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41.

The feeder assignment and assembly sequence problem in printed circuit board (PCB) assembly with the twin objectives of minimizing magazine travel time and minimizing board travel time is presented in this study. The problem uses Dynamic Pick-and-Place (DPP) model where robot arm, board and magazine move together with different speeds based on relative coordinates between consecutive assembled points. The difficulty of the problem is that the feeder assignment depends on assembly sequence and vice versa. A new approach is proposed to improve the existing approaches. The trade-off between two strategies, assembly by area and assembly by component types, can give better results. The numerical experiments proved the efficiency of the new algorithm.  相似文献   
42.
We present a primal-dual ?log(n)?-approximation algorithm for the version of the asymmetric prize collecting traveling salesman problem, where the objective is to find a directed tour that visits a subset of vertices such that the length of the tour plus the sum of penalties associated with vertices not in the tour is as small as possible. The previous algorithm for the problem (V.H. Nguyen and T.T Nguyen in Int. J. Math. Oper. Res. 4(3):294–301, 2012) which is not combinatorial, is based on the Held-Karp relaxation and heuristic methods such as the Frieze et al.’s heuristic (Frieze et al. in Networks 12:23–39, 1982) or the recent Asadpour et al.’s heuristic for the ATSP (Asadpour et al. in 21st ACM-SIAM symposium on discrete algorithms, 2010). Depending on which of the two heuristics is used, it gives respectively 1+?log(n)? and $3+ 8\frac{\log(n)}{\log(\log(n))}$ as an approximation ratio. Our algorithm achieves an approximation ratio of ?log(n)? which is weaker than $3+ 8\frac{\log(n)}{\log(\log(n))}$ but represents the first combinatorial approximation algorithm for the Asymmetric Prize-Collecting TSP.  相似文献   
43.
One of the challenges in the design of confirmatory trials is to deal with uncertainties regarding the optimal target population for a novel drug. Adaptive enrichment designs (AED) which allow for a data-driven selection of one or more prespecified biomarker subpopulations at an interim analysis have been proposed in this setting but practical case studies of AEDs are still relatively rare. We present the design of an AED with a binary endpoint in the highly dynamic setting of cancer immunotherapy. The trial was initiated as a conventional trial in early triple-negative breast cancer but amended to an AED based on emerging data external to the trial suggesting that PD-L1 status could be a predictive biomarker. Operating characteristics are discussed including the concept of a minimal detectable difference, that is, the smallest observed treatment effect that would lead to a statistically significant result in at least one of the target populations at the interim or the final analysis, respectively, in the setting of AED.  相似文献   
44.
Increasing participation in family decision making is an integral part of adolescent development. This paper uses longitudinal data from four low and middle income countries—Ethiopia, India, Peru and Vietnam—to assess the relationship between young people's involvement in schooling decision making and schooling outcomes. In the pooled sample, compared to young adults who indicate to have no say in educational choices at age 19, adolescents who make these decisions unilaterally or jointly with parents are on average 17%–23% more likely to drop out by age 22. The effects are, however, heterogenous across countries.  相似文献   
45.
Social Indicators Research - Credit is commonly considered an important instrument to relieve financial capital constraints of poor households and subsequently to improve their welfare. However,...  相似文献   
46.
A new exchange algorithm for the construction of (M, S)-optimal incomplete block designs (IBDS) is developed. This exchange algorithm is used to construct 973 (M, S)-optimal IBDs (v, k, b) for v= 4,…,12 (varieties) with arbitrary v, k (block size) and b (number of blocks). The efficiencies of the “best” (M, S)-optimal IBDs constructed by this algorithm are compared with the efficiencies of the corresponding nearly balanced incomplete block designs (NBIBDs) of Cheng(1979), Cheng & Wu (1981) and Mitchell & John(1976).  相似文献   
47.
A new diagnostic method for VARMA(p,q) time series models is introduced. The procedure is based on a statistic that generalizes to a multivariate setting the properties of the usual univariate ARMA(p,q) residual correlations. A multiple version of the cumulative periodogram statistic is also suggested. Simulation studies and one real data application are presented.  相似文献   
48.
Today??s working adults often display different leadership orientations, as well as moderate to severe levels of stress depending on the situation and various demographic traits. In order to explore the stress, task orientation and relationship orientation variables of German people, this study examined the differences of 232 respondents in Germany based on their gender, age, and public sector work experience. The results showed that respondents had dissimilar scores on their leadership orientations. Younger respondents had significantly lower task and relationship orientation scores. Furthermore, females reported having a significantly higher level of stress perception. These findings are useful for expatriate managers and professionals who work with German-born workers. Besides, relevant literature on the German culture, suggestions and implications for future studies are presented.  相似文献   
49.
To determine whether depressive symptoms are elevated within months of adoption, we compared women who had recently adopted a toddler from an overseas orphanage to women with children of the same age who adopted more than a year before or were raising a child they birthed. The groups did not differ significantly in means or in percentage with elevated symptoms (Session 1, χ2(2) = 2.5, ns; Session 2, χ2(2) = 1.38, ns). The results provided no evidence of elevated symptoms in the first months following adoption for women who adopted internationally relative to other women with toddler-aged children.  相似文献   
50.
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