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In many experiments where data have been collected at two points in time (pre-treatment and post-treatment), investigators wish to determine if there is a difference between two treatment groups. In recent years it has been proposed that an appropriate statistical analysis to determine if treatment differences exist is to use the post-treatment values as the primary comparison variables and the pre-treatment values as covariates. When there are several outcome variables, we propose new tests based on residuals as alternatives to existing methods and investigate how the powers of the new and existing tests are affected by various choices of covariates. The limiting distribution of the test statistic of the new test based on residuals is given. Monte Carlo simulations are employed in the power comparisons.  相似文献   
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The authors develop consistent nonparametric estimation techniques for the directional mixing density. Classical spherical harmonics are used to adapt Euclidean techniques to this directional environment. Minimax rates of convergence are obtained for rotation ally invariant densities verifying various smoothness conditions. It is found that the differences in smoothness between the Laplace, the Gaussian and the von Mises‐Fisher distributions lead to contrasting inferential conclusions.  相似文献   
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This paper provides insights into the dynamics of attention to TV commercials via an analysis of the length of time that commercials are viewed before being 'zapped'. The model, which incorporates a flexible baseline hazard rate and captures unobserved heterogeneity across both consumers and commercials using a hierarchical Bayes approach, is estimated on two datasets in which commercial viewing is captured by a passive online device that continually monitors a household's TV viewing. Consistent with previous findings in psychology about the nature of attentional engagement in TV viewing, baseline hazard rates are found to be non-monotonic. In addition, the data show considerable ad-to-ad and household-to-household heterogeneity in zapping behavior. While one of the datasets contains some information on characteristics of the ads, these data do not reveal any firm links between the ad heterogeneity and the ad characteristics. A number of methodological and computational issues arise in the hierarchical Bayes analysis.  相似文献   
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Based on sero-prevalence data of rubella, mumps in the UK and varicella in Belgium, we show how the force of infection, the age-specific rate at which susceptible individuals contract infection, can be estimated using generalized linear mixed models (McCulloch & Searle, 2001). Modelling the dependency of the force of infection on age by penalized splines, which involve fixed and random effects, allows us to use generalized linear mixed models techniques to estimate both the cumulative probability of being infected before a given age and the force of infection. Moreover, these models permit an automatic selection of the smoothing parameter. The smoothness of the estimated force of infection can be influenced by the number of knots and the degree of the penalized spline used. To determine these, a different number of knots and different degrees are used and the results are compared to establish this sensitivity. Simulations with a different number of knots and polynomial spline bases of different degrees suggest - for estimating the force of infection from serological data - the use of a quadratic penalized spline based on about 10 knots.  相似文献   
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This paper investigates the role that performance-based regulations can play in linking a firm's environmental, health, and safety concerns with their corporate strategy. The specific focus is on the performance standards required by the Clean Air Act Amendments (CAAA) which require firms that store or use certain chemicals to develop a Risk Management Plan (RMP) for reducing the likelihood and impact of accidents at their plants. Data from a series of case studies and interviews of executives in chemical firms reveal that proactive companies integrated many of the requirements of the CAAA into their management systems prior to the regulatory requirements. Most of these firms tend to be large ones. Small firms often lack the resources to implement these regulations and hence have tended to have a more difficult time with compliance.  相似文献   
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Risk,Media, and Stigma at Rocky Flats   总被引:1,自引:0,他引:1  
Flynn  James  Peters  Ellen  Mertz  C. K.  Slovic  Paul 《Risk analysis》1998,18(6):715-727
Public responses to nuclear technologies are often strongly negative. Events, such as accidents or evidence of unsafe conditions at nuclear facilities, receive extensive and dramatic coverage by the news media. These news stories affect public perceptions of nuclear risks and the geographic areas near nuclear facilities. One result of these perceptions, avoidance behavior, is a form of technological stigma that leads to losses in property values near nuclear facilities. The social amplification of risk is a conceptual framework that attempts to explain how stigma is created through media transmission of information about hazardous places and public perceptions and decisions. This paper examines stigma associated with the U.S. Department of Energy's Rocky Flats facility, a major production plant in the nation's nuclear weapons complex, located near Denver, Colorado. This study, based upon newspaper analyses and a survey of Denver area residents, finds that the social amplification theory provides a reasonable framework for understanding the events and public responses that took place in regard to Rocky Flats during a 6-year period, beginning with an FBI raid of the facility in 1989.  相似文献   
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