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71.
In the development of many diseases there are often associated random variables which continuously reflect the progress of a subject towards the final expression of the disease (failure). At any given time these processes, which we call stochastic covariates, may provide information about the current hazard and the remaining time to failure. Likewise, in situations when the specific times of key prior events are not known, such as the time of onset of an occult tumour or the time of infection with HIV-1, it may be possible to identify a stochastic covariate which reveals, indirectly, when the event of interest occurred. The analysis of carcinogenicity trials which involve occult tumours is usually based on the time of death or sacrifice and an indicator of tumour presence for each animal in the experiment. However, the size of an occult tumour observed at the endpoint represents data concerning tumour development which may convey additional information concerning both the tumour incidence rate and the rate of death to which tumour-bearing animals are subject. We develop a stochastic model for tumour growth and suggest different ways in which the effect of this growth on the hazard of failure might be modelled. Using a combined model for tumour growth and additive competing risks of death, we show that if this tumour size information is used, assumptions concerning tumour lethality, the context of observation or multiple sacrifice times are no longer necessary in order to estimate the tumour incidence rate. Parametric estimation based on the method of maximum likelihood is outlined and is applied to simulated data from the combined model. The results of this limited study confirm that use of the stochastic covariate tumour size results in more precise estimation of the incidence rate for occult tumours. 相似文献
72.
In this paper we argue for the importance of a sociologically informed study of organizational accounting practices. By making the nexus between accounting and decision making problematic, instead of given, we move issues of interpretation and hierarchical control to the center stage of understanding the social construction of accounting practices. We suggest that inductive case studies of the organizational setting is a promising methodological strategy for identifying how accounting operates as an organizational control system. We focus on debates and proceedings of the board of directors as an overlooked source of data on decision making and organizational practices. We show how accounting practices are part of the strategic control system that functions to interpret the environment and direct the adaptation of the organization in a manner particular to the substantive rationality of corporate decision makers. We illustrate these contentions with a case study of accounting practice changes over a six year period. 相似文献
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74.
THE INFLUENCE OF ECONOMICS ON ANTITRUST LAW 总被引:1,自引:0,他引:1
WILLIAM E. KOVACIC 《Economic inquiry》1992,30(2):294-306
Economists today play prominent roles in formulating antitrust policy and litigating antitrust cases. This paper explains why economics influences antitrust law and describes how economic theories enter and shape the antitrust system. Antitrust policy and doctrine change over time in response to developments in economic theory, and the decentralization of the antitrust adjudication system and the wide latitude accorded judges in interpreting antitrust statutes ensure that legal rules will reflect advances in the economic literature concerning the appropriate content of standards governing business conduct. 相似文献
75.
The effect of 1980s tort reform legislation on general liability and medical malpractice insurance 总被引:1,自引:1,他引:0
W. Kip Viscusi Richard J. Zeckhauser Patricia Born Glenn Blackmon 《Journal of Risk and Uncertainty》1993,6(2):165-186
A large number of states adopted tort reforms in the mid-1980s to limit the dramatic surge in insurance losses and premiums. Evidence based on liability insurance data by state indicates that these reforms substantially influenced general liability insurance. The levels of losses, premiums, and loss ratios (a measure of insurance profitability) all reflected the impact of the reforms. The large-scale reform efforts in 1986 were particularly influential. Medical malpractice insurance was much less sensitive to the reform efforts. 相似文献
76.
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78.
Richard A. Wright 《The American Sociologist》1995,26(4):41-48
Much debate over the years has centered around whether there was ever a “golden past” for the introductory sociology textbook,
when high quality books influenced the development of scholarship and thinking. Some empirical evidence is added to this debate
through an analysis of the citations to introductory sociology textbooks in all the articles and research notes appearing
in theAmerican Journal of Sociology, theAmerican Sociological Review, andSocial Forces from 1960 to 1969 and from 1984 to 1993. The data show that, although seldom cited in recent journals, introductory sociology
textbooks were often cited in the earlier period. The article concludes with some thoughts about why introductory sociology
textbooks have had a declining influence on scholarship. 相似文献
79.
80.
Rapid advances in sociological computing are changing virtually every aspect of scholarly sociological work. These changes
offer an opportunity for sociologists to improve the quality of their work and bring new insights and approaches to bear on
important sociological problems. Nevertheless, sociologists display a profound ambivalence toward computer work by other sociologists.
Left unchecked, this ambivalence threatens to turn sociological computing into an opportunity missed. Inadequate rewards,
lack of training, and a general failure to understand the importance of computing in sociology threaten to stifle the development
of quality soft-ware, push sociologists competent in computing into other fields, and jeopardize the quality of sociological
scholarship. This article documents these ambivalent tendencies and proposes reasonable steps the discipline should take to
assure that sociological computing does not become an opportunity missed. 相似文献