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231.
The varied maladaptive behavioral, social, medical, and psychiatric outcomes associated with maltreatment in childhood have been extensively documented in the extant empirical literature. In this review, we examine the adverse impact of the stress associated with child maltreatment on the regulation of the neurobiological stress systems, alterations in brain maturation, and neuropsychological outcomes in the developing child. Further, we provide a detailed discussion of the pathway between the psychobiological consequences of trauma and subsequent cognitive, language, and academic deficits that often have a deleterious impact on global functioning. We review neuroimaging techniques and the empirical results of studies utilizing such techniques to examine brain maturation in maltreated children and individuals with posttraumatic stress disorder. We address the practice, research, and policy implications of the psychobiological sequelae of child maltreatment and offer future directions for research.  相似文献   
232.
Our first goal was to examine the relations among observational, physiological, and self‐report measures of children's anger. Our second goal was to investigate whether these relations varied by reactive or proactive aggression. Children (272 second‐grade boys and girls) participated in a procedure in which they lost a game and prize to a confederate who cheated. Skin conductance reactivity, heart rate reactivity, self‐reports of anger, angry facial expressions, and angry nonverbal behaviors were measured for each turn of the game. We used multi‐level regressions to calculate the relations among the 10 pairs of the five anger variables over the course of the game. Six of the 10 pairs of anger variables were positively related. These findings suggest that measuring children's anger using any one approach may not capture the full complexity of children's overall experience and expression of anger. Furthermore, three of the 10 relations were stronger at higher levels of reactive aggression, although none varied by proactive aggression. These findings suggest that reactive aggression is related to greater cohesiveness in the experience and expression of anger than is proactive aggression.  相似文献   
233.
The AIDS epidemic in sub‐Saharan Africa is fertile ground for examining how moral evaluations evolve over time and across different settings. We compare the discourse on AIDS in Malawi as presented in the media with that of everyday conversations. Drawing on two sets of texts, newspaper articles and conversational journals, produced over a ten‐year period from 1999 through 2008, we analyze their moral injunctions, or what individuals should or should not do in response to the AIDS epidemic. The predominant injunctions in the early years in both sources were premarital abstinence and marital fidelity. Following the introduction of HIV testing and treatment, however, the discourses diverged. Discourse in the media turned toward moral injunctions requiring individuals to interact with authoritative institutions; thus the conceptual center of gravity of the struggle against AIDS in the media shifted from collectivities of individuals to collectivities of institutions. Rural Malawians, however, received these moral injunctions with great skepticism and continued to advise each other to prevent death by controlling one's sexual appetites.  相似文献   
234.
This paper considers the object of the syringe-in-use for IV drug users. Via an engagement with performative stories of the “rush” I suggest this object experience concerns not a conditioned effect but the materiality of the syringe itself. I also suggest that an analysis of the rush as a technical materialization challenges existing interpretations of heroin use. In particular, it challenges understandings of the syringe as an object that threatens a coherent body image, gender identity, and sexed differences.  相似文献   
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The application of quantitative microbial risk assessments (QMRAs) to understand and mitigate risks associated with norovirus is increasingly common as there is a high frequency of outbreaks worldwide. A key component of QMRA is the dose–response analysis, which is the mathematical characterization of the association between dose and outcome. For Norovirus, multiple dose–response models are available that assume either a disaggregated or an aggregated intake dose. This work reviewed the dose–response models currently used in QMRA, and compared predicted risks from waterborne exposures (recreational and drinking) using all available dose–response models. The results found that the majority of published QMRAs of norovirus use the 1F1 hypergeometric dose–response model with α = 0.04, β = 0.055. This dose–response model predicted relatively high risk estimates compared to other dose–response models for doses in the range of 1–1,000 genomic equivalent copies. The difference in predicted risk among dose–response models was largest for small doses, which has implications for drinking water QMRAs where the concentration of norovirus is low. Based on the review, a set of best practices was proposed to encourage the careful consideration and reporting of important assumptions in the selection and use of dose–response models in QMRA of norovirus. Finally, in the absence of one best norovirus dose–response model, multiple models should be used to provide a range of predicted outcomes for probability of infection.  相似文献   
239.
In this article I consider the impact of social epistemologies for understanding the object of the syringe. My aim is to examine the process through which the syringe transforms from an injecting device to a tool of social and political inquiry. Paying particular attention to the uses of Foucault, Becker, Bourdieu, Freud and Latour in empirical studies of injecting heroin use, I examine the sociology of the syringe through the lens of habit and habitus, discourse and deviance, mourning and melancholia, attachment and agencement. In pursuing the theory behind the object my goal is to address a sociological object in the making. In so doing I show how the syringe has been significant for social research, social theory, and sociology. It is the difference the object makes that this article seeks to describe. In tracing the epistemology of the syringe I show how the object is important not just for knowledge of addiction but sociology itself.  相似文献   
240.
Population Research and Policy Review - In recent years, a historically unprecedented number of Mexican migrants to the U.S. returned to Mexico. Compared to previous cohorts, recent return migrants...  相似文献   
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