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91.
92.
The Points to Consider Document on Missing Data was adopted by the Committee of Health and Medicinal Products (CHMP) in December 2001. In September 2007 the CHMP issued a recommendation to review the document, with particular emphasis on summarizing and critically appraising the pattern of drop‐outs, explaining the role and limitations of the ‘last observation carried forward’ method and describing the CHMP's cautionary stance on the use of mixed models. In preparation for the release of the updated guidance document, statisticians in the Pharmaceutical Industry held a one‐day expert group meeting in September 2008. Topics that were debated included minimizing the extent of missing data and understanding the missing data mechanism, defining the principles for handling missing data and understanding the assumptions underlying different analysis methods. A clear message from the meeting was that at present, biostatisticians tend only to react to missing data. Limited pro‐active planning is undertaken when designing clinical trials. Missing data mechanisms for a trial need to be considered during the planning phase and the impact on the objectives assessed. Another area for improvement is in the understanding of the pattern of missing data observed during a trial and thus the missing data mechanism via the plotting of data; for example, use of Kaplan–Meier curves looking at time to withdrawal. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
93.
Chicago has put in place a number of interwoven structures supporting young people during out-of-school hours, emphasizing alignment between community-based organizations and public entities.  相似文献   
94.
This paper, a plenary address to the Australian Family Therapy Conference, is concerned with the role of family therapy in society and the abuse of professional power. It is argued that family therapy is part of the medicalisation of marriage and the family, through which problems are definedoften inappropriatelyas relationship problems and experts (therapists) are created. Aspects of professional power are identified; its pursuit is not in the interests of families, especially those with greatest needs. Proposals to tackle these obstacles are made regarding practice and training in therapy, and the management of professional power.  相似文献   
95.
Correspondence to Professor John Carpenter, Director, Centre for Applied Social Studies, University of Durham, Elvet Riverside II, Durham DH1 3JT, UK. E-mail: J.S.W.Carpenter{at}dur.ac.ukJ.S.W.Carpenter@dur.ac.uk Summary We report the experiences of different models of community careof random samples of 262 people with severe and enduring mentalhealth problems living in four districts in the north of England.The districts were characterized in terms of the extent of (1)integration between the health service-led Care Programme Approach(CPA) and social services Care Management, and (2) targetingof services on people with severe mental health problems. Themajority of service users felt involved in planning their owncare and considered that they had choice in their care and treatmentwhen in the community, but not in hospital. Although all theseusers were formally subject to the CPA, the proportions of usersin the districts believing they had a written care programmeranged between 37 per cent and 60 per cent. Of these, the greatmajority were very positive about their care programmes andfelt that they were being helped to become independent. Theseresults were replicated when 87 per cent of the original samplewas re-interviewed six months later. There were significantdifferences between the four districts and evidence that userspreferred an integrated health and social care service. In addition,a higher proportion of users in inclusive districts were satisfiedcompared to those in targeted districts. Notwithstanding thesepositive findings, there is still considerable room for improvementin relation to the involvement of family carers and the provisionof adequate information about prescribed medication and makingformal complaints.  相似文献   
96.
ABSTRACT

Sexual attraction to children occurs in roughly 3 to 9 percent of the population. However, most knowledge about such desires comes from forensic samples, and most studies fail to assess preferred sexual activity and sexual partner. A new multimodal assessment of sexual desire was used to investigate interest in consensual and nonconsensual sex with adults and children in an online sample of men sexually attracted to children (n = 101). Desires were compared across history of sex offending behavior and preferred gender of child victim. Men who have and have not acted on their sexual attractions to children reported similar levels of sexual desire. Men primarily attracted to girls reported greater desire for sex with adults than did men primarily attracted to boys. Results highlight the heterogeneity of men sexually attracted to children as well as possible distinctions across gender of children to whom they are primarily attracted.  相似文献   
97.
Theory and research agree that connectedness to the lesbian, gay, bisexual, and transgender (LGBT) community is an important construct to account for in understanding issues related to health and well-being among gay and bisexual men. However, the measurement of this construct among lesbian and bisexual women or racial and ethnic minority individuals has not yet been adequately investigated. This study examined the reliability and validity of an existing measure of connectedness to the LGBT Community among a diverse group of sexual minority individuals in New York City, and whether differences in connectedness existed across gender and race or ethnicity. Scores on the measure demonstrated both internal consistency and construct stability across subgroups defined by gender and race or ethnicity. The subgroups did not differ in their mean levels of connectedness, and scores on the measure demonstrated factorial, convergent, and discriminant validity, both generally and within each of the subgroups. Inconsistencies were observed with regard to which scores on the measure demonstrated predictive validity in their associations with indicators of mental health and well-being. The scale is a useful tool for researchers and practitioners interested in understanding the role of community connectedness in the lives of diverse populations of sexual minority individuals.  相似文献   
98.
Previous research has found that young children recognize an adult as being acquainted with an object most readily when the child and adult have previously engaged socially with that object together. In the current study, we tested the hypothesis that such social engagement is so powerful that it can sometimes lead children to overestimate what has been shared. After having shared two objects with an adult in turn, 2‐year‐old children played with a third object the adult could not see. In three out of four conditions, the adult remained co‐present and/or communicated to the child while she played with the third object. Children falsely perceived the adult as being acquainted with the third object when she remained co‐present (whether or not she also communicated) but not when she clearly terminated the interaction by disengaging and leaving. These results suggest that when young children are engaged with a co‐present person they tend to overestimate the other’s knowledge.  相似文献   
99.
Although many scholars have written about vampire fiction, few have discussed gender and gender violence in this genre. Further, none has addressed the romanticized and eroticized violence in contemporary vampire fiction. Given the popularity of the series The Vampire Diaries and Twilight with a highly impressionable teen audience, it is important to examine their portrayal of gender roles and gender violence. This paper uses research in cultivation theory to highlight the potential impact of messages conveyed in contemporary vampire fiction—focusing on the stereotypical portrayal of men and women, the romanticizing of characteristics predictive of partner abuse, and the link between sex and violence.  相似文献   
100.
The Sexual Inhibition/Sexual Excitation Scales (SIS/SES) assess individual propensities to become sexually aroused and to inhibit arousal. Prior analyses of men's SIS/SES data (Janssen, Vorst, Finn, & Bancroft, 2002a) yielded one excitation factor (SES) and two inhibitory factors (SIS1/Threat of Performance Failure and SIS2/Threat of Performance Consequences). The current study utilized a dataset of 2,045 undergraduates (1,067 women and 978 men) to examine the psychometric properties of women's SIS/SES scores. Women scored higher on sexual inhibition and lower on sexual excitation compared with men. The convergent/discriminant validity of women's SIS/SES scores globally resembled men's, but showed stronger associations with other sexuality - related measures and less pronounced relationships with measures of general behavioral approach/avoidance. The test-retest reliability of men's and women's SIS/SES scores were similar, but individual items exhibited differential relevance to men's and women's arousal. An exploratory factor analysis of women's scores was utilized to further examine shared and unshared themes.  相似文献   
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