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121.
Specific efficacy criteria were defined by the International Headache Society for controlled clinical trials on acute migraine. They are derived from the pain profile and the timing of rescue medication intake. We present a methodology to improve the analysis of such trials. Instead of analysing each endpoint separately, we model the joint distribution and derive success rates in any criteria as predictions. We use cumulative regression models for each response at a time and a multivariate normal copula to model the dependence between responses. Parameters are estimated using maximum likelihood. Benefits of the method include a reduction in the number of tests performed and an increase in their power. The method is well suited to dose–response trials from which predictions can be used to select doses and optimize the design of subsequent trials. More generally, our method permits a very flexible modelling of longitudinal series of ordinal data. Copyright © 2003 John Wiley & Sons, Ltd.  相似文献   
122.
We analyze the optimal choices of agents with utility functions whose derivatives alternate in sign, an important class that includes most of the functions commonly used in economics and finance (Mixed Risk Aversion, MRA, Caballé and Pomansky, 1996). We propose a comparative mixed risk aversion definition for this class of utility functions, namely, More Risk Averse MRA, and provide a sufficient condition to compare individuals. We apply the model to optimal prevention and willingness to pay. More risk averse MRA agents spend less to reduce accident probabilities that are above 1/2. They spend more only when accident probabilities are below 1/2. Explanations in terms of risk premiums are provided. The results presented also allow for the presence of background risk.  相似文献   
123.
The paper presents some results obtained in searching for a new axiomatic foundation for partial comparability (PC) in the frame of non-conventional preference modeling. The basic idea is to define an extended preference structure able to represent lack of information, uncertainty, ambiguity, multidimensional and conflicting preferences, using formal logic as the basic formalism.A four-valued paraconsistent logic is therefore described in the paper as a more suitable language for the purposes of the research. The concepts of partition, general binary relations properties, fundamental relational system of preferences (f.r.s.p.), maximal f.r.s.p. and well founded f.r.s.p. are then introduced and some theorems are demonstrated in order to provide the axiomatic foundation of PC. The main result obtained is a preference structure that is a maximal well founded f.r.s.p. This preference structure facilitates a more flexible, reliable and robust preference modeling. Moreover it can be viewed as a generalization of the conventional approach, so that all the results obtained until now can be used under it.Two examples are provided at the end of the paper in order to give an account of the operational potentialities of the new theory, mainly in the area of multicriteria decision aid and social choice theory. Further research directions conclude the paper.This research has been done while the first author was in the Université Libre de Bruxelles under the Research in Brussels actions.  相似文献   
124.
Non-profit human service organizations, both public and private, face unique challenges and opportunities in the climate of the 1990s as human needs are increasing, funding is decreasing, and threats to organizational well-being are encountered. The purpose of this paper is to describe, advocate for, and illustrate a strategic planning model which facilitates a proactive, energizing, futuristic vision as services are being planned and delivered. Three case examples are used: a large state-run county social services department; a small, private, sectarian agency that provides group home services for the developmentally disabled; and a medium sized federal public health hospital.  相似文献   
125.
Divorce can be a distressing event. Although various studies have been conducted to better understand this phenomenon, little research has focused on the combined effect of age, initiator status, spousal infidelity, and spiritual well-being on divorce adjustment. To determine the effect of these 4 factors on divorce adjustment, 133 divorced women in the United States were surveyed using the Fisher Divorce Adjustment Scale, Spiritual Well-Being Scale, and a participant questionnaire. Results indicate that initiator status, spousal infidelity, and spiritual well-being together can predict 38% of the variance in overall divorce adjustment for women. Spiritual well-being was found to be the strongest contributor. Recommendations for researchers and implications for clinicians are discussed.  相似文献   
126.
ABSTRACT

This research investigates the relationship between concern over terrorism and negative attitudes toward unauthorized immigration before and after the 9/11 terrorist attacks. A hierarchical age-period-cohort analysis was conducted using nationally representative cross-sectional data to take into account macro-level influences on individual attitudes. Results suggest that concern over terrorism is positively related to negative attitudes toward immigration. Further, the relationship between concern over terrorism and negative attitudes toward unauthorized immigration became stronger in the decade following the 9/11 attacks. However, the findings do not support the hypothesis that 9/11 directly increased negative attitudes toward immigration.  相似文献   
127.
Focusing on the era of the Haitian Revolution, this article analyses recent historiographical developments in both French and English. Though the field has made great strides in recent decades, it occasionally remains hampered by insufficient archival research, a parochial approach by US and French scholars, and linguistic fragmentation. The article also includes a survey of the main archival resources that are available to scholars in Europe, the Caribbean, and the USA.  相似文献   
128.
The issue of how one school of social work in the United States approached the systematic incorporation of racial/ethnic and gender-related content in its curriculum is the subject of this paper. American accreditation standards on curriculum content of the above issues are discussed, as are the impact of this process on the school's curriculum as well as increased faculty awareness.  相似文献   
129.
130.

We consider cooperatives games (TU-games) enriched by a system of a priori unions and a communication forest graph which are independent from each other. These two structures reflect the limitations of cooperation possibilities. In this framework, we introduce four Owen-type allocation rules, which are defined by a two-step application of an allocation rule à la Owen (in: Henn R, Moeschlin O (eds) Essays in mathematical economics and game theory, Springer, Berlin, 1977) to TU-games with a priori unions where the TU-game is replaced by Myerson’s (Math Oper Res 2:225–229, 1977) graph-restricted TU-game. The four possibilities arise by applying, at each step, either the Myerson value (Myerson 1977) or the average tree solution (Herings et al. in Games Econ Behav 62:77–92, 2008). Our main result offers comparable axiomatizations of these four allocation rules.

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