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Global telecom giant SBC has gotten so big through acquisitions. And, by experience, they have learned the critical systems and processes to whip into operation to make the blend a success. Recognizing the link between business success and strict attention to human resources issues, SBC has formalized guidelines for managers to use throughout the transition process, fostered open communication of change, and determinedly intermingled work groups. © 2001 John Wiley & Sons, Inc.  相似文献   
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  总被引:1,自引:1,他引:0  
We show that contacts in formal, informal and especially multiplex networks explain transfer of innovative knowledge in an organization. The contribution of informal contacts has been much acknowledged, while that of formal contacts did not receive much attention in the literature in recent decades. No study thus far has included both these different kinds of contacts in a firm, let alone considered their combined effect. The exact overlap between formal as well as informal contacts between individuals, forming multiplex or what we call rich ties because of their contribution, especially drives the transfer of new, innovative knowledge in a firm. Studying two cases in very different settings suggests these rich ties have a particularly strong effect on knowledge transfer in an organization, even when controlling for the strength of ties. Some of the effects on knowledge transfer in an organization previously ascribed to either the formal network or the informal network may actually be due to their combined effect in a rich tie.  相似文献   
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This article demonstrates statistical models to quantify the interaction between a carbamate insecticide and acetylcholinesterase. Carbamates are a class of chemicals that inhibit the activity of acetylcholinesterase in humans, an enzyme involved in the regulation of the neurotransmitter acetylcholine. Following exposure to a carbamate insecticide, we specifically address (1) if acetylcholinesterase activity recovers to its level of preexposure activity; (2) the level of inhibition of acetylcholinesterase activity; (3) the recovery time of acetylcholinesterase activity to its preexposure level for a typical individual; and (4) the upper percentiles of the recovery time of acetycholinesterase activity across individuals. A nonlinear mixed-effects model is fitted to data from a repeated measures experiment conducted with human volunteers randomly assigned to a control and four dose groups. Repeated measurements were taken prior to exposure and at 1, 2, 4, 6, 8, and 21 hours after exposure to the carbamate aldicarb. It was found that full recovery did occur. Inhibition at 1 hour was estimated with maximum inhibition most likely occurring prior to 1-hour postexposure. In addition, recovery was rapid even for sensitive individuals. Given this information, the potential effect from exposure to a carbamate consumed in the diet during a day can be quantitatively assessed.  相似文献   
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ABSTRACT

Despite the spectrum of available resources, homelessness is a persistent societal and public health challenge throughout the United States and in San Diego County. Beginning in January 2014, San Diego began the integration of a Coordinated Entry System into its homeless system-of-care. This historical prospective study examined the predictors of establishing eligibility for permanent housing resources among 15,042 single homeless adults enrolled in the Coordinated Entry System Multivariable logistic regression was conducted to assess the relationship between client vulnerability as measured by the triage tool VI-SPDAT and establishing client eligibility for permanent housing. Overall, being of moderate or high vulnerability was associated with establishing eligibility for a permanent housing resource. Veterans established eligibility faster and more frequently than others, regardless of their vulnerability score. However, the demand for services far outweighed the ability of the system to respond to those with moderate to high vulnerability. More housing navigators and fewer client “hand-offs” between housing professionals are recommended to increase the efficiency of the process. Additional research examining the second and third steps is also needed to more fully understand the factors that promote permanent housing solutions for those seeking services.  相似文献   
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Effects of Timing of Adversity on Adolescent and Young Adult Adjustment Abstract Exposure to adversity during childhood and adolescence predicts adjustment across development. Further, adolescent adjustment problems persist into young adulthood. This study examined relations of contextual adversity with concurrent adolescent adjustment and prospective mental health and health outcomes in young adulthood. A longitudinal sample (N = 808) was followed from age 10 through 27. Perceptions of neighborhood in childhood predicted depression, alcohol use disorders, and HIV risk in young adulthood. Further, the timing of adversity was important in determining the type of problem experienced in adulthood. Youth adjustment predicted adult outcomes, and in some cases, mediated the relation between adversity and outcomes. These findings support the importance of adversity in predicting adjustment and elucidate factors that affect outcomes into young adulthood.  相似文献   
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Pleasing patients proves profitable for practices   总被引:2,自引:0,他引:2  
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