SENSITIVITY ANALYSIS WITH INTERACTION EFFECTS

The purpose of this paper is to extend the sensitivity analysis methodology as it applies to linear programming. The methodology developed herein is concerned with those changes in a technological coefficient that cause simultaneous changes in the relevant cost coefficients of the objective function. By proceeding from the definitions of feasibility and optimality, the authors develop formulas for determining bounds on the extent to which a technological coefficient, which has a predetermined effect on the corresponding cost coefficient, can vary without changing the optimal set of activities. After the formulas are developed, their use is demonstrated on a product-mix problem. This technique is of interest because changes in the rate at which an input is utilized can be expected to change the cost per unit of a resulting product. This interdependence should be recognized whenever a sensitivity analysis is performed on a technological coefficient of either a cost minimization or a contribution margin maximization problem.     

A Comparative Pharmacokinetic Estimate of Mercury in U.S. Infants Following Yearly Exposures to Inactivated Influenza Vaccines Containing Thimerosal

The use of thimerosal preservative in childhood vaccines has been largely eliminated over the past decade in the United States because vaccines have been reformulated in single‐dose vials that do not require preservative. An exception is the inactivated influenza vaccines, which are formulated in both multidose vials requiring preservative and preservative‐free single‐dose vials. As part of an ongoing evaluation by USFDA of the safety of biologics throughout their lifecycle, the infant body burden of mercury following scheduled exposures to thimerosal preservative in inactivated influenza vaccines in the United States was estimated and compared to the infant body burden of mercury following daily exposures to dietary methylmercury at the reference dose established by the USEPA. Body burdens were estimated using kinetic parameters derived from experiments conducted in infant monkeys that were exposed episodically to thimerosal or MeHg at identical doses. We found that the body burden of mercury (AUC) in infants (including low birth weight) over the first 4.5 years of life following yearly exposures to thimerosal was two orders of magnitude lower than that estimated for exposures to the lowest regulatory threshold for MeHg over the same time period. In addition, peak body burdens of mercury following episodic exposures to thimerosal in this worst‐case analysis did not exceed the corresponding safe body burden of mercury from methylmercury at any time, even for low‐birth‐weight infants. Our pharmacokinetic analysis supports the acknowledged safety of thimerosal when used as a preservative at current levels in certain multidose infant vaccines in the United States.     

Reciprocal Family,Friendship and Church Support Networks of African Americans: Findings from the National Survey of American Life

This study examined reciprocal support networks involving extended family, friends and church members among African Americans. Our analysis examined specific patterns of reciprocal support (i.e., received only, gave only, both gave and received, neither gave or received), as well as network characteristics (i.e., contact and subjective closeness) as correlates of reciprocal support. The analysis is based on the African American subsample of the National Survey of American Life. Overall, our findings indicate that African Americans are very involved in reciprocal support networks with their extended family, friends and church members. Respondents were most extensively involved in reciprocal supports with extended family members, followed closely by friends and church networks. Network characteristics (i.e., contact and subjective closeness) were significantly and consistently associated with involvement with reciprocal support exchanges for all three networks. These and other findings are discussed in detail. This study complements previous work on the complementary roles of family, friend and congregational support networks, as well as studies of racial differences in informal support networks.     

A Dynamic Model of Demand for Houses and Neighborhoods

This paper develops a dynamic model of neighborhood choice along with a computationally light multi‐step estimator. The proposed empirical framework captures observed and unobserved preference heterogeneity across households and locations in a flexible way. We estimate the model using a newly assembled data set that matches demographic information from mortgage applications to the universe of housing transactions in the San Francisco Bay Area from 1994 to 2004. The results provide the first estimates of the marginal willingness to pay for several non‐marketed amenities—neighborhood air pollution, violent crime, and racial composition—in a dynamic framework. Comparing these estimates with those from a static version of the model highlights several important biases that arise when dynamic considerations are ignored.     

Optimal Digital Rights Management with Uncertain Piracy

Many firms that sell digital copies of copyrighted materials online face a common dilemma: the use of digital rights management (DRM) to impede pirates can impose restrictions on legitimate use. We introduce a two‐period model in which the use of DRM in the first period affects the probability that a consumer finds a pirated copy in the second period; the threat of legal action reduces consumers’ consumption of pirated copies; and firms choose whether to sell, and at what prices, either strongly or weakly DRM‐protected products, or both. Furthermore, we incorporate the role of uncertainty concerning future levels of piracy. Using a two‐period model with uncertainty, we investigate a firm's optimal DRM strategies and present the optimal pricing strategy as well as product launch strategy under different market conditions. We find that one important characteristic of the optimal strategy is that it is optimal to maintain the same product line configuration strategy for both periods. We also characterize the conditions under which each strategy is optimal.     

The Experience-Earnings Profile: Productivity-Augmenting or Purely Contractual? Evidence from the UK

We test the human capital interpretation of the experience-earnings profile. Does the upward sloping portion of the experience-earnings profile reflect on-the-job training which in turn causes the experience-productivity profile to slope upwards, or do purely contractual factors determine the nature of life-cycle earnings. Herein, we provide additional evidence on the relationship between productivity and earnings by examining earnings differentials in the UK academic labor market for economists. Using a test first suggested by Mincer, we find that the empirical results are consistent with human capital theory. We find that, although the positive relationship between earnings and experience persists when individual productivity measures are included in the salary equations for lecturers and senior lecturers, the positive relationship becomes statistically insignificant when the same productivity measures are included in the salary equations for professors. For lecturers and senior lecturers, the experience-salary profile properly reflects the structure of the national pay scale rather than variations in individual research productivity. At the professor level, where individual salaries are not determined by a pay scale, the data support the human capital explanation of the positive experience-earnings profile.

Translators, traitors, and traducers: Perjuring Hawaiian same-sex texts through deliberate mistranslation

In the long history of the West's encounter with Hawaiian culture, which began in the late 1700s with Captain Cook, translators and translations have often been the tools of intentional falsehood, thus demonstrating the truth of the Italian proverb, Traduttore, traditore ("the translator is a traitor")--particularly with regard to same-sex texts. The standards of truth have often been subverted in translation by the demands of foreign religion, hegemony, business, and academe. This subversion continues to this day in the form of the "missionary mentality" in politics and law. The way out of this situation is a brutally honest cleaning-off of the besmirched Hawaiian texts.     

From "Male Bonding Rituals" to "Suicide Tuesday": A qualitative study of issues faced by gay male ecstasy (MDMA) users

Use of MDMA and other club drugs has increased among gay men, but questions remain concerning the use, context, and popularity of these drugs; and views of their side effects. We interviewed in-depth 12 gay MDMA users in New York. MDMA had specific appeals to gay men, who often described isolation and stigmatization. Users underwent a period of initiation and social networks often became comprised of greater numbers of other users. Club environments fostered drug use and vice versa. Awareness of potential adverse effects varied and was minimized. Appropriate educational and prevention programs are needed to address these issues, and must take into account the specific contexts of these gay men's lives.     

Single-Parenthood and Poverty in Great Britain

ABSTRACT This paper examines empirically the relationship between single-parenthood and absolute poverty in Great Britain. Data from two years of the Family Expenditure Survey are used (1968 and 1986). A poverty measure that is additively decomposable with population share weights, and consistent with Sen's axiomatic approach to poverty measurement, is used to decompose the total amount of poverty into the “shares” accruing to different types of households (i.e. female and male single-parents, two-parent households and “other” types of households). Three main conclusions concerning the poverty experience of British single-parents emerge from the analysis. The first is that poverty rates for single-parent households are generally higher than the average for all households. However, this disadvantage is not as large as one might expect, especially when a comparison is made with two-parent households. The second is that single-parent households are over-represented in the ranks of the poor. That is, their “share” of total poverty is greater than their population share. The third is that increasing single-parenthood has had little impact on the overall trend in absolute poverty in the period 1968 to 1986.