肥胖基因

肥胖症已经逐渐成为了一个严重的健康问题和社会问题 ,对肥胖症的研究已深入到分子水平。自肥胖基因被克隆以来 ,针对肥胖基因的结构、突变、表达及其产物的生物学作用已进行了大量的研究。本文就肥胖基因的发现和定位、结构和突变及其产物———瘦素的相关研究进行了综述 ,并指出了对肥胖基因进行深入研究的相关领域     

Acknowledgment of outside reviewers for 1994

Acknowledgment of outside reviewers for 1994     

In Whose Backyard?: Concern About Siting a Nuclear Waste Facility*

Proponents of hazardous and nuclear waste depositories label opponents to local siting of such facilities “NIMBYs” (Not In My Backyard). This study assesses the extent to which the NIMBY label and the strategies of industry proponents to reduce opposition function on a reasonable set of assumptions. Using survey data and multiple regression techniques, the levels of concern of residents living in the county selected as the site of a low level radioactive waste disposal facility (imminent threat condition) are compared with a statewide sample (hypothetical threat condition). Consistent with proponents' theoretical assumptions, the levels of concern are greater for respondents under conditions of imminent threat than of hypothetical threat. However, within the host county, levels of concern are lowest, albeit most polarized, in the community closest to the proposed site. A conflict theory approach enhances an understanding of these findings by suggesting that within the most proximate community levels of concern are lowest for citizens who stand to gain the most economic benefits from the facility but highest for those citizens who are least likely to derive tangible gains.     

Aid, Relief, and Containment: The First Asylum Country and Beyond

A fundamental problem that confronts the European Union today is how it can maintain its commitment to the institution of asylum while checking irregular migration and the abuse of its asylum system. In order to explore a response to this dilemma the paper addresses the following questions: what role can relief and aid policies play in influencing migration patterns? What should be the appropriate approach to the granting of relief and aid to developing countries of first asylum? Should it be viewed as a part of the larger problem of development or be treated as a distinct issue? What kind of a relief/aid model will help refugees return to post–conflict societies and stop the conflict from reproducing itself? The paper examines two different approaches to address these questions: the alliance–containment approach and the distributive–developmental approach. It also looks at some empirical evidence, which reveals that at present it is a conservative alliance–containment approach that informs EU relief and aid practices. This approach, however, does not help achieve the stated objective of checking abuse of asylum and migration procedures while sustaining a commitment to a liberal asylum regime. The paper goes on to identify the gaps in EU policy and the lessons that can be drawn. It concludes by looking at different policy alternatives and suggesting the adoption of a reformist distributive–developmental model. The implementation of this model holds out the hope of reverting to a more liberal asylum regime while controlling irregular migration and “bogus” asylum seekers, for the reformist distributive developmental model takes a more long–term view of migration trends and also seeks to address the growing North–South divide.     

Marital Conflict,Ineffective Parenting,and Children's and Adolescents' Maladjustment

Data from the 1988 National Survey on Families and Households were analyzed to examine the associations among marital conflict, ineffective parenting, and children's and adolescents' maladjustment. Parents' use of harsh discipline and low parental involvement helped explain the connection between marital conflict and children's maladjustment in children aged 2 through 11. Parent‐child conflict was measured only in families with a target teenager and also was a significant mediator. Although ineffective parenting explained part of the association between marital conflict and children's maladjustment, independent effects of marital conflict remained in families with target children aged 2 through 11 (but not for families with a teenager). With a few exceptions, this pattern of findings was consistent for mothers' and fathers' reports, for daughters and sons, for families with various ethnic backgrounds, and for families living in and out of poverty.     

Factors Associated with the Development of Nonmetropolitan Growth Nodes in Producer Services Industries, 1980–1990*

Abstract Over the 1980–1990 period, employment in producer services industries in the nonmetropolitan United States increased substantially. This growth resulted in the development of nonmetropolitan growth nodes in producer services industries. A growth node refers to a nonmetropolitan area that contains a greater than average concentration of employment in a particular industry sector relative to other nonmetropolitan areas. Moreover, this industry concentration not only increases over time, but also represents an important source of employment growth within the area. With nonmetropolitan counties as the spatial unit of analysis, 317 growth nodes in producer services industries are identified for the 1980–1990 period. Access to workers with clerical and administrative support skills, access to highly educated workers, higher earnings per employed worker, access to recreational amenities, and proximity to metropolitan areas were associated with the development of nonmetropolitan growth nodes in producer services industries during this period.     

On Masking and Revealing the Culture of the Cross-Culturalist

There is a gulf between the analytic and experiential aspects of cross-culturalists' functioning that is reflected in the split between explicit scientific rules for studying the culture of others, while following an informal oral tradition for considering our own cultural makeup. This article discusses both a possible strategy for correcting this situation and the barriers that are likely to prevent such a correction. Structured cultural self-study procedures are presented as a possible resource in the continuing development of graduate students and professionals, and these have already proven highly effective in teaching cross-cultural psychology to undergraduates. Fostering commitments to standardized self-study and to applications of experiential learning is currently not likely to flourish due to complex academic and epistemic traditions, discussed as six cultural self-masking factors. A specific self-study protocol is offered to provide a beginning point for generating improved reflexive methods and for individual trial use. Through disciplined reflexivity, benefits might emerge in the form of better bias control in research, enhanced external validity, and a new theory about the interplay of investigators' self-knowledge and the conduct of cross-cultural research.     

Hearts and Minds and Morality: Analyzing Moral Vocabularies in Qualitative Studies

A strategy of analyzing the moral vocabulary of a social movement or subculture is proposed by which ethnographies and other qualitative works may place the moral and ethical concepts used by respondents into a broader sociological context. Through examining the moral resources, the status hierarchy which the specific moral resources within a given moral vocabulary form, and the historical and cultural contexts within which these moral resources exist, it is argued that it becomes possible to analyze and anticipate the moral claims and form of discourse which will be produced by a specific movement and/or subculture. It is also argued that this method may be used to predict how the opposition to a movement and/or subculture is perceived through the formation of an antithetical moral vocabulary.