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861.
Long- and short-term effects of urban site factors on net N-mineralization and nitrification rates were investigated in oak stands along an urban-rural land-use transect in the New York City metropolitan area. We used reciprocal transplants of undisturbed soil cores between urban and rural forests to determine the relative importance of long-term effects (mor vs. mull soils, quality of soil organic matter, and deposition of N) vs. short-term effects (soil temperature) of urban factors in controlling field N-transformation rates along the gradient. In addition, undisturbed soil cores from surface (A, Oe horizons) and subsurface (B horizon) soil were collected from urban, suburban, and rural stands and allowed to incubate in these respective sites to compare the net effect of all urban factors with transplanted-core results. The transplant experiment revealed that soil type (long-term) affected net N-mineralization and nitrification rates. Urban soils nitrified nearly 6.3 and 5.4 times more than rural soils incubating in urban and rural stands, respectively (p = 0.003 and p = 0.002, respectively). Similarly, in rural stands total accumulation of inorganic N was 87% higher in urban than in rural soils, whereas in urban stands, urban soils mineralized 83% more N than rural soils (p = 0.043 and 0.08, respectively). Comparing soils incubating in their native locations, urban soils incubating in urban stands mineralized more than 2.5 times the amount of N than rural soils incubating in the rural stands (p = 0.019). By contrast, urban soils incubating in urban stands exhibited a 8-fold increase in nitrification over rural soils incubating in rural stands (p = 0.008). As with the transplanted cores, the urban and suburban environments had a positive effect on net rates of N-mineralization and nitrification in both surface and subsurface layers of soil. The surface layer of suburban and urban stands had a 3- and 2.3-fold higher accumulation of net inorganic N than rural stands (ANOVA, p = 0.05). Similarly, in the subsurface layer both urban and suburban stands had 2.6-fold higher net N-mineralization rate than rural stands (ANOVA, p = 0.01). Along this urban-rural gradient, soils in oak stands exhibit higher net nitrification and, to a lesser extent, net N-mineralization rates in urban and suburban stands than in rural stands. Results from the transplant experiment and in situ measurements of surface and subsurface soil indicate that long-term effects (mor vs. mull soils, N deposition) contribute to the higher N-transformation rates in urban and suburban stands. As a result of these effects, urban and suburban stands have the potential for higher losses of N than rural stands. 相似文献
862.
Many syndromes traditionally viewed as individual diseases are heterogeneous in molecular pathogenesis and treatment responsiveness. This often leads to the conduct of large clinical trials to identify small average treatment benefits for heterogeneous groups of patients. Drugs that demonstrate effectiveness in such trials may subsequently be used broadly, resulting in ineffective treatment of many patients. New genomic and proteomic technologies provide powerful tools for the selection of patients likely to benefit from a therapeutic without unacceptable adverse events. In spite of the large literature on developing predictive biomarkers, there is considerable confusion about the development and validation of biomarker-based diagnostic classifiers for treatment selection. In this paper we attempt to clarify some of these issues and to provide guidance on the design of clinical trials for evaluating the clinical utility and robustness of pharmacogenomic classifiers. 相似文献
863.
864.
The terms sweeping and alignment refer to the same process. Sweeping/alignment is used by data analysts as a technique for describing the effects of a model factor (e.g., treatments in a randomized block design) after the effects of nuisance parameters (e.g., blocks) have been removed from the data. In this paper sweeping/alignment is used as the basis for developing tests of factors in unbalanced experimental design models. Formulas are presented for treatment effects in randomized block designs with missing observations, and for interaction and main effects in unbalanced two-way factorial designs with empty cells. 相似文献
865.
Data splitting is the act of partitioning available data into two portions, usually for cross-validatory purposes. One portion of the data is used to develop a predictive model and the other to evaluate the model's performance. This article reviews data splitting in the context of regression. Guidelines for splitting are described, and the merits of predictive assessments derived from data splitting relative to those derived from alternative approaches are discussed. 相似文献
866.
We describe the design and analysis for a simulation experiment to compare the mean-squared errors (MSE's) of two quantile estimators defined for random walk designs. The dependence of the easily computed MSE of the first estimator on the levels of five factors is examined via multiple regression. This information is used to plan a simulation to compute the MSE of the second estimator using a fraction of a 3352factorial allowing uncorrelated estimates for all main effects and the two-factor interactions of a specified factor. Efficient estimation of the MSE of the second estimator is attempted through antithetic and control variate techniques of variance reduction, with modest success. 相似文献
867.
Psychometric Validation of the Gambling Passion Scale (GPS) in an English-speaking University Sample
Bryan A. Castelda Richard E. Mattson James Mackillop Emily J. Anderson Peter J. Donovick 《International Gambling Studies》2013,13(2):173-182
The Gambling Passion Scale (GPS) is a recently developed research instrument for assessing individuals' passion for gambling. Because the psychometric properties of the GPS have only previously been examined in French Canadians, the aim of this study was to replicate previous psychometric findings in an English-speaking university sample. Participants (female: n = 58; male: n = 89) were drawn from a university campus based on self-reported experience with gambling indexed by scores on the South Oaks Gambling Screen (SOGS). The two-factor structure reported by Rousseau et al. (Journal of Gambling Studies, 18(1), pp. 45–66, 2002) was largely replicated in this sample, as were relationships between ‘obsessive passion’ and negative consequences stemming from gambling. These results support the validity of the GPS as a measure of gambling passion in English-speaking university gamblers and its potential to contribute to understanding problem gambling. 相似文献
868.
This is an expository article. Here we show how the successfully used Kalman filter, popular with control engineers and other scientists, can be easily understood by statisticians if we use a Bayesian formulation and some well-known results in multivariate statistics. We also give a simple example illustrating the use of the Kalman filter for quality control work. 相似文献
869.
Richard Enos 《Journal of Social Work Education》2013,49(3):34-41
This study deals with the deployment, utilization, and potential future employment opportunities for bachelor's-level social workers based on a survey of social service agencies in the Dallas-Fort Worth-Denton, Texas metropolitan area. Findings are presented in relation to social service agency reports concerning budgeted and vacant positions for different types of social service personnel, degree and academic fields specified for the positions, estimates concerning future social service personnel positions, preferences in hiring between undifferentiated bachelor's-level personnel and BSWs, and preferences in hiring between BSW and MSW personnel. 相似文献
870.