A generalization of the compound rayleigh distribution: using a bayesian method on cancer survival times

In this paper the generalized compound Rayleigh model, exhibiting flexible hazard rate, is high¬lighted. This makes it attractive for modelling survival times of patients showing characteristics of a random hazard rate. The Bayes estimators are derived for the parameters of this model and some survival time parameters from a right censored sample. This is done with respect to conjugate and discrete priors on the parameters of this model, under the squared error loss function, Varian's asymmetric linear-exponential (linex) loss function and a weighted linex loss function. The future survival time of a patient is estimated under these loss functions. A Monte Carlo simu¬lation procedure is used where closed form expressions of the estimators cannot be obtained. An example illustrates the proposed estimators for this model.     

Contraceptive Responsibility among Male University Students

Abstract

This paper assesses the male contribution to contraceptive mismanagement and unwanted pregnancy. The subjects were 109 students at the University of Melbourne. A high incidence of risk-taking was reported, and almost one-fifth of the sexually experienced men stated that they had been involved in an unwanted pregnancy. A small group of these reported more than one such incident. The underlying reasons for poor contraceptive technique seemed to be related to two beliefs: that contraception is a female responsibility, and that sexual intercourse should be entirely spontaneous and unplanned.     

Human Health Risk Assessment of Penicillin/Aminopenicillin Resistance in Enterococci Due to Penicillin Use in Food Animals

Penicillin and ampicillin drugs are approved for use in food animals in the United States to treat, control, and prevent diseases, and penicillin is approved for use to improve growth rates in pigs and poultry. This article considers the possibility that such uses might increase the incidence of ampicillin-resistant Enterococcus faecium (AREF) of animal origin in human infections, leading to increased hospitalization and mortality due to reduced response to ampicillin or penicillin. We assess the risks from continued use of penicillin-based drugs in food animals in the United States, using several assumptions to overcome current scientific uncertainties and data gaps. Multiplying the total at-risk population of intensive care unit (ICU) patients by a series of estimated factors suggests that not more than 0.04 excess mortalities per year (under conservative assumptions) to 0.14 excess mortalities per year (under very conservative assumptions) might be prevented in the whole U.S. population if current use of penicillin drugs in food animals were discontinued and if this successfully reduced the prevalence of AREF infections among ICU patients. These calculations suggest that current penicillin usage in food animals in the United States presents very low (possibly zero) human health risks.     

An assessment of GRAI Grids and their use in the Strathclyde Integration Method

The purpose of this paper is to present a critical assessment of GRAI Grids as a tool for improved manufacturing integration. GRAI Grids, a key component of the GRAI approach, form an integral part of the Strathclyde Integration Method SIM for manufacturing integration. The contribution of the paper is thus to provide a 'third party' view of the effectiveness of GRAI Grids as a modelling tool. The paper presents a brief overview of the GRAI approach, concentrating particularly on the Grids, and an overview of SIM, showing how GRAI Grids are used. The main section of the paper presents an assessment and critique of GRAI Grids. Several benefits and limitations of the Grid as used in SIM and some suggestions for extensions are presented. The paper concludes that the use of the GRAI Grid, within a methodology, provides a unique insight into the behaviour and design of manufacturing information systems and that those who criticize the technique perhaps do so from a lack of awareness of its concepts, principles and advantages.     

Approaches to the Fertility Transition in Victorian England

The secular decline of marital fertility which took place in late nineteenth and early twentieth-century England and Wales is considered by using a number of approaches. Among the theoretical approaches considered are those of transition models, and social diffusion. The former overemphasises the role of industrialization and urbanization; the latter is inappropriate when dealing with the development of a small-family ideal in Victorian society. Explanations of fertility decline using ecological and time-series analysis are considered. The registration districts of England and Wales provide the framework for analyses of spatial variations in marital fertility and its correlates in 1861, 1891 and 1911. A time-series analysis attempts to establish the sequential nature of social, economic and demographic changes during the sixty years preceding the First World War. The following points are emphasised in conclusion. The Victorian fertility transition was not directly related to the development of an urban-industrial society, the social diffusion of family ideals or the use of appliance methods of contraception. But its immediate cause was probably linked to the substantial increase in family planning literature available from the 1870s, and the challenge that this posed to the tradition of unlimited marital fertility. This critical change in social attitudes to family planning was facilitated both by developments in mass education and, ultimately by the decline of infant mortality.     

Is Valuing Equality Enough? Equality Values, Allophilia, and Social Policy Support for Multiracial Individuals

We conducted a field study to investigate positive intergroup attitudes (i.e., allophilia) and equality values as potential antecedents of social policy support for multiracial individuals. Participants (N = 97) reported their social policy support for multiracial individuals in two ways—support for the recognition of "multiracial" as a distinct racial category (recognition) and support for multiracial individuals' access to programs and policies (assistance). Results revealed that allophilia motivated those who held equality beliefs to support social policies for multiracial individuals. Implications of these findings for theories of positive intergroup relations, as well as the processes that may underlie progress for multiracial individuals, are discussed.     

Pandemic Recovery Analysis Using the Dynamic Inoperability Input-Output Model

Economists have long conceptualized and modeled the inherent interdependent relationships among different sectors of the economy. This concept paved the way for input-output modeling, a methodology that accounts for sector interdependencies governing the magnitude and extent of ripple effects due to changes in the economic structure of a region or nation. Recent extensions to input-output modeling have enhanced the model's capabilities to account for the impact of an economic perturbation; two such examples are the inoperability input-output model^{( 1 , 2 )} and the dynamic inoperability input-output model (DIIM).^{( 3 )} These models introduced sector inoperability, or the inability to satisfy as-planned production levels, into input-output modeling. While these models provide insights for understanding the impacts of inoperability, there are several aspects of the current formulation that do not account for complexities associated with certain disasters, such as a pandemic. This article proposes further enhancements to the DIIM to account for economic productivity losses resulting primarily from workforce disruptions. A pandemic is a unique disaster because the majority of its direct impacts are workforce related. The article develops a modeling framework to account for workforce inoperability and recovery factors. The proposed workforce-explicit enhancements to the DIIM are demonstrated in a case study to simulate a pandemic scenario in the Commonwealth of Virginia.     

Predicting infectious disease outbreak risk via migratory waterfowl vectors

The spread of an emerging infectious disease is a major public health threat. Given the uncertainties associated with vector-borne diseases, in terms of vector dynamics and disease transmission, it is critical to develop statistical models that address how and when such an infectious disease could spread throughout a region such as the USA. This paper considers a spatio-temporal statistical model for how an infectious disease could be carried into the USA by migratory waterfowl vectors during their seasonal migration and, ultimately, the risk of transmission of such a disease to domestic fowl. Modeling spatio-temporal data of this type is inherently difficult given the uncertainty associated with observations, complexity of the dynamics, high dimensionality of the underlying process, and the presence of excessive zeros. In particular, the spatio-temporal dynamics of the waterfowl migration are developed by way of a two-tiered functional temporal and spatial dimension reduction procedure that captures spatial and seasonal trends, as well as regional dynamics. Furthermore, the model relates the migration to a population of poultry farms that are known to be susceptible to such diseases, and is one of the possible avenues toward transmission to domestic poultry and humans. The result is a predictive distribution of those counties containing poultry farms that are at the greatest risk of having the infectious disease infiltrate their flocks assuming that the migratory population was infected. The model naturally fits into the hierarchical Bayesian framework.     

The burdens of social capital: How socially-involved people dealt with stress after Hurricane Katrina

Research shows that those with greater social capital enjoy better physical and mental health. The current study illuminates a paradox of social capital which may afflict those involved in traumatic events. Several years of survey data reveal a dynamic picture of the link between social capital and stress following Hurricane Katrina. Results reveal that initially after Katrina, those who were more socially embedded carried the greatest load with respect to helping the displaced population, thus experiencing more stress. But over time, the most socially-involved then snapped back from their stressful experiences more rapidly than isolates. This confirms that over the course of stressful events, social involvement first exposes people to more stress, but as time passes, provides them a significant buffer against negative psychosocial experiences.