Workforce reentry for people with HIV/AIDS: intervention effects and predictors of success

Treatment that prolongs the lives of people with HIV/AIDS and improves their quality of life is relatively recent and little is known about factors that may predict their successful re-entry to the workforce. No data exist concerning the effectiveness of programs to assist people with HIV/AIDS in their efforts to return to work. We used logistic regression and Kaplan-Meier survival curves to predict return to work using data from 126 individuals who participated in an HIV/AIDS return to work program. Results from the 24 month follow-up revealed that program participation, general health, benefits status, and gender, predicted successful re-entry to the workforce. We discuss these findings in the context of the need for more explicitly-defined interventions, as well as the need for additional information on factors that may hinder or facilitate workforce re-entry among people with HIV/AIDS.     

A Gender-based Examination of Past-year Recreational Gamblers

Background Most adults gamble recreationally yet few studies have systematically investigated for gender-related differences in recreational gamblers.Methods Logistic regression analyses were performed on data from a nationally representative sample of respondents from the 1998 Gambling Impact and Behavior Study. Results Female gamblers versus non-gamblers were more likely to report use of alcohol and drugs. Male gamblers versus non-gamblers were more likely to report alcohol use and abuse/dependence, any substance abuse/dependence, and lifetime incarceration. An analysis of gambling by gender group interaction effects did not identify significant differences in health-related measures. Male as compared with female gamblers reported beginning gambling earlier, experiencing higher past-year maximal losses and wins, and finding favorite and engaging in different types of gambling.Conclusions Despite heavier gambling in male as compared with female recreational gamblers, similar mental health functioning was observed in female and male past-year recreational gamblers. Types of gambling problematic for men and women are reflected in the gambling preferences of recreational gamblers.     

A framework for providing telecommuting as a reasonable accommodation: some considerations on a comparative case study

Telecommuting, whether full time, part time, or over short periods when the need arises, can be an important accommodation for employees with disabilities. Indeed, telecommuting may be the only form of accommodation that offers employees whose disabilities fluctuate a means to stay consistently and gainfully employed. This article describes one employer's experience in considering a request for telecommuting as a reasonable accommodation for a particular employee. Drawing on real-life examples, both positive and negative, this article provides a win/win framework for decision-making that can help employers evaluate the use of telecommuting as a possible accommodation and facilitates open and ongoing communication between employer and employee.     

Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment

Membrane-bound endosomal vesicles play an integral role in multiple cellular events, including protein processing and turnover, and often critically regulate the cell-surface availability of receptors and other plasma membrane proteins in many different cell types. Neurons are no exception, being dependent on endosomal function for housekeeping and synaptic events. Growing evidence suggests a link between neuronal endosomal function and Alzheimer's disease (AD) pathophysiology. Endosomal abnormalities invariably occur within neurons in AD brains, and endocytic compartments are one likely site for the production of the pathogenic beta-amyloid peptide (Abeta), which accumulates within the brain during the disease and is generated by proteolytic processing of the amyloid precursor protein (APP). The enzymes and events involved in APP processing are appealing targets for therapeutic agents aimed at slowing or reversing the pathogenesis of AD. The neuronal endosome may well prove to be the intracellular site of action for inhibitors of beta-amyloidogenic APP processing. We present here the view that knowledge of the endosomal system in the disease can guide drug discovery of AD therapeutic agents.     

IT'S ALL ABOUT POWER:

What happens to rural communities in remote raw materials-rich regions when their definitions of the region's natural resources are confronted with competing and incompatible definitions presented and enforced by external actors? The social constructionist approach in environmental sociology provides an essential counterbalance to environmental determinism, but this article argues that in many contexts social construction is actually a process of the imposition of external actors' material interests over the objections of local groups. New historical materialism, via an interdisciplinary and multimethod research strategy, analyzes the changing definitions and uses of the Brazilian Amazon as a revelatory case study of the political economy and ecology of this process and its consequences for nature, rural communities, and indigenous peoples.     

A Longitudinal Analysis of Immigrant Occupational Mobility: A Test of the Immigrant Assimilation Hypothesis1

This article develops a model of the occupational mobility of immigrants and tests the hypotheses using data on males from the Longitudinal Survey of Immigrants to Australia, Panel I. The theoretical model generates hypotheses regarding a U‐shaped pattern of occupational mobility from the “last job” in the origin, to the “first job” in the destination, to subsequent jobs in the destination, and regarding the depth of the “U.” The survey includes data on pre‐immigration occupation, the “first” occupation in Australia (at six months) and the occupation after about three‐and‐a‐half years in Australia. The hypotheses are supported by the empirical analysis.     

The welfare economics of immigration control

This paper develops a Harris-Todaro (HT) type model of East-West migration in which labour market imperfections prevent market clearing in both blocs. The model encompasses two extremes of perfectly flexible wages with full employment on the one hand, and the HT scenario where the real wage in the host country is fixed, on the other. Welfare analysis compares the laissez-faire migration equilibrium based on explicit calculations of potential migrants without immigration controls in the West, with the socially optimal level of migration. The paper examines the issue of immigration control by developing a model of illegal immigration in which the incentives facing the potentially illegal immigrant are explicitly modelled. Received: 3 April 1997/Accepted 16 March 1998     

Exact short poisson confidence intervals

The authors propose a new method for constructing a confidence interval for the expectation θ of a Poisson random variable. The interval they obtain cannot be shortened without the infimum over θ of the coverage probability falling below 1 ‐ α. In addition, the endpoints of the interval are strictly increasing functions of the observed variable. An easy‐to‐program algorithm is provided for computing this interval.