Discovering classes in microarray data using island counts

We present a new biclustering algorithm to simultaneously discover tissue classes and identify a set of genes that well-characterize these classes from DNA microarray data sets. We employ a combinatorial optimization approach where the object is to simultaneously identify an interesting set of genes and a partition of the array samples that optimizes a certain score based on a novel color island statistic. While this optimization problem is NP-complete in general, we are effectively able to solve problems of interest to optimality using a branch-and-bound algorithm. We have tested the algorithm on a 30 sample Cutaneous T-cell Lymphoma data set; it was able to almost perfectly discriminate short-term survivors from long-term survivors and normal controls. Another useful feature of our method is that can easily handle missing expression data.     

Editorial

Ohne Zusammenfassung

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Editorial

     

Ebert. Wolfgang (2001): Systemtheorien in der Supervision — Bestandsaufnahme und Perspektiven

Ohne Zusammenfassung     

Supervision als Fortbildungsangebot für stellvertretende schulleiter

Supervision as further education of vice-headmasters Our offer of further education aims at an improvement of executive activities of viceheadmasters. With the help of their first experiences with our concept they’ll become acquainted with the various processes of change in schools and can use it as an opportunity to support them. That’s our contribution to the development of the executive personnel in the schools of Sachsen-Anhalt.     

布莱克─肖尔斯期权定价模型在公司价值评估中的应用

公司股票、债券在本质上可看成是基于公司资产的期权,因而可用期权定价方法对其价值进行评估。本文介绍了最典型的期权定价模型─布莱克一肖尔斯期权定价模型,分析了该模型在公司证券价值评估中的应用。     

大学生优秀典型作用研究

抓好用好典型，通过典型示范和引领激励，以点带面推动全局工作，历来是我党的优良传统，也是一门重要的领导艺术和行之有效的工作方法。针对新时期大学生思想道德变化的特点，研究在大学生中树立并大力宣传优秀典型，明确树立大学生优秀典型的意义和作用，探索树立大学生先进典型的具体方法，对于准确地把握大学生思想政治工作面临的新形势，构建新格局，提高高校学生思想政治工作的针对性、实效性和科学性具有十分重要的作用和意义。     

湖南省普通高等教育产品专业差异化定价问题

专业差异化定价是高等教育产品差异化定价的一种实施策略,对于有效发挥收费在维系消费公平、配置教育资源及解决市场失灵方面意义重大.现行湖南省高等教育分专业定价中存在着成本依据不清晰、分类标准存误区及实施效应不明显等缺陷,需要在科学制订政府指导价的前提下,通过对不同专业实际生均成本的测算,依据不同思路分别制定"热门"与"冷门"、基础学科与应用学科不同专业的价格基准差及定价策略.     

Young Adult Gambling Behaviors and their Relationship with the Persistence of ADHD

Young adulthood is a period renowned for engagement in impulsive and risky behaviors, including gambling. There are some indications that young adults exhibit higher gambling rates in comparison to older adults. Problem gambling has also been linked to ADHD. This longitudinal study examines the relationship between gambling and ADHD among an epidemiological sample of young adults (n = 235; males = 179, females = 56) aged 18-24. Results indicate that individuals who report childhood ADHD symptoms which persist into young adulthood experience greater gambling problem severity than participants with no ADHD or those with non-persistent ADHD.