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551.
Assessment following serious child abuse is a significant activity for the social work, psychology and psychiatric professions. Notwithstanding the profound significance of the consequences for abused children and their families from recommendations made by such assessments, there is little research which examines the process and outcome of child protection assessments. This paper describes the professional practice principles of an independent assessment team and presents preliminary findings from a retrospective examination of 160 major independent assessments undertaken over a period of 11 years. The review suggests that nearly 60% of the families gained some therapeutic benefit from the assessment process and outlines the areas in which such benefits occurred. It is argued that structuring assessments in a way which maximizes the possibility of parents/carers effecting changes in problem areas is the essence of a constructive partnership relation with families. Copyright © 1999 John Wiley & Sons, Ltd.  相似文献   
552.
553.
In longitudinal biomedical studies, there is often interest in the rate functions, which describe the functional rates of change of biomarker profiles. This paper proposes a semiparametric approach to model these functions as the realizations of stochastic processes defined by stochastic differential equations. These processes are dependent on the covariates of interest and vary around a specified parametric function. An efficient Markov chain Monte Carlo algorithm is developed for inference. The proposed method is compared with several existing methods in terms of goodness-of-fit and more importantly the ability to forecast future functional data in a simulation study. The proposed methodology is applied to prostate-specific antigen profiles for illustration. Supplementary materials for this paper are available online.  相似文献   
554.
Robust variable selection with application to quality of life research   总被引:1,自引:0,他引:1  
A large database containing socioeconomic data from 60 communities in Austria and Germany has been built, stemming from 18,000 citizens’ responses to a survey, together with data from official statistical institutes about these communities. This paper describes a procedure for extracting a small set of explanatory variables to explain response variables such as the cognition of quality of life. For better interpretability, the set of explanatory variables needs to be very small and the dependencies among the selected variables need to be low. Due to possible inhomogeneities within the data set, it is further required that the solution is robust to outliers and deviating points. In order to achieve these goals, a robust model selection method, combined with a strategy to reduce the number of selected predictor variables to a necessary minimum, is developed. In addition, this context-sensitive method is applied to obtain responsible factors describing quality of life in communities.  相似文献   
555.
The use of surrogate variables has been proposed as a means to capture, for a given observed set of data, sources driving the dependency structure among high-dimensional sets of features and remove the effects of those sources and their potential negative impact on simultaneous inference. In this article we illustrate the potential effects of latent variables on testing dependence and the resulting impact on multiple inference, we briefly review the method of surrogate variable analysis proposed by Leek and Storey (PNAS 2008; 105:18718-18723), and assess that method via simulations intended to mimic the complexity of feature dependence observed in real-world microarray data. The method is also assessed via application to a recent Merck microarray data set. Both simulation and case study results indicate that surrogate variable analysis can offer a viable strategy for tackling the multiple testing dependence problem when the features follow a potentially complex correlation structure, yielding improvements in the variability of false positive rates and increases in power.  相似文献   
556.
We introduce health technology assessment and evidence synthesis briefly, and then concentrate on the statistical approaches used for conducting network meta-analysis (NMA) in the development and approval of new health technologies. NMA is an extension of standard meta-analysis where indirect as well as direct information is combined and can be seen as similar to the analysis of incomplete-block designs. We illustrate it with an example involving three treatments, using fixed-effects and random-effects models, and using frequentist and Bayesian approaches. As most statisticians in the pharmaceutical industry are familiar with SAS? software for analyzing clinical trials, we provide example code for each of the methods we illustrate. One issue that has been overlooked in the literature is the choice of constraints applied to random effects, and we show how this affects the estimates and standard errors and propose a symmetric set of constraints that is equivalent to most current practice. Finally, we discuss the role of statisticians in planning and carrying out NMAs and the strategy for dealing with important issues such as heterogeneity.  相似文献   
557.
This paper seeks to add to the literature on working with fathers by focusing on early intervention. It draws on research into fathers involved in a home visitation service delivered by the Family Nurse Partnership in England and evaluates the men's experiences of the intervention. The vulnerability of fathers was striking and many were helped to develop their practical skills and confidence in caring for their babies. The intervention was effective because of the quality time that was invested in developing relationships with fathers (as well as mothers), the focus on their strengths as well as areas for improvement and the skilled, therapeutically oriented, holistic approach through which the service was delivered. The ‘early’ nature of the help was crucial to its success because of how it so effectively tapped into the men's redefinition of themselves as caring fathers during pregnancy and following the birth. We argue that there is important learning here for social care and health services in general about how to engage men and promote fathers' capacities to care for their children.  相似文献   
558.
This paper begins by examining the social inclusion agenda that formed the centrepiece of the social policy agenda of the Australian Government between 2007 and 2013. It discusses several features of the agenda, including its objectives (as articulated by the government) and some of the administrative and bureaucratic mechanisms that were put in place to assist with its development and implementation. Although no formal assessment of the impact of the agenda is attempted, some of the ways in which such an agenda could make a difference are identified. The paper then summarises the social inclusion indicator framework developed by the Australian Social Inclusion Unit with assistance and advice from the Australian Social Inclusion Board, and compares its structure and content with the frameworks developed by two of Australia's leading social research institutes. Finally, data from two national surveys of poverty and social exclusion are used to examine recent changes in social exclusion and the association between the severity of exclusion and levels of subjective well‐being. These latter results show clearly that subjective well‐being is consistently lower among those who experience the greatest degree of social exclusion, suggesting that exclusion as identified and measured reflects external constraints rather than internal preferences.  相似文献   
559.
Deprivation and Poverty in Hong Kong   总被引:1,自引:0,他引:1  
Despite high and rising real incomes, the poverty rate in Hong Kong remains a cause of community concern. The government has been reluctant to set a poverty line, although the recently (re‐)established Commission on Poverty has recommended that a poverty line for Hong Kong is developed. Against this background, this article reports results derived from a new deprivation study designed to shed new light on the living standards of the poorest in the community. Reflecting international studies, deprivation is identified as existing when people do not have and cannot afford items regarded by a majority in the community as being essential for all. A list of 35 basic needs items is identified as meeting this definition, the results indicating that around 30 per cent are deprived of at least two items, over 18 per cent are deprived of at least four items and 10 per cent are deprived of at least eight items. Deprivation rates are particularly high among items that meet basic health needs. A mean deprivation score index (MDIS) is then used to compare the degree of deprivation experienced by different groups, and indicates that deprivation is most pronounced amongst those receiving Comprehensive Social Security Assistance (CSSA), people affected by a disability and recent migrants. The overlap between deprivation and income poverty is also relatively low, which suggests both measures have a role to play in identifying who is most vulnerable and guiding where policy change is most urgently needed.  相似文献   
560.
This paper reviews interventions for preventing the occurrence and recurrence of major types of child maltreatment. We begin with an overview of the challenges of establishing evidence‐based interventions to prevent child abuse and neglect in many countries, and underscore the importance of this need with child maltreatment incidence rates in the USA, and how much each type and subtype contribute to child out‐of‐home placement. Next, we identify the well‐supported, supported and promising interventions for each child maltreatment type and subtype, according to their level of research evidence using an evidence‐based clearing house. The paper closes with a discussion of the implications for practice, evaluation, policy and agency management, including intervention knowledge gaps that showcase areas that need additional practice research.  相似文献   
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