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Longitudinal investigations play an increasingly prominent role in biomedical research. Much of the literature on specifying and fitting linear models for serial measurements uses methods based on the standard multivariate linear model. This article proposes a more flexible approach that permits specification of the expected response as an arbitrary linear function of fixed and time-varying covariates so that mean-value functions can be derived from subject matter considerations rather than methodological constraints. Three families of models for the covariance function are discussed: multivariate, autoregressive, and random effects. Illustrations demonstrate the flexibility and utility of the proposed approach to longitudinal analysis. 相似文献
53.
The unweighted sample mean is examined as an estimator of the population mean in a first-order autoregressive model. It is demonstrated that the precision of this estimator deteriorates as the number of equally spaced observations taken within a fixed time interval increases. 相似文献
54.
At a data analysis exposition sponsored by the Section on Statistical Graphics of the ASA in 1988, 15 groups of statisticians analyzed the same data about salaries of major league baseball players. By examining what they did, what worked, and what failed, we can begin to learn about the relative strengths and weaknesses of different approaches to analyzing data. The data are rich in difficulties. They require reexpression, contain errors and outliers, and exhibit nonlinear relationships. They thus pose a realistic challenge to the variety of data analysis techniques used. The analysis groups chose a wide range of model-fitting methods, including regression, principal components, factor analysis, time series, and CART. We thus have an effective framework for comparing these approaches so that we can learn more about them. Our examination shows that approaches commonly identified with Exploratory Data Analysis are substantially more effective at revealing the underlying patterns in the data and at building parsimonious, understandable models that fit the data well. We also find that common data displays, when applied carefully, are often sufficient for even complex analyses such as this. 相似文献
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56.
Paul H. Whitfield 《统计学通讯:模拟与计算》2013,42(10):3008-3030
ABSTRACTIn a changing climate, changes in timing of seasonal events such as floods and flowering should be assessed using circular methods. Six different methods for clustering on a circle and one linear method are compared across different locations, spreads, and sample sizes. Best results are obtained when clusters are well separated and the number of observations in each cluster is approximately equal. Simulations of flood-like distributions are used to assess and explore clustering methods. Generally, k-means provides results that are close to the expected results, some other methods perform well under specific conditions, but no single method is exemplary. 相似文献
57.
A well-known procedure for the optimization of a second-degree response function over a spherical region of interest is that of ridge analysis. Khuri and Myers (1979) introduced a modification of this procedure by incorporating a certain constraint on the prediction variance. Both procedures, however, assume that the response variable has a constant variance throughtout the experimental region. In the present article, we consider two extensions to Khuri and Myers modifioed ridge analysis. The first extension relaxes the constant variance assumption. In the second extension. generalised linear models are used instead of the trasitional linear model. which are commenly used in responce variables that are not necessaily continusly distribution, including these have discreate distributions, Two examples are presented to illustrate the implementation of the proposed extensions. 相似文献
58.
We consider the square contingency tables which arise when the same method of classification is applied twice. The hypothesis of marginal homogeneity is then relevant! and can be tested by various methods Models are discussed which contain marginal homogeneity as a special case. They include a class based on univariate and bivariate Dirichlet distributions. The question of ordered categories is briefly discussed. Applications are made to data on unaided distance vision. 相似文献
59.
Paul K.H. Lin 《统计学通讯:理论与方法》2013,42(2):407-419
This paper presents the sinplesr procedure that uses wodular aryithmetic for constructing confounded designs for mixed factorial experiments. The present procedure and the classical one for confounding in symmetrical factorial experiments are both at the same mathema.tical level. The present procedure is written for practitioners and is lllustrared with several examples. 相似文献
60.
Paul K.H.Lin 《统计学通讯:理论与方法》2013,42(2):421-429
The derivation of a simpie mexhoa for confounding in mixed factorial experiments from an isomorphism of finite abelian groups is presented. The theoretical bases of confounding procedures that use modular arithmetic for such experiments are compared. 相似文献