The Temporal Structure of Scientific Consensus Formation

This article engages with problems that are usually opaque: What trajectories do scientific debates assume, when does a scientific community consider a proposition to be a fact, and how can we know that? We develop a strategy for evaluating the state of scientific contestation on issues. The analysis builds from Latour's black box imagery, which we observe in scientific citation networks. We show that as consensus forms, the importance of internal divisions to the overall network structure declines. We consider substantive cases that are now considered facts, such as the carcinogenicity of smoking and the non-carcinogenicity of coffee. We then employ the same analysis to currently contested cases: the suspected carcinogenicity of cellular phones, and the relationship between vaccines and autism. Extracting meaning from the internal structure of scientific knowledge carves a niche for renewed sociological commentary on science, revealing a typology of trajectories that scientific propositions may experience en route to consensus.     

An extension of bayesian measure of information to regression

This paper extends Lindley's measure of average information to the linear model, E(Y∣ß) = Xß. An expression which quantifies the average amount of information provided by the nxl vector of observations Y about the pxl vector of coefficient parameters ß will be derived. The effect of the structure of the regressor matrix, X, on the information measure is discussed. An information theoretic optimal design is characterized. Some applications are suggested.     

Inference on effect size indices from several two-armed experiments

The statistical inference problem on effect size indices is addressed using a series of independent two-armed experiments from k arbitrary populations. The effect size parameter simply quantifies the difference between two groups. It is a meaningful index to be used when data are measured on different scales. In the context of bivariate statistical models, we define estimators of the effect size indices and propose large sample testing procedures to test the homogeneity of these indices. The null and non-null distributions of the proposed testing procedures are derived and their performance is evaluated via Monte Carlo simulation. Further, three types of interval estimation of the proposed indices are considered for both combined and uncombined data. Lower and upper confidence limits for the actual effect size indices are obtained and compared via bootstrapping. It is found that the length of the intervals based on the combined effect size estimator are almost half the length of the intervals based on the uncombined effect size estimators. Finally, we illustrate the proposed procedures for hypothesis testing and interval estimation using a real data set.     

Estimation of a discriminant function from a mixture of two inverse Weibull distributions

The classification of a random variable based on a mixture can be meaningfully discussed only if the class of all finite mixtures is identifiable. In this paper, we find the maximum-likelihood estimates of the parameters of the mixture of two inverse Weibull distributions by using classified and unclassified observations. Next, we estimate the nonlinear discriminant function of the underlying model. Also, we calculate the total probabilities of misclassification as well as the percentage bias. In addition, we investigate the performance of all results through a series of simulation experiments by means of relative efficiencies. Finally, we analyse some simulated and real data sets through the findings of the paper.     

A simple approximation for the doubly noncentral t-distribution

A simple approximation for the doubly noncentral t-distribution, based upon the Fieller-Geary Theorem (1930) and approximate normality of the square root of the noncentral chi-square variable observed by Patnaik (1949), is developed, This approximation and an Edgeworth series expansion associated with it are evaluated. The simple approximation is seen to be reasonably accurate for most practical purposes.     

Alternative Methods for Computing the Sensitivity of Complex Surveillance Systems

Stochastic scenario trees are a new and popular method by which surveillance systems can be analyzed to demonstrate freedom from pests and disease. For multiple component systems—such as a combination of a serological survey and systematically collected observations—it can be difficult to represent the complete system in a tree because many branches are required to represent complex conditional relationships. Here we show that many of the branches of some scenario trees have identical outcomes and are therefore redundant. We demonstrate how to prune branches and derive compact representations of scenario trees using matrix algebra and Bayesian belief networks. The Bayesian network representation is particularly useful for calculation and exposition. It therefore provides a firm basis for arguing disease freedom in international forums.     

Maximum likelihood estimation of the bimodal failure rate for censored and tied observations

DIMITROV, RACHEV and YAKOVLEV ( 1985 ) have obtained the isotonic maximum likelihood estimator for the bimodal failure rate function. The authors considered only the complete failure time data. The generalization of this estimator for the case of censored and tied observations is now proposed.