MULTICRITERIA OPTIMIZATION: A GENERAL CHARACTERIZATION OF EFFICIENT SOLUTIONS*

In the context of deterministic multicriteria maximization, a Pareto optimal, nondominated, or efficient solution is a feasible solution for which an increase in value of any one criterion can only be achieved at the expense of a decrease in value of at least one other criterion. Without restrictions of convexity or continuity, it is shown that a solution is efficient if and only if it solves an optimization problem that bounds the various criteria values from below and maximizes a strictly increasing function of these several criteria values. Also included are discussions of previous work concerned with generating or characterizing the set of efficient solutions, and of the interactive approach for resolving multicriteria optimization problems. The final section argues that the paper's main result should not actually be used to generate the set of efficient solutions, relates this result to Simon's theory of satisficing, and then indicates why and how it can be used as the basis for interactive procedures with desirable characteristics.     

EFFECTS OF LEARNING ON RESOURCE ALLOCATION DECISIONS

Learning curves have important implications for managerial planning and control. This paper considers the effect of learning on managerial planning models for productmix problems that can be handled by a linear-programming formulation. An approach to incorporate learning effects in the planning model is proposed in this paper. The feasibility and superiority of the proposed approach over the traditional approach are discussed through the use of a linear-programming problem.     

OPTIMAL SELECTION OF MATCHED PAIRS FROM LARGE DATA BASES

This paper considers the problem of selecting matched pairs of observations for the reduction of bias in statistical hypothesis testing. A Euclidean distance function is suggested for measuring the similarity between paired observations. The matching process is then formulated initially as an assignment problem. Alternative formulations of the problem that would reduce computational difficulty are considered.     

USING DUMMY VARIABLES TO CHECK FOR ROUNDING ERROR IN COMPUTERIZED REGRESSION PROGRAMS*

After a brief review of the role of dummy variables in regression analysis and the current state-of-the art in rounding/truncation error detection in computerized least squares programs, this paper presents a theorem that can be used to detect this type of error whenever an analyst is running a regression program that has one (or more) dummy variables as independent variables.     

Putting Process (Back) In: Research on the Internationalization Process of the Firm

This paper provides a critique of existing research on the internationalization process of the firm and proposes an agenda for future inquiry. In recent years, process approaches have received increasing attention in management research, leading to a more refined understanding of the distinction between process and variance paradigms. We apply a process lens to a well‐established sub‐field of international business, namely the internationalization process of the firm. We review how this research tradition has evolved over four decades. The review commences with a reassessment of the seminal ‘stage models’ that date back to the 1970s. It then proceeds to classify subsequent research on the basis of whether it includes process data and/or process theorizing. It is found that the majority of studies in this review do not combine process data with process theorizing. We show how, even in studies that contain some process elements, a process approach is not always sustained throughout the paper. On the basis of this review, six research themes are proposed, which would form the basis for a process agenda for future research.     

Modeling the Adenoma and Serrated Pathway to Colorectal CAncer (ASCCA)

Several colorectal cancer (CRC) screening models have been developed describing the progression of adenomas to CRC. Currently, there is increasing evidence that serrated lesions can also develop into CRC. It is not clear whether screening tests have the same test characteristics for serrated lesions as for adenomas, but lower sensitivities have been suggested. Models that ignore this type of colorectal lesions may provide overly optimistic predictions of the screen‐induced reduction in CRC incidence. To address this issue, we have developed the Adenoma and Serrated pathway to Colorectal CAncer (ASCCA) model that includes the adenoma‐carcinoma pathway and the serrated pathway to CRC as well as characteristics of colorectal lesions. The model structure and the calibration procedure are described in detail. Calibration resulted in 19 parameter sets for the adenoma‐carcinoma pathway and 13 for the serrated pathway that match the age‐ and sex‐specific adenoma and serrated lesion prevalence in the COlonoscopy versus COlonography Screening (COCOS) trial, Dutch CRC incidence and mortality rates, and a number of other intermediate outcomes concerning characteristics of colorectal lesions. As an example, we simulated outcomes for a biennial fecal immunochemical test screening program and a hypothetical one‐time colonoscopy screening program. Inclusion of the serrated pathway influenced the predicted effectiveness of screening when serrated lesions are associated with lower screening test sensitivity or when they are not removed. To our knowledge, this is the first model that explicitly includes the serrated pathway and characteristics of colorectal lesions. It is suitable for the evaluation of the (cost)effectiveness of potential screening strategies for CRC.     

Recent Mortality Trend Reversal in Russia: Are Regions Following the Same Tempo?

After several decades of negative trends and short-term fluctuations, life expectancy has been increasing in Russia since 2004. Between 2003 and 2014, the length of life rose by 6.6 years among males and by 4.6 years among females. While positive trends in life expectancy are observed in all regions of Russia, these trends are unfolding differently in different regions. First, regions entered the phase of life expectancy growth at different points in time. Second, the age- and cause-specific components of the gains in life expectancy and the number of years added vary noticeably. In this paper, we apply decomposition techniques—specifically, the stepwise replacement algorithm—to examine the age- and cause-specific components of the changes in inter-regional disparities during the current period of health improvement. The absolute inter-regional disparities in length of life, measured by the population-weighted standard deviation, decreased slightly between 2003 and 2014, from 3.3 to 3.2 years for males, and from 2.0 to 1.8 years for females. The decomposition of these small changes by ages and causes of death shows that these shifts were the result of diverse effects of mortality convergence at young and middle ages, and of mortality divergence at older ages. With respect to causes of death, the convergence is mainly attributable to external causes, while the inter-regional divergence of trends is largely determined by cardiovascular diseases. The two major cities, Moscow and Saint Petersburg, are currently pioneering mortality improvements in Russia and are making the largest contributions to the inter-regional divergence.     

An Ecological Model for Quantitative Risk Assessment for Schistosomiasis: The Case of a Patchy Environment in the Coastal Tropical Area of Northeastern Brazil

We developed a stochastic model for quantitative risk assessment for the Schistosoma mansoni (SM) parasite, which causes an endemic disease of public concern. The model provides answers in a useful format for public health decisions, uses data and expert opinion, and can be applied to any landscape where the snail Biomphalaria glabrata is the main intermediate host (South and Central America, the Caribbean, and Africa). It incorporates several realistic and case‐specific features: stage‐structured parasite populations, periodic praziquantel (PZQ) drug treatment for humans, density dependence, extreme events (prolonged rainfall), site‐specific sanitation quality, environmental stochasticity, monthly rainfall variation, uncertainty in parameters, and spatial dynamics. We parameterize the model through a real‐world application in the district of Porto de Galinhas (PG), one of the main touristic destinations in Brazil, where previous studies identified four parasite populations within the metapopulation. The results provide a good approximation of the dynamics of the system and are in agreement with our field observations, i.e., the lack of basic infrastructure (sanitation level and health programs) makes PG a suitable habitat for the persistence and growth of a parasite metapopulation. We quantify the risk of SM metapopulation explosion and quasi‐extinction and the time to metapopulation explosion and quasi‐extinction. We evaluate the sensitivity of the results under varying scenarios of future periodic PZQ treatment (based on the Brazilian Ministry of Health's plan) and sanitation quality. We conclude that the plan might be useful to slow SM metapopulation growth but not to control it. Additional investments in better sanitation are necessary.     

Predictors of Antisocial and Prosocial Behavior in an Adolescent Sports Context

This study examined antisocial and prosocial behavior of N = 439 adolescent athletes between 14 and 17 years of age (67 teams). Multi‐level analyses showed that team membership explained 20 and 13 percent of the variance in antisocial and prosocial behavior in the sports context, respectively. The team effects suggest that aggregating antisocial or prosocial adolescents within teams may partially explain differences in antisocial and prosocial behavior among athletes in the sports context. A trend was found toward a relation between higher levels of moral reasoning within teams, and less antisocial behavior in the sports context. Favorable moral atmosphere was positively associated with more prosocial behavior in the sports context. Finally, supportive coach–athlete relationships were associated with both less antisocial and more prosocial behavior in the sports context.