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231.
Robin Pierce J.D. Ph.D. 《Accountability in research》2013,20(4):262-282
Deception in human subject research is neither uncommon nor prohibited. The use of deception in the recruitment phase of clinical research has received relatively little attention. Given that informed consent is foundational to human subject research, the practice of misrepresenting the study purpose in clinical research would seem to contradict one of the fundamental tenets of ethical human subjects research. Using the example of prodromal psychosis, this article the ethical and legal implications of deception in recruitment and the sufficiency of current guidance on the practice when the study involves a stigmatizing condition, the collection of genetic samples, or both. I conclude that when these two elements are present, deception should only be used when absolutely necessary and, if used, researchers should be required to debrief participants before the collection of genetic samples and give particular attention to minimizing risks of privacy breaches. 相似文献
232.
Many studies have examined the effect of life events, education, and income on well-being. Conversely, research concerning well-being as a predictor of life course outcomes is sparse. Diener’s suggestion “to inquire about the effects of well-being on future behavior and success” has, with some exceptions, not yet come to fruition. This article contributes to this body of research. We conceptualize and analyze the interplay between educational achievement, occupational success, and well-being as a complex process. The relationship between these domains is examined drawing on a structure-agency framework derived from Bourdieu and Social Comparison Theory. Social comparison between adolescents and their parents is suggested to be the mechanism explaining the effects of successful and unsuccessful intergenerational transmission of educational achievement and occupational success on well-being. It is further argued that well-being may serve as an individual resource by fostering educational and occupational outcomes. Panel data from the Transition from Education to Employment (TREE) project, a Swiss PISA 2000 follow-up study, was used. The interplay between well-being and successful and unsuccessful intergenerational transfer of educational attainment was analyzed in an autoregressive cross-lagged mixture model framework. Social comparison was found to be related to well-being, while well-being proved to significantly increase the probability of successful intergenerational transfer of educational attainment. 相似文献
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In this article, the Brier score is used to investigate the importance of clustering for the frailty survival model. For this purpose, two versions of the Brier score are constructed, i.e., a “conditional Brier score” and a “marginal Brier score.” Both versions of the Brier score show how the clustering effects and the covariate effects affect the predictive ability of the frailty model separately. Using a Bayesian and a likelihood approach, point estimates and 95% credible/confidence intervals are computed. The estimation properties of both procedures are evaluated in an extensive simulation study for both versions of the Brier score. Further, a validation strategy is developed to calculate an internally validated point estimate and credible/confidence interval. The ensemble of the developments is applied to a dental dataset. 相似文献
235.
W-graph refers to a general class of random graph models that can be seen as a random graph limit. It is characterized by both its graphon function and its motif frequencies. In this paper, relying on an existing variational Bayes algorithm for the stochastic block models (SBMs) along with the corresponding weights for model averaging, we derive an estimate of the graphon function as an average of SBMs with increasing number of blocks. In the same framework, we derive the variational posterior frequency of any motif. A simulation study and an illustration on a social network complete our work. 相似文献
236.
Fatima Affif Chaouche Carrie Rutherford Robin Whitty 《Journal of Combinatorial Optimization》2013,26(2):372-384
Let $(E,{ \mathcal{A}})$ be a set system consisting of a finite collection ${ \mathcal{A}}$ of subsets of a ground set E, and suppose that we have a function ? which maps ${ \mathcal{A}}$ into some set S. Now removing a subset K from E gives a restriction ${ \mathcal{A}}(\bar{K})$ to those sets of ${ \mathcal{A}}$ disjoint from K, and we have a corresponding restriction $\phi|_{\hspace {.02in}{ \mathcal{A}}(\bar{K})}$ of our function ?. If the removal of K does not affect the image set of ?, that is $\mbox {Im}(\phi|_{\hspace {.02in}{ \mathcal{A}}(\bar{X})})=\mbox {Im}(\phi)$ , then we will say that K is a kernel set of ${ \mathcal{A}}$ with respect to ?. Such sets are potentially useful in optimisation problems defined in terms of ?. We will call the set of all subsets of E that are kernel sets with respect to ? a kernel system and denote it by $\mathrm {Ker}_{\phi}({ \mathcal{A}})$ . Motivated by the optimisation theme, we ask which kernel systems are matroids. For instance, if ${ \mathcal{A}}$ is the collection of forests in a graph G with coloured edges and ? counts how many edges of each colour occurs in a forest then $\mathrm {Ker}_{\phi}({ \mathcal{A}})$ is isomorphic to the disjoint sum of the cocycle matroids of the differently coloured subgraphs; on the other hand, if ${ \mathcal{A}}$ is the power set of a set of positive integers, and ? is the function which takes the values 1 and 0 on subsets according to whether they are sum-free or not, then we show that $\mathrm {Ker}_{\phi}({ \mathcal{A}})$ is essentially never a matroid. 相似文献
237.
Carl Senior Robin Martin Geoff Thomas Anna Topakas Michael West Rowena M. Yeats 《The Leadership Quarterly》2012,23(2):281-291
Developmental stability is the degree to which we can withstand environmental or genetic stressors during development. Fluctuating asymmetry (FA), concerns the extent to which the right and left side of the body is asymmetrical and is one way to measure developmental stability. Two studies were carried out that examined both the predictive value of leader FA with leadership behaviors and its role in facilitating group performance. The first study examined the hypothesis that a leader's FA is correlated with scores on the Multifactor Leadership Questionnaire (MLQ). The results revealed individuals with a more asymmetrical morphology scored higher on the transformational, but not transactional, dimensions of leadership behavior. A second study examined the hypothesis that asymmetrical morphology and leadership effectiveness would share a positive relationship. In this study participants who led a business game exercise, revealed a positive relationship between FA and self-reported well-being and task satisfaction. Importantly, there was also a positive correlation between the leader's FA score and group performance. The role that developmental stability may play in leadership effectiveness is discussed in the wider context of evolutionary psychology. 相似文献
238.
Since the 9/11 terrorist attacks, there has been an increase in public discussion regarding U.S. domestic intelligence activities. Domestic intelligence activities focus on gathering information about potential threats from individuals within the United States, and completely rational members of the public can have different opinions about the acceptability of various alternatives depending on one's values toward privacy, civil liberty, and security. Past studies have demonstrated that construction of a multiobjective value model can help clarify public values in controversial risk debates. This research explores a range of domestic intelligence alternatives that vary on multiple objectives, and applies value-focused thinking to develop a multiattribute utility model to evaluate and compare the alternatives. The process demonstrates the feasibility of eliciting model parameters from individuals and provides a method for identifying the locus of possible disagreements among individuals. The development of the model is described first, followed by insights found from participants who provided both value tradeoffs and performance scores for six different domestic intelligence alternatives. The participants were two student groups and a group of police officers. The analysis showed differences among weights for an additive model for different stakeholder groups and differences among the performance scores. In particular, there is a "halo" effect for alternatives, such that its supporters ranked the alternative higher on all attributes compared to respondents who find the alternative unacceptable. This modeling approach and results offer organizations such as the Department of Homeland Security insights into the debate surrounding new policy initiatives, particularly those requiring sensitive value tradeoffs. 相似文献
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240.
In today's increasingly technology‐mediated world, individuals are often confronted with a decision of whether to obtain services through online, self‐service technologies or traditional, nontechnological alternatives. Understanding the mechanisms by which consumers choose among these competing service channels represents an important concern for organizations, consumers, and Web site designers. This study develops a research model based on Social Cognitive Theory to explain and predict service channel preferences that arise in the early stages of adoption, before a consumer conducts business using a particular channel. The model is subsequently tested in the brokerage services context, using observations obtained via survey. Given the growing popularity of online investing combined with the challenging prospect of making optimal decisions in an inherently risky environment, the context offers insights of practical and theoretical importance. The results suggest that task‐specific self‐efficacy beliefs serve as the activating mechanism kicking off a chain of psychological events that entice consumers to favor a particular service channel. Higher levels of self‐efficacy induce individuals to prefer the online approach. In addition to its direct effect on preference for the online service channel, higher levels of self‐efficacy influence one's propensity to take risks and expectations of performance‐oriented rewards, which, in turn, sway consumers to favor the online service channel. Furthermore, self‐efficacy and perceptions concerning the credibility of online information interact to affect service channel preference. Consumers are more likely to prefer the online service channel when they view themselves as capable and perceive online sources to be credible. Implications for theory and practice are discussed in light of the findings. 相似文献