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Context: As the volume and complexity of research have increased, the amount of time spent on Institutional Review Board (IRB) review has decreased. The complexity of research has expanded, requiring increasingly specialized knowledge to review it. Dilemma: Under the current system, increasing numbers of research studies requiring expertise in ethics, new technologies or diverse study designs place a substantial burden upon local IRBs and often result in substantial variability among their reviews. This lack of uniformity in the review process creates uneven human subjects’ protection thus undermining the intent of the Common Rule. Objectives: To outline a scenario for expert centralized IRB review via implementation of a national virtual IRB review system overseen by the Office for Human Research Protections (OHRP). Conclusions: The complicated ethical issues and science involved in much of current research warrant an expert review panel. Centralized review would enable expert review specific to the research at hand, ensure consistency in human subjects protection, reduce the burden on local IRBs, and may reduce time spent obtaining approval. A centralized virtual system would allow IRB members to remain at their institutions while providing unprecedented expert review through currently available technology, and make information regarding monitoring and adverse event reporting available online in real-time.  相似文献   
223.
In this paper we set out what we consider to be a set of best practices for statisticians in the reporting of pharmaceutical industry‐sponsored clinical trials. We make eight recommendations covering: author responsibilities and recognition; publication timing; conflicts of interest; freedom to act; full author access to data; trial registration and independent review. These recommendations are made in the context of the prominent role played by statisticians in the design, conduct, analysis and reporting of pharmaceutical sponsored trials and the perception of the reporting of these trials in the wider community. Copyright © 2010 John Wiley & Sons, Ltd.  相似文献   
224.
Fathers exist in the lives of women and children involved with child welfare authorities, and yet, they are rarely seen by child welfare. This invisibility exists whether or not fathers are deemed as risks or as assets to their families. Using an analysis of fundamental child welfare policies and practices and relevant literature, the paper examines how 'ghost' fathers are manufactured, and how this phenomenon affects families and professionals in child welfare. An analysis of gender, class, race and culture of child welfare discourses shows how these fathers are seen as deviant, dangerous, irresponsible and irrelevant, and even further, how absence in child welfare is inextricably linked to blaming mothers. In failing to work with fathers, child welfare ignores potential risks and assets for both mothers and children.  相似文献   
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This paper contrasts and compares the institutional framework for fatherhood and father involvement and the survey evidence relating to fathers’ contribution to childcare and domestic work in the two countries. It shows that while men's contribution to such activities appears to be increasing in both France and the UK, change is slow and father involvement does not necessarily seem to correlate directly either with patterns of female labour force participation or with the support offered by the institutional framework. The authors explore the theoretical frameworks most appropriate for explaining their findings and situate them primarily in terms of Pfau-Effinger's theorization of the gender arrangement (1998, 2002, 2004). The authors conclude that while change in father involvement is slow, the introduction of statutory and organizational work–life balance measures which alter the gender order open up opportunities for negotiated change in the division of the labour in the home.  相似文献   
227.
This study used a person‐oriented approach to examine links between adolescents' experiences with parents and peers. Cluster analysis classified 361, White, working‐ and middle‐class youth (mean age=12.16 years) based on mothers' and fathers' reports of parental acceptance and adolescents' reports of perceived peer competence. Three patterns were identified: high mother and father acceptance and high peer competence; low mother and father acceptance and high peer competence; and high mother acceptance, moderate father acceptance, and low peer competence. The groups differed with respect to youth's and parents' individual characteristics, family and peer dynamics, and youth functioning over time. Discussion focuses on the utility of a person‐oriented approach for studying parent–peer linkages in early adolescence and their implications.  相似文献   
228.
The present paper evaluates relevant findings on long- and short-term affective states in subjective well-being and argues for a componential model that combines the two into the more general concept of happiness. Two age parameters, one for long-term and one for short-term affect are added to the simple model to account for age changes in happiness. Measures of long- and short-term affect are presented, as is a paradigm for separating the components. Support for the simple model is provided by an experimental investigation with 64 college students who were exposed to positive and/or negative mood induction. As expected, the induction had substantially greater effect on short- than on long-term affect measures, particularly the negative induction procedure. These findings are consistent with predictions. However, multiple age cohorts will have to be assessed within a longitudinal framework to obtain values for the age parameters.  相似文献   
229.
This article reports the results of an analysis of all racial and ethnic relations articles published in the American Journal of Sociology, the American Sociological Review, Social Forces, and Social Problems, from January 1969 through December 1995. The analysis identifies by journal: 1) major methodological orientation(s); 2) how the concepts of “race,” “ethnicity,” and racial and ethnic relations are operationalized, which is useful for examining tendencies toward, or against, reification; 3) substantive content—that is, what a sociology of racial and ethnic relations is; and 4) primary context—that is, are racial and ethnic relations treated as a substantive subdiscipline in their own right, or are they merely a topic of interest for other subdisciplines such as social psychology? In brief, although some differences exist between the journals, all four journals publish disproportionately racial and ethnic relations research that: 1) is highly quantitative as opposed to theoretical, conceptual, or sociohistorical; 2) reifies U.S. Census definitions of race and ethnicity as opposed to critically evaluating such definitions; 3) social psychologizes racial and ethnic relations, or subsumes such relations under stratification processes; and 4) subsumes the racial and ethnic relations problematic under subdiscipline rubrics other than a sociology of racial and ethnic relations. The conclusion discusses the implications of these findings; for example, by virtue of what they publish, these journals construct a paradigmatic frame that gives precedence to, or legitimizes, some views and excludes, or de-legitimizes others.  相似文献   
230.
SHORT REVIEWS     
Books reviewed in this article: Adele E. Clarke , Disciplining Reproduction: Modernity, American Life Sciences, and “the Problems of Sex” Delia Davin , Internal Migration in Contemporary China Anton Kuijsten, Henk de Gans, and Henk de Feijter (eds.) The Joy of Demography… and Other Disciplines: Essays in Honour of Dirk van de Kaa William Petersen , Malthus: Founder of Modern Demography Eric B. Ross , The Malthus Factor: Population, Poverty and Politics in Capitalist Development Nicholas Van Hear , New Diasporas: The Mass Exodus, Dispersal and Regrouping of Migrant Communities Thomas M. Wilson and Hastings Donnan (eds.) , Border Identities: Nation and State at International Frontiers  相似文献   
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