The generalized log-gamma mixture model with covariates: local influence and residual analysis

In a sample of censored survival times, the presence of an immune proportion of individuals who are not subject to death, failure or relapse, may be indicated by a relatively high number of individuals with large censored survival times. In this paper the generalized log-gamma model is modified for the possibility that long-term survivors may be present in the data. The model attempts to separately estimate the effects of covariates on the surviving fraction, that is, the proportion of the population for which the event never occurs. The logistic function is used for the regression model of the surviving fraction. Inference for the model parameters is considered via maximum likelihood. Some influence methods, such as the local influence and total local influence of an individual are derived, analyzed and discussed. Finally, a data set from the medical area is analyzed under the log-gamma generalized mixture model. A residual analysis is performed in order to select an appropriate model. The authors would like to thank the editor and referees for their helpful comments. This work was supported by CNPq, Brazil.     

Multivariate Kendall's tau for change‐point detection in copulas

Statistical procedures for the detection of a change in the dependence structure of a series of multivariate observations are studied in this work. The test statistics that are proposed are $L_1$ , $L_2$ , and $L_{\infty }$ distances computed from vectors of differences of Kendall's tau; two multivariate extensions of Kendall's measure of association are used. Since the distributions of these statistics under the null hypothesis of no change depend on the unknown underlying copula of the vectors, a procedure based on the multiplier central limit theorem is used for the computation of p‐values; the method is shown to be valid both asymptotically and for moderate sample sizes. Alternative versions of the tests that take into account possible breakpoints in the marginal distributions are also investigated. Monte Carlo simulations show that the tests are powerful under many scenarios of change‐point. In addition, two estimators of the time of change are proposed and their efficiency is carefully studied. The methodologies are illustrated on simulated series from the Canadian Regional Climate Model. The Canadian Journal of Statistics 41: 65–82; 2013 © 2012 Statistical Society of Canada     

On the recoding of continuous and bounded indexes to a binomial form: an application to quality-of-life scores

The statistical analysis of patient-reported outcomes (PROs) as endpoints has shown to be of great practical relevance. The resulting scores or indexes from the questionnaires used to measure PROs could be treated as continuous or ordinal. The goal of this study is to propose and evaluate a recoding process of the scores, so that they can be treated as binomial outcomes and, therefore, analyzed using logistic regression with random effects. The general methodology of recoding is based on the observable values of the scores. In order to obtain an optimal recoding, the evaluation of the recoding method is tested for different values of the parameters of the binomial distribution and different probability distributions of the random effects. We illustrate, evaluate and validate the proposed method of recoding with the Short Form-36 (SF-36) Survey and real data. The optimal recoding approach is very useful and flexible. Moreover, it has a natural interpretation, not only for ordinal scores, but also for questionnaires with many dimensions and different profiles, where a common method of analysis is desired, such as the SF-36.     

Distance-based approach in univariate longitudinal data analysis

In this paper, we propose a methodology to analyze longitudinal data through distances between pairs of observations (or individuals) with regard to the explanatory variables used to fit continuous response variables. Restricted maximum-likelihood and generalized least squares are used to estimate the parameters in the model. We applied this new approach to study the effect of gender and exposure on the deviant behavior variable with respect to tolerance for a group of youths studied over a period of 5 years. Were performed simulations where we compared our distance-based method with classic longitudinal analysis with both AR(1) and compound symmetry correlation structures. We compared them under Akaike and Bayesian information criterions, and the relative efficiency of the generalized variance of the errors of each model. We found small gains in the proposed model fit with regard to the classical methodology, particularly in small samples, regardless of variance, correlation, autocorrelation structure and number of time measurements.     

On the existence of a normal approximation to the distribution of the ratio of two independent normal random variables

The distribution of the ratio of two independent normal random variables X and Y is heavy tailed and has no moments. The shape of its density can be unimodal, bimodal, symmetric, asymmetric, and/or even similar to a normal distribution close to its mode. To our knowledge, conditions for a reasonable normal approximation to the distribution of Z = X/Y have been presented in scientific literature only through simulations and empirical results. A proof of the existence of a proposed normal approximation to the distribution of Z, in an interval I centered at β = E(X) /E(Y), is given here for the case where both X and Y are independent, have positive means, and their coefficients of variation fulfill some conditions. In addition, a graphical informative way of assessing the closeness of the distribution of a particular ratio X/Y to the proposed normal approximation is suggested by means of a receiver operating characteristic (ROC) curve.     

Functional sliced inverse regression analysis

Most of the usual multivariate methods have been extended to the context of functional data analysis. Our contribution concerns the study of sliced inverse regression (SIR) when the response variable is real but the regressor is a function. In the first part, we show how the relevant properties of SIR remain essentially the same in the functional context under suitable conditions. Unfortunately, the estimation procedure used in the multivariate case cannot be directly transposed to the functional one. Then, we propose a solution that overcomes this difficulty and we show the consistency of the estimates of the parameters of the model.     

Parameter selection in modified histogram estimates

A multivariate modified histogram density estimate depending on a reference density g and a partition P has been proved to have good consistency properties according to several information theoretic criteria. Given an i.i.d. sample, we show how to select automatically both g and P so that the expected L ₁ error of the corresponding selected estimate is within a given constant multiple of the best possible error plus an additive term which tends to zero under mild assumptions. Our method is inspired by the combinatorial tools developed by Devroye and Lugosi [Devroye, L. and Lugosi, G., 2001, Combinatorial Methods in Density Estimation (New York, NY: Springer–Verlag)] and it includes a wide range of reference density and partition models. Results of simulations are also presented.     

Kernel density estimation for heavy-tailed distributions using the champernowne transformation

When estimating loss distributions in insurance, large and small losses are usually split because it is difficult to find a simple parametric model that fits all claim sizes. This approach involves determining the threshold level between large and small losses. In this article, a unified approach to the estimation of loss distributions is presented. We propose an estimator obtained by transforming the data set with a modification of the Champernowne cdf and then estimating the density of the transformed data by use of the classical kernel density estimator. We investigate the asymptotic bias and variance of the proposed estimator. In a simulation study, the proposed method shows a good performance. We also present two applications dealing with claims costs in insurance.     

Mean estimation with data missing at random for functional covariables

In a missing-data setting, we want to estimate the mean of a scalar outcome, based on a sample in which an explanatory variable is observed for every subject while responses are missing by happenstance for some of them. We consider two kinds of estimates of the mean response when the explanatory variable is functional. One is based on the average of the predicted values and the second one is a functional adaptation of the Horvitz–Thompson estimator. We show that the infinite dimensionality of the problem does not affect the rates of convergence by stating that the estimates are root-n consistent, under missing at random (MAR) assumption. These asymptotic features are completed by simulated experiments illustrating the easiness of implementation and the good behaviour on finite sample sizes of the method. This is the first paper emphasizing that the insensitiveness of averaged estimates, well known in multivariate non-parametric statistics, remains true for an infinite-dimensional covariable. In this sense, this work opens the way for various other results of this kind in functional data analysis.     

Importance of the prior mass for agreement between frequentist and Bayesian approaches in the two-sided test

We study distributional properties of generalized order statistics (gos) related by a random shift or scaling scheme in the continuous and discrete case, respectively. In the continuous case, we obtain new characterizations of distributions relating non-neighbouring gos extending some results given in the literature for the neighbouring cases. On the other hand, in the discrete case, we investigate the existence and uniqueness of a discrete parent distribution supported on the integers whose gos are related by a random translation.