc.). The study tests a model representing the indirect consequences of abusive supervision on the self-esteem and acculturation orientation of migrant workers, in particular, on the tendency to reject their heritage culture in their attempt to acculturate in the host country. Mediation analysis indicated that abusive supervisory perceptions led to lower self-esteem (b = ?.19), which in turn relates to tendency to reject their heritage culture as part of acculturation (b = ?.45) [indirect effect = .08, 90 % CI .04, .15]. The rejection of heritage culture is interpreted as a coping response to the negative indirect consequences of abusive supervision perceptions that may be partly attributed to being a migrant Filipino worker. The results are discussed in terms of how the acculturation of migrant workers reflects aspects of their well-being that may be adversely affected by vocational-related stress in the host country.     

Implementing a Multidimensional Poverty Measure Using Mixed Methods and a Participatory Framework

Recently, there have been advances in the development of multidimensional poverty measures. Work is needed however on how to implement such measures. This paper deals with the process of selecting dimensions and setting weights in multidimensional poverty measurement using qualitative and quantitative methods in a participatory framework. We estimate the multidimensional poverty measures developed by Alkire and Foster for a particular group: persons with psychiatric diagnoses in the United States. To select relevant dimensions and their relative ordering, two discussion groups are convened: one consisting of persons with lived-experience expertise and the other consisting of people with mental health service provision or research expertise. Several methods are used to convert dimension rankings into weights. The selection and ordering of dimensions differed between the two discussion groups, as did the resulting poverty measures. For instance, the poverty headcount using the dimensions and weights of the ‘lived experience’ group ranged from 20.61 to 26.96% as compared to a range of 18.62–33.19% using those of the ‘provider/researcher’ group. One of the main results of this study is that the Alkire Foster method is sensitive to the selection of dimensions and the methods used to derive rankings and weights. It points toward the limitation of relying exclusively on small scale qualitative methods for the selection and ranking of dimensions. In addition, the participatory framework used in this study was found to be essential in interpreting results, in particular with respect to the limitations of the data set in measuring relevant dimensions.