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21.
We argue that responsible conduct research (RCR) instruction should be extended beyond students and trainees funded by the National Institutes of Health (NIH) or National Science Foundation (NSF) to include all students, trainees, faculty, and research staff involved in research. Extending the scope of RCR instruction can help institutions develop and maintain an environment that promotes ethical research conduct. Universities and scientific organizations have objected to expanding the scope of RCR instruction on the grounds that it would be a major undertaking that would require the expenditure of additional institutional resources. We argue, however, that expanding the scope of RCR instruction can be done efficiently without placing undue burdens on institutions.  相似文献   
22.
Considerable progress has been made in applying Markov chain Monte Carlo (MCMC) methods to the analysis of epidemic data. However, this likelihood based method can be inefficient due to the limited data available concerning an epidemic outbreak. This paper considers an alternative approach to studying epidemic data using Approximate Bayesian Computation (ABC) methodology. ABC is a simulation-based technique for obtaining an approximate sample from the posterior distribution of the parameters of the model and in an epidemic context is very easy to implement. A new approach to ABC is introduced which generates a set of values from the (approximate) posterior distribution of the parameters during each simulation rather than a single value. This is based upon coupling simulations with different sets of parameters and we call the resulting algorithm coupled ABC. The new methodology is used to analyse final size data for epidemics amongst communities partitioned into households. It is shown that for the epidemic data sets coupled ABC is more efficient than ABC and MCMC-ABC.  相似文献   
23.
Abstract

Distance is an integral dimension of migration; yet, in recent years, ignored in migration research except as a control variable. This study examines distance of 1975–80 interstate migration and several explanations for the relations between distance and characteristic of migrants and locations. While earlier research provides only a few findings to replicate, the literature is replete with suggestions concerning the relation between distance and both areal and individual characteristics. These include that distance represents transportation costs, psychic costs — e.g., separation from family and friends and cultural dissimilarity of areas — intervening opportunities and competing migrants, geographic scope of labor market and diminishing information about opportunities.

Observations are individual records from the 1980 one-in-ten-thousand PUMS files. The sample is restricted to nonblack, noninstitutionalized head of households, age 25 to 64 in 1980. Respondents must be civilians and residing in the contiguous 48 states in both 1975 and 1980. Individual characteristics include distance of migration, sex, age, marital status, nativity, education, personal income, occupation, employment status and student status. Most location characteristics are from County Statistics File 2. These characteristics include average wage, per capita income, unemployment, average number of days per year below freezing and variables on local government taxes, educational expenditures, health expenditure and welfare expenditures. Additionally, we use proportion of the population born in state of origin residing at destination as a measure of information flow between origin and destination. We correct for sample selection bias in restricting the study to migrants.

We find outmigration is shaped by characteristics of individuals; however, distance of migration is shaped by characteristics at locations. Findings lend support to an interpretation of distance reflecting psychic costs and information and are consistent with a cost/benefit view of factors contributing to distance of migration.  相似文献   
24.
By the mid-nineteenth century, the north east of England was home to the fourth largest Irish settlement in England. The 1851 census makes it possible to identify key features of this post-famine community and provides a basis for the exploration of non-quantitative sources. The Gateshead Irish community was the third largest in the north east, behind Newcastle and Sunderland. The census data can establish such key features as the spatial distribution of the Gateshead Irish, their occupational profile, age distribution, household size, marital status and the extent of intermarriage between the Irish and the host community. It will be shown that the concept of the ghetto does not apply to the Irish; that they were overwhelmingly employed in unskilled work; that they were, in general, older than the host community; and that there were a significant number of cases of intermarriage between the Irish and English.  相似文献   
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26.
Although a number of studies have uncovered evidence of age differences in religious involvement across the life course, there has been a lack of long-term longitudinal data to test the extent to which these differences are due to changes within individuals over time. This study tracks trajectories of change in religious service attendance using data collected longitudinally over the course of up to 34 years, between 1971 and 2005, and in ages ranging from 15 to 102. Piecewise growth curve modeling was used to examine changes in the patterns of age-related change in three distinct developmental periods: the transition from adolescence to young adulthood, middle adulthood, and older adulthood. Attendance showed an average pattern of quadratic decline in adolescence, stability in middle adulthood, and a quadratic pattern of more rapid increase followed by decrease over the course of older adulthood. These results suggest that developmental factors play a role in changing patterns of religious participation across the adult life course, and may account for some of the apparent differences between age groups.  相似文献   
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28.
Although recent studies examine overall fertility trends in West Africa, few using advanced demographic techniques focus on adolescents. This study explores long‐term patterns of adolescent childbearing in 12 West African countries using 51 Demographic and Health Surveys covering birth cohorts that span 54 years (1940–1994). We employ classic demographic measures as well as disaggregation by early‐ (10–14 years old), middle‐ (15–17), and late adolescence (18–19). Cohort‐based estimates of total adolescent births, parity progression ratios, and rapid repeat birth probabilities reveal little change over time. Most women begin childbearing in adolescence, the progression to additional adolescent births remains common, and the incidence of rapid repeat births is high. In recent cohorts, women exit adolescence with an average of between 0.4 (Ghana) to 1.3 (Niger) births. Contrary to common assumptions, it is women commencing motherhood in early‐ and middle‐, not later adolescence, who account for most West African adolescent fertility.  相似文献   
29.
Janssen and Daniel analyzed the choice between a one- or a two-point conversion for a particular game situation in college football. Their decision criteria was maximum expected utility based on a von Neumann-Morgenstern utility function defined over the games outcomes. An alternative approach based on a stochastic dominance criterion is presented that does not rely on knowledge of the relative importance of tying vs. winning; rather, it relies on a notion of consistency in the sequential problem.  相似文献   
30.
The historical core of the independent sector is comprised of churches, charitable organisations and higher education. What distinguishes these and other independent sector organisations from the governmental and commercial sectors is the fact that participation in the independent sector is free from state compulsion and not for the purpose of monetary gain. The independent sector is a modern development which could not have occurred without the disestablishment of religion. Disestablished churches have given rise to secular charities, higher education and other independent sector organisations in the United States. The independent sector is the arena in which cultural production and altruistic activities with a distinctive moral quality take place. Participation in the independent sector is the only mechanism for status legitimation in a democractic society with no compulsory state religion or traditional forms of authority.  相似文献   
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