HEAPING‐INDUCED BIAS IN REGRESSION‐DISCONTINUITY DESIGNS

This study uses Monte Carlo simulations to demonstrate that regression‐discontinuity designs arrive at biased estimates when attributes related to outcomes predict heaping in the running variable. After showing that our usual diagnostics may not be well suited to identifying this type of problem, we provide alternatives, and then discuss the usefulness of different approaches to addressing the bias. We then consider these issues in multiple non‐simulated environments. (JEL C21, C14, I12)     

Credit at the Corner Store: An Analysis of Resource Exchange among Detroit‐Area Urban Poor

This ethnographic study examines how and why Detroit‐area credit‐constrained members of the urban poor relied on owners/employees of corner convenience stores, known as “party stores,” for accessing short‐term, interest‐free informal credit services. Findings indicate that informal credit at party stores functioned as a low‐ or no‐cost alternative to formal credit and high‐cost fringe banking services such as payday loans, both of which were inaccessible and/or cost prohibitive for informants. These data contribute empirically to a growing body of research on “credit invisibility” by exploring these populations' use of informal credit mechanisms. Findings also make a theoretical contribution by highlighting the importance of resource exchange networks through which members of the urban poor build strong yet disposable social ties in order to respond to economic shocks, combat food insufficiency, and survive economic destitution.     

Individual Therapy for Couple Problems: Perspectives and Pitfalls

Despite the demonstrated efficacy of conjoint couple therapy, many clients seeking help for couple problems ultimately find themselves in individual therapy for these concerns. Individual therapy for couple problems (ITCP) may evolve from a partner's refusal of conjoint therapy or from the treatment format preferences of either the client or therapist. Having acknowledged the role of partner refusals, we offer some perspectives about the idiosyncratic personal factors and professional background factors that may lead therapists to provide ITCP and discuss the significant pitfalls in its practice. We emphasize five central areas of concern in the ongoing practice of ITCP: structural constraints on change; therapist side‐taking and the therapeutic alliance; inaccurate assessments based on individual client reports; therapeutic focus; and ethical issues relevant to both attending and nonattending partners. We conclude by urging that this very important but largely neglected topic be paid greater attention in psychotherapy research, training and continuing education.     

An adaptive biomarker basket design in phase II oncology trials

The phase II basket trial in oncology is a novel design that enables the simultaneous assessment of treatment effects of one anti-cancer targeted agent in multiple cancer types. Biomarkers could potentially associate with the clinical outcomes and re-define clinically meaningful treatment effects. It is therefore natural to develop a biomarker-based basket design to allow the prospective enrichment of the trials with the adaptive selection of the biomarker-positive (BM+) subjects who are most sensitive to the experimental treatment. We propose a two-stage phase II adaptive biomarker basket (ABB) design based on a potential predictive biomarker measured on a continuous scale. At Stage 1, the design incorporates a biomarker cutoff estimation procedure via a hierarchical Bayesian model with biomarker as a covariate (HBMbc). At Stage 2, the design enrolls only BM+ subjects, defined as those with the biomarker values exceeding the biomarker cutoff within each cancer type, and subsequently assesses the early efficacy and/or futility stopping through the pre-defined interim analyses. At the end of the trial, the response rate of all BM+ subjects for each cancer type can guide drug development, while the data from all subjects can be used to further model the relationship between the biomarker value and the clinical outcome for potential future research. The extensive simulation studies show that the ABB design could produce a good estimate of the biomarker cutoff to select BM+ subjects with high accuracy and could outperform the existing phase II basket biomarker cutoff design under various scenarios.     

Likelihood testing populations modeled by autoregressive process subject to the limit of detection in applications to longitudinal biomedical data

Dependent and often incomplete outcomes are commonly found in longitudinal biomedical studies. We develop a likelihood function, which implements the autoregressive process of outcomes, incorporating the limit of detection problem and the probability of drop-out. The proposed approach incorporates the characteristics of the longitudinal data in biomedical research allowing us to carry out powerful tests to detect a difference between study populations in terms of the growth rate and drop-out rate. The formal notation of the likelihood function is developed, making it possible to adapt the proposed method easily for various different scenarios in terms of the number of groups to compare and a variety of growth trend patterns. Useful inferential properties for the proposed method are established, which take advantage of many well-developed theorems regarding the likelihood approach. A broad Monte-Carlo study confirms both the asymptotic results and illustrates good power properties of the proposed method. We apply the proposed method to three data sets obtained from mouse tumor experiments.     

Top Management Team Internationalization and Firm-level Internationalization: The Moderating Effects of Home-region Institutional Diversity and Firm Global Focus

The factors that determine firms' levels of internationalization remain a focal area of international business research. Within this research stream, studies building on the upper echelons theory have investigated the influence of the demographic characteristics of the top management team (TMT) on firms' international expansion. However, the literature to date has overlooked the TMT's overall degree of internationalization as a key driver of firm-level internationalization. In our paper, we argue that by having self-selected into careers abroad, foreign TMT members by definition have a higher cognitive tolerance of foreignness than domestic TMT members do. We theorize that foreign TMT members' higher cognitive tolerance for foreignness enhances the overall TMT's level of international attention and international trust, thereby facilitating strategic decisions that favor firm-level internationalization. Additionally, we propose two key contingencies that attenuate this relationship: the institutional diversity of the firm's home region and the firm's global focus. Analysis of Fortune Global 500 firms supports the hypothesized relationship between TMT internationalization and firm-level internationalization, as well as the two moderation effects.     

Experiential Wellbeing Data from the American Time Use Survey: Comparisons with Other Methods and Analytic Illustrations with Age and Income

There has been a recent upsurge of interest in self-reported measures of wellbeing by official statisticians and by researchers in the social sciences. This paper considers data from a wellbeing supplement to the American Time Use Survey (ATUS), which parsed the previous day into episodes. Respondents provided ratings of five experiential wellbeing adjectives (happiness, stress, tiredness, sadness, and pain) for each of three randomly selected episodes. Because the ATUS wellbeing module has not received very much attention, in this paper we provide the reader with details about the features of these data and our approach to analyzing the data (e.g., weighting considerations), and then illustrate the applicability of these data to current issues. Specifically, we examine the association of age and income with all of the experiential wellbeing adjective in the ATUS. Results from the ATUS wellbeing module were broadly consistent with earlier findings on age, but did not confirm all earlier findings between income and wellbeing. We conclude that the ATUS, with its measurement of time use, specific activities, and hedonic experience in a nationally representative survey, offers a unique opportunity to incorporate time use into the burgeoning field of wellbeing research.     

Welfare Recipients or Workers? Contesting the Workfare State in New York City

This paper addresses how New York City's workfare program has structured opportunities for collective action by welfare recipients. As workfare blurs the distinction between wage workers and welfare recipients, it calls into question accepted understandings of the rights and obligations of welfare recipients and fosters new claims on the state. The concept of "cultural opportunity structures" can help to explain the political mobilization of workfare participants if it is linked to a Durkheimian tradition of cultural analysis attentive to symbolic classification. The dramaturgic approach to culture exemplified in the work of Erving Goffman can usefully complement this structural approach if a narrow focus on frames and framing processes is broadened to include interaction rituals and ceremonial profanation.