Proteins' promise--progress and challenges in ovarian cancer proteomics

Ovarian cancer is the leading cause of gynaecological cancer death. The mortality rate of ovarian cancer could be greatly decreased if there were a screening test which was able to detect the disease at an early stage, resulting in an increased probability of cure. The most promising prospect for the early detection of ovarian cancer comes from the rapidly advancing field of clinical proteomics. An increasing number of reports on the potential clinical application of proteomics research for early detection as well as risk assessment and management of ovarian cancer are being published. Although the research is very promising, major technical challenges are still preventing new discoveries in ovarian cancer proteomics from being translated into clinical practice.     

Gay, lesbian, bisexual and transgendered (GLBT) experiences with Earth-spirited faith

Earth-spirited faiths (e.g., Pagan and Wiccan spiritualities) have been described as more affirmative toward gay, lesbian, bisexual, and transgendered (GLBT) members than mainstream Judeo-Christian faiths, but no research has explored Earth-spirited faiths' GLBT-affirming behaviors. This study investigated those behaviors as well as the faith experiences of GLBT Earth-spirited individuals. At time of coming out, participants who were affiliated with mainstream Judeo-Christian faiths reported greater faith conflict than those affiliated with Earth-spirited faiths; however, there were no differences in resolution of the conflict between the two groups, internalized homonegativity, or self-acceptance. In addition, Earth-spirited faiths engaged in many GLBT-affirming behaviors.     

“Everything That We Can Do”: A Content Analysis of the Protective Strategies Used by GLBTQ Parents

Despite increased access to parenting rights through legal marriage and adoption, U.S. gay, lesbian, bisexual, transgender, and queer (GLBTQ) parents continue to experience varying levels of support for their families. This study explored protective strategies, or actions taken to meet one's safety needs when vulnerable, that GLBTQ parents pursue. This study included 454 GLBTQ parents from a national survey. Participants' open-ended responses about protective strategies were extracted from the survey and analyzed using content analysis. Responses were coded into 10 categories capturing strategies GLBTQ parents used to protect their families. While strategies utilizing legal supports were common, the most cited strategies were symbolic strategies, including creating a family name and developing written statements of parent wishes. Exploratory analyses revealed no difference in mean number of strategies used between parents who reported having legal status as a parent through adoption or listing on the birth certificate and those without legal parenting status. These results suggest that GLBTQ parents, regardless of their legal parenting status, take intentional measures to achieve a sense of safety and increase social support. The findings reiterate the importance of both legal and social support of GLBTQ parents.     

The Progression of Sexual Relationships

The authors examine factors associated with the advancement or dissolution of newly formed sexual relationships. Data from the 2006–2010 National Survey of Family Growth (NSFG) was used to examine women and men aged 18–39 (n = 2,774) whose most recent sexual relationship began within the 12 months before their interview. Results indicate that newly formed sexual relationships are often transitory. By 12 months, only 23% of respondents remained in nonresidential sexual relationships, another 27% were cohabiting with that partner, and half had ended their relationships. Sexual relationships formed before age 25 are significantly more likely to break up than to transition into cohabitation. Indicators of social class disadvantage, such as living with a stepparent, expedited cohabitation, whereas measures of advantage, such as having a college‐educated mother, deterred transitions into shared living. Racial differences also emerge: Blacks were less likely than Whites to transition rapidly into shared living.     

Reconfigured Everyday Lives of Children from Divorced-Parent Families in Singapore

With the termination of a marriage, children involved inevitably experience dramatic changes in different facets of their lives. This article makes use of narrative accounts of divorced single parents to investigate how their marital dissolution has impacted and changed their children's lives. Empirical data was collected through semi-structured, in-depth interviews with 25 Singaporean divorced parents. Within the policy and social context of Singapore society, I highlight transformations in three specific aspects of the children's lives: one, the reconfigurations of familial relationships and formation of a new family unit; two, the creation of and adaptation to new family practices and routine; three, the adoption of new social identity following parental divorce. This article hopes to present a more nuanced understanding of the divorce experience by emphasizing both the precarious and productive aspects in the children's lives, contra to the existing divorce literature that typically focuses on the former.     

Women Elite Leaders Doing Respectable Business Femininity: How Privilege is Conferred,Contested and Defended through the Body

This paper offers a theory of respectable business femininity. Respectable business femininity is theorized as a discursive and relational process that explains tensions women elite leaders experience at the nexus of being both One and Other and sometimes privileged, embedded notions of leadership as masculine and wider expectations of acceptable embodied femininity. Such tensions manifest through a disciplining of women leaders’ bodies and appearance by self‐and‐others, as a means of appraising women as credible elite leaders and respectable women. Through a qualitative study we show how, within sites of ambiguity, embodied leadership and subjectivities are both enabled and constrained. Accounts highlight how privilege is fluid and (de)stabilized in that it is conferred, contested and defended through women's bodies and appearance. We advance understandings of contemporary respectable femininity, privilege at work, and body work, and consider practical implications for women leaders and management education.     

Religious Social Identities in the Hybrid Self‐presentations of Sikh Businesspeople

This paper explores the identity work practices of Thai Sikh businesspeople. The paper focuses on two important social identities in participants’ self‐presentations – those derived from religious (Sikh) and western business discourses – and identifies powerful tensions in their hybrid identity work. Conducting discourse analysis on identity work practices within interview settings, the authors explore how participants resolve, accommodate or reject these discursive tensions while attempting stable and coherent hybrid self‐presentations. They identify several different forms of hybridity, including what they term ‘equipollence’, which occurs when two equally powerful, contradictory discourses are incorporated in self‐presentations, producing potentially irresolvable intersections and leading to a lack of coherence. Contributions are made to the literatures on religion and work, hybrid identity work processes and social identities.     

The Tempo of Sexual Activity and Later Relationship Quality

Rapid sexual involvement may have adverse long‐term implications for relationship quality. This study examined the tempo of sexual intimacy and subsequent relationship quality in a sample of married and cohabiting men and women. Data come from the Marital and Relationship Survey, which provides information on nearly 600 low‐ to moderate‐income couples living with minor children. Over one third of respondents became sexually involved within the first month of the relationship. Bivariate results suggested that delaying sexual involvement was associated with higher relationship quality across several dimensions. The multivariate results indicated that the speed of entry into sexual relationships was negatively associated with marital quality, but only among women. The association between relationship tempo and relationship quality was largely driven by cohabitation. Cohabiting may result in poorer quality relationship because rapid sexual involvement early in the romantic relationship is associated with entrance into shared living.     

Correlates of perceived effectiveness of the Safe Schools/Healthy Students Initiative

A three-level growth-curve model was applied to estimate perceived impact growth trajectories, using multi-year data from project and school surveys on outcome and program implementation collected from 59 sites and approximately 1165 participating schools in the Safe Schools and Healthy Students Initiative. Primary interest is to determine whether and how project-level and school-level correlates affect schools’ perceptions of the Initiative's effectiveness over time when the effects of the pre-grant environmental conditions, grant operations, and near-term outcomes are considered. Coordination and service integration, comprehensive programs and activities for early childhood development, and change in school involvement were found to be significant predictors of school-perceived overall impact when the effect of poverty was considered. Partnership functioning, perceived importance of school resources, and school involvement were found to be significant predictors of school-perceived impact on substance use prevention when the effect of poverty was considered.