Competing risk methods are time‐to‐event analyses that account for fatal and/or nonfatal events that may potentially alter or prevent a subject from experiencing the primary endpoint. Competing risk methods may provide a more accurate and less biased estimate of the incidence of an outcome but are rarely applied in cardiology trials. APEX investigated the efficacy of extended‐duration betrixaban versus standard‐duration enoxaparin to prevent a composite of symptomatic deep‐vein thrombosis (proximal or distal), nonfatal pulmonary embolism, or venous thromboembolism (VTE)–related death in acute medically ill patients (n = 7513). The aim of the current analysis was to determine the efficacy of betrixaban vs standard‐duration enoxaparin accounting for non‐VTE–related deaths using the Fine and Gray method for competing risks. The proportion of non‐VTE–related death was similar in both the betrixaban (133, 3.6%) and enoxaparin (136, 3.7%) arms, P = .85. Both the traditional Kaplan‐Meier method and the Fine and Gray method accounting for non‐VTE–related death as a competing risk showed equal reduction of VTE events when comparing betrixaban to enoxaparin (HR/SHR = 0.65, 95% 0.42‐0.99, P = 0.046). Due to the similar proportion of non‐VTE–related deaths in both treatment arms and the use of a univariate model, the Fine and Gray method provided identical results to the traditional Cox model. Using the Fine and Gray method in addition to the traditional Cox proportional hazards method can indicate whether the presence of a competing risk, which is dependent of the outcome, altered the risk estimate. 相似文献
The application of the theory of partially ordered sets to voting systems is an important development in the mathematical theory of elections. Many of the results in this area are on the comparative properties between traditional elections with linearly ordered ballots and those with partially ordered ballots. In this paper we present a scoring procedure, called the partial Borda count, that extends the classic Borda count to allow for arbitrary partially ordered preference rankings. We characterize the partial Borda count in the context of weighting procedures and in the context of social choice functions. 相似文献
This article seeks to describe the work of dairy products speculators. It reveals the effort, cognitive and material, that enables these actors to handle the widening of their range of action, but also the contraction in the timescale of that action, two dynamics characteristic of the financialization process currently underway in certain international agricultural markets. In contrast with certain works critical of finance, which report a decoupling of the “financial sphere” from the “real economy”, it reveals – through close attention to the graphic media employed – agents who are aware of the materiality of the products they manipulate, despite their growing distanciation, both cognitive and geographical, from the target of their activity. 相似文献
Scotland has a lower life expectancy than any country in Western Europe or North America, and this disadvantage is concentrated above age 50. According to the Human Mortality Database, life expectancy at age 50 has been lower in Scotland than in any other developed country since 1980. Relative to 15 developed countries that we have chosen for comparison, Scotland's life expectancy in 2009 at age 50 was lower by an average of 2.5?years for women and 1.6?years for men. We estimate that Scottish women lost 3.6?years of life expectancy at age 50 as a result of smoking, compared to 1.4?years for the comparison countries. The equivalent figures among men are 3.1 and 2.1?years. These differences are large enough for the history of heavy smoking in Scotland to account both for most of the shortfall in life expectancy for both sexes and for the country's unusually narrow sex differences in life expectancy. 相似文献
While some research has uncovered racial differences in patterns of pornography viewership, no studies to date have considered how these patterns may be changing over time or how these trends may be moderated by other key predictors of pornography viewership—specifically, gender and religion. Using nationally representative data from the 1973–2016 General Social Survey (GSS; N = 20,620), and taking into account different ethnoreligious histories with pornography as a moral issue, we examined how race, gender, and religion intersect to influence trends in pornography viewership over 43 years. Analyses revealed that Black Americans in general were more likely to view pornography than Whites, and they were increasing in their pornography viewership at a higher rate than Whites. Moreover, Black men were more likely to consume pornography than all other race/gender combinations, but differed only from White women in their increasing rate of pornography viewership. Lastly, frequent worship attendance moderated trends in pornography viewership only for White men. By contrast, regardless of attendance frequency, Black men and women showed increasing rates of pornography use, while White women showed flat rates. We conclude by discussing the implications of these findings for research on the intersections of race, gender, religion, and sexuality. 相似文献
The volunteer experience in organizational context has received far less scrutiny. Studies have indicated specific organizational settings, such as schedule flexibility, orientation and training, empowerment, social interaction, reflection, and rewards, and each has certain influences on their satisfaction and intention of remain. But we do not know their combined impact as organizational facilitators. This study focused on a sample of hospital volunteering, which occupies the largest service hours of volunteering work in Taiwan. We explored the experience of organizational facilitators that affect the satisfaction and loyalty of the volunteers from 868 valid questionnaires in a metropolitan hospital. The results showed that volunteers with more experiences on social interaction, reflections, and rewards, were more satisfied. In term of loyalty, volunteers with higher satisfaction showed higher willing to remain, recommend, accept services, and donate. Furthermore, because of flexible schedules and preferable rewards, the volunteers were more willing to remain; because of more training, higher social interaction, reflections, and rewards, the volunteers were more willing to recommend volunteering and accept services. Additionally, less flexible schedules, better empowerment, and more reflections as well as rewards influenced volunteers to be more motivated to donate. Implications of organizational efforts toward the hospital volunteer management are discussed.
Social Indicators Research - The study examined the effect of urbanization on income inequality for 21 Sub Saharan African countries over the period 1984–2014 using heterogeneous panel... 相似文献
Abstract Objectives: The study determined prevalence of asymptomatic nonurethral gonorrhea and chlamydia in men who have sex with men (MSM) seen at the Columbia University Health Service for routine care. Participants: The study enrolled 200 participants from March 2007 to May 2010. Results: Specimens were tested using culture and nucleic acid amplification testing (NAAT): 3.5% (n = 7) tested positive for pharyngeal gonorrhea by NAAT, none were positive by culture; 3% (n = 6) tested positive for rectal chlamydia by NAAT and 0.5% (n = 1) by culture. Conclusions: The incidence of pharyngeal gonorrhea and rectal chlamydia in MSM who visited the Columbia Health Service was similar to rates of asymptomatic nonurethral gonorrhea and chlamydia in studies conducted in the MSM population in non-university settings. This suggests that, following the Centers for Disease Control and Prevention guidelines, (1) 3-site testing for MSM seen at the Columbia clinic is indicated. NAAT is more sensitive than culture for nonurethral gonorrhea and chlamydia. 相似文献
When a subordinate receives abusive treatment from a supervisor, a natural response is to retaliate against the supervisor. Although retaliation is dysfunctional and should be discouraged, we examine the potential functional role retaliation plays in terms of alleviating the negative consequences of abusive supervision on subordinate justice perceptions. Based on the notion that retaliation following mistreatment can restore justice for victims, we propose a model whereby retaliation following abusive supervision alleviates the negative effect of abusive supervision on subordinate justice perceptions. In two experimental studies (Study 1 and 2), whereby we manipulated abusive supervision and subordinate symbolic retaliation—in particular, harming a voodoo doll that represents the abusive supervisor—we found general support for our predictions. Theoretical and practical implications are discussed. 相似文献