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51.
In this article, a classification model based on the majority rule sorting (MR‐Sort) method is employed to evaluate the vulnerability of safety‐critical systems with respect to malevolent intentional acts. The model is built on the basis of a (limited‐size) set of data representing (a priori known) vulnerability classification examples. The empirical construction of the classification model introduces a source of uncertainty into the vulnerability analysis process: a quantitative assessment of the performance of the classification model (in terms of accuracy and confidence in the assignments) is thus in order. Three different app oaches are here considered to this aim: (i) a model–retrieval‐based approach, (ii) the bootstrap method, and (iii) the leave‐one‐out cross‐validation technique. The analyses are presented with reference to an exemplificative case study involving the vulnerability assessment of nuclear power plants.  相似文献   
52.
This article discusses the unequal impact of Covid-19 on the lives of the children of survivors of modern slavery, child victims of exploitation and children at risk of exploitation in the UK. It draws on research that has analysed the risks and impacts of Covid-19 on victims and survivors of modern slavery. It explores how pandemic responses may have hindered these children's rights to education, food, safety, development and participation and representation in legal processes. It suggests that the pandemic should be used as an impetus to address inequalities that existed pre-Covid-19 and those that have been exacerbated by it.  相似文献   
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In recent years, there has been a great deal of literature published concerning the identification of predictive biomarkers and indeed, an increasing number of therapies have been licenced on this basis. However, this progress has been made almost exclusively on the basis of biomarkers measured prior to exposure to treatment. There are quite different challenges when the responding population can only be identified on the basis of outcomes observed following exposure to treatment, especially if it represents only a small proportion of patients. The purpose of this paper is to explore whether or when a treatment could be licenced on the basis of post‐treatment predictive biomarkers (PTPB), the focus is on oncology but the concepts should apply to all therapeutic areas. We review the potential pitfalls in hypothesising the presence of a PTPB. We also present challenges in trial design required to confirm and licence on the basis of a PTPB: what's the control population?, could there be a detriment to non‐responders by exposure to the new treatment?, can responders be identified rapidly?, could prior exposure to the new treatment adversely affect performance of the control in responders? Nevertheless, if the patients to be treated could be rapidly identified after prior exposure to treatment, and without harm to non‐responders, in appropriately designed and analysed trials, may be more targeted therapies could be made available to patients. Copyright © 2014 John Wiley & Sons, Ltd.  相似文献   
55.
Daly T, Szebehely M. Unheard voices, unmapped terrain: care work in long‐term residential care for older people in Canada and Sweden This article aims to contribute to comparative welfare state research by analysing the everyday work life of long‐term care facility workers in Canada and Sweden. The study's empirical base was a survey of fixed and open‐ended questions. The article presents results from a subset of respondents (care aides and assistant nurses) working in facilities in three Canadian provinces (n= 557) and across Sweden (n= 292). The workers' experiences were linked to the broader economic and organisational contexts of residential care in the two jurisdictions. We found a high degree of country‐specific differentiation of work organisation: Canada follows a model of highly differentiated task‐oriented work, whereas Sweden represents an integrated relational care work model. Reflecting differences in the vertical division of labour, the Canadian care aides had more demanding working conditions than their Swedish colleagues. The consequences of these models for care workers, for older people and for their families are discussed.  相似文献   
56.
Most states' adult or elder protective services and aging agency personnel prepare annual reports about their protective services. These reports vary by state and have different terms for the reporter of abuse. Reviewing annual reports from 46 states and the District of Columbia, 248 different terms were used for the reporter of abuse. To develop essential data elements for reporters of abuse, a literature search, a compilation of state elder abuse annual report list of abuse reporters, and a sorting exercise were conducted. Eleven terms were recommended for the different reporters of abuse, encouraging all state administrators and caseworkers to reach consensus to standardize the language.  相似文献   
57.
This article presents the new method of self-interviewing as an empirical tool specifically for use in memory studies research. The article traces some of the empirical limitations specific to the field of memory studies and reviews the existing tools used in this area. It particularly focuses on some of the limitations of qualitative interviewing, the memory work method and diary methods in generating data on the processes of vernacular remembering at the same time as making visible the meaning that remembering has for participants in their everyday lives. We propose the self-interview as a method which addresses some of these limitations. In elaborating the value of the self-interview, we draw extensively on fieldwork that we have conducted using this method. Although the self-interview does not divest memory studies of the need for a range of other methods, the self-interview is an important addition to its currently rather sparse methodological tool kit.  相似文献   
58.
The use of trauma-informed practices in the child welfare system is critically important to prevent system-induced trauma and encourage timely assessment, triage and referral for care when indicated. Ultimately, such measures have the potential over time to decrease the risk for mental health problems in children exposed to a trauma. This study evaluates an initiative in Arkansas to train child welfare front-line staff members in trauma-informed care practices. We evaluated the impact of the training on knowledge and use of trauma-informed care practices among three types of child welfare staff (Caseworkers, Program Assistants and Other front-line staff). Results suggest that this training process was highly successful in improving knowledge of trauma-informed care practices, especially among staff with the least formal education and training. We also found a significant increase in staff use of trauma-informed care practices at the three-month follow-up with little difference observed across staff groups. Barriers that may prevent staff from full implementation of training concepts are described and strategies to address barriers are proposed.  相似文献   
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Drawing on attachment theory, the author explores the particular physical presence of the body as a significant aspect of the attachment relationship between two people, most notably between two females (the mother and the daughter). Recognizing the nature of one’s body attachment as a protective and a risk factor provides a greater understanding of the potential for resilience, as well as the presence of vulnerability in relationship to one’s body. Through a case application, the author argues that without a model of secure attachment to the body, a female is more likely to develop an attachment to cultural ideals as an extension of primary relationships and at the expense of her own body, moving her from exposure to action in the form of an eating disorder.  相似文献   
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