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21.
Masami Hasegawa 《Researches on Population Ecology》1990,32(1):119-133
Summary The demography of the lizardEumeces okadae was studied for 4 years on Miyake-jima, in the Izu Islands, central Japan. Most males matured at 3 years of age with a mean
snout-vent length of 77.5 mm. Females matured at 3–4 years with a mean SVL of 77.8 mm, and reproduced biennially thereafter.
Growth continued after maturity with a decreasing rate. In females, annual growth was negligible in reproductive years, but
resumed markedly in non-reproductive years. Clutch size increased with SVL and was used to construct a fecundity schedule.
Population density (exclusive of hatchlings) was estimated to be ca. 4000 individuals/ha in August, an exceptionally high
density for lizards. Before introduction of the weasel onto Miyake-jima, low predation pressure had allowedE. okadae to maintain a high population density. Estimated annual survival rates were 36% for hatchlings, 56% for yearlings, 80% for
2-year-olds, 63% for adult males and 76% for adult females. The cohort generation time (6.95 years) was so long that theE. okadae population can be characterized by a combination of low natality and slow turnover. 相似文献
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Takahiro Hasegawa 《Pharmaceutical statistics》2014,13(2):128-135
In recent years, immunological science has evolved, and cancer vaccines are available for treating existing cancers. Because cancer vaccines require time to elicit an immune response, a delayed treatment effect is expected. Accordingly, the use of weighted log‐rank tests with the Fleming–Harrington class of weights is proposed for evaluation of survival endpoints. We present a method for calculating the sample size under assumption of a piecewise exponential distribution for the cancer vaccine group and an exponential distribution for the placebo group as the survival model. The impact of delayed effect timing on both the choice of the Fleming–Harrington's weights and the increment in the required number of events is discussed. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
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Takahiro Maeda Masanori Hasegawa Toshiyuki Ando Masashi Matsushima Kazuyuki Yuge 《The aging male》2016,19(2):111-116
We prospectively evaluated erectile function (EF) using the Sexual Health Inventory for Men (SHIM) and the erectile hardness score (EHS) as well as urinary statuses using the International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS) before and 3, 6, and 12 months after a daily treatment with 0.5?mg dutasteride (DUT). Significant improvements were observed in IPSS and OABSS in 98 patients with the DUT treatment, and the effects were similar between 28 patients with potency with baseline SHIM of 8 or greater and 70 severe erectile dysfunction (ED) patients at baseline. In the 28 patients with potency, significant decreases were observed in SHIM and EHS after 3, 6, and 12 months of the DUT treatment, with the severity of ED according to SHIM deteriorating in half of these patients after 12 months of the DUT treatment. Eighteen out of 28 patients (64.3%) with potency at baseline had awareness of the occurrence of ED before the DUT treatment, were younger, and had higher SHIM and EHS just before the DUT treatment than their counterparts. Regular assessments of EF may be needed, especially in younger patients and those with higher levels of EF before the administration of DUT. 相似文献
25.
The effect of health insurance coverage on personal bankruptcy: evidence from the Medicaid expansion
Review of Economics of the Household - This paper investigates the effects of health insurance coverage among low-income people on personal bankruptcies at the county level and the state level,... 相似文献
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Jun'ichiro Iwahori Akio Yamamoto Hodaka Suzuki Takehisa Yamamoto Toshiyuki Tsutsui Keiko Motoyama Mikiko Sawada Tomoki Matsushita Atsushi Hasegawa Ken Osaka Hajime Toyofuku Fumiko Kasuga 《Risk analysis》2010,30(12):1817-1832
The aim of this study was to evaluate the effects of implemented control measures to reduce illness induced by Vibrio parahaemolyticus (V. parahaemolyticus) in horse mackerel (Trachurus japonicus), seafood that is commonly consumed raw in Japan. On the basis of currently available experimental and survey data, we constructed a quantitative risk model of V. parahaemolyticus in horse mackerel from harvest to consumption. In particular, the following factors were evaluated: bacterial growth at all stages, effects of washing the fish body and storage water, and bacterial transfer from the fish surface, gills, and intestine to fillets during preparation. New parameters of the beta‐Poisson dose‐response model were determined from all human feeding trials, some of which have been used for risk assessment by the U.S. Food and Drug Administration (USFDA). The probability of illness caused by V. parahaemolyticus was estimated using both the USFDA dose‐response parameters and our parameters for each selected pathway of scenario alternatives: washing whole fish at landing, storage in contaminated water, high temperature during transportation, and washing fish during preparation. The last scenario (washing fish during preparation) was the most effective for reducing the risk of illness by about a factor of 10 compared to no washing at this stage. Risk of illness increased by 50% by exposure to increased temperature during transportation, according to our assumptions of duration and temperature. The other two scenarios did not significantly affect risk. The choice of dose‐response parameters was not critical for evaluation of control measures. 相似文献
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Koichi Hasegawa 《International Journal of Japanese Sociology》1995,4(1):21-36
Abstract In contrast with skepticism in most western advanced countries, recent east Asian countries share pro-nuclear energy policy. Using my scheme of “the enlarged political process model” and qualitative data from my case studies in Japan and the United States, this paper analyzes the main characteristics of the nuclear energy issues and citizens' movements in both countries. Four historical stages of anti-nuclear energy movement in Japan are analyzed focusing on main actors, issues, value orientation and mode of action. The socio-political reasons for the failure in gaining more wide-spread political influence in the last three stages are examined. In the US, a more decentralized and relatively open system pushed movements toward an instrumental and policy-oriented posture. Especially in California in recent years, in collaboration with state regulatory agencies and electrical utilities. environmental groups were the major influence on changes in the management of utilities for the post nuclear era, by stressing energy efficiency and exploring renewable energy resources. 相似文献