Development of Dose‐Response Models to Predict the Relationship for Human Toxoplasma gondii Infection Associated with Meat Consumption

Toxoplasma gondii is a protozoan parasite that is responsible for approximately 24% of deaths attributed to foodborne pathogens in the United States. It is thought that a substantial portion of human T. gondii infections is acquired through the consumption of meats. The dose‐response relationship for human exposures to T. gondii‐infected meat is unknown because no human data are available. The goal of this study was to develop and validate dose‐response models based on animal studies, and to compute scaling factors so that animal‐derived models can predict T. gondii infection in humans. Relevant studies in literature were collected and appropriate studies were selected based on animal species, stage, genotype of T. gondii, and route of infection. Data were pooled and fitted to four sigmoidal‐shaped mathematical models, and model parameters were estimated using maximum likelihood estimation. Data from a mouse study were selected to develop the dose‐response relationship. Exponential and beta‐Poisson models, which predicted similar responses, were selected as reasonable dose‐response models based on their simplicity, biological plausibility, and goodness fit. A confidence interval of the parameter was determined by constructing 10,000 bootstrap samples. Scaling factors were computed by matching the predicted infection cases with the epidemiological data. Mouse‐derived models were validated against data for the dose‐infection relationship in rats. A human dose‐response model was developed as P (d) = 1–exp (–0.0015 × 0.005 × d) or P (d) = 1–(1 + d × 0.003 / 582.414)^?1.479. Both models predict the human response after consuming T. gondii‐infected meats, and provide an enhanced risk characterization in a quantitative microbial risk assessment model for this pathogen.     

Child labour and inequality

This paper focuses on the role that inequality plays in shaping political support for child labour regulation policies. We provide a model of the evolution of child labour, fertility and human capital where the heterogeneity between low- and high-skilled workers allows for an endogenous analysis of inequality generated by child labour. Depending on the initial level of inequality, child labour regulation policies can affect the welfare of low- and high-skilled workers in different ways and therefore can have an impact on political support for their introduction. The possible conflicts of interest that may arise between the two groups can help explain the difficulties that many governments have when dealing with the issue of child labour.     

Where The Trans Men and Enbies At?: Cissexism,Sexual Threat,and the Study of Sex Work

In this article, I examine the existing research on transgender sex workers and explore how cissexism and sexism overlap and shape this work. Overall, researchers assume that all trans sex workers are women, and all male sex workers are assumed to be cisgender. Transmasculine and other gender non‐conforming sex workers are absent from studies of sex work. Researchers in public health and criminology dominate the literature and this research is limited because it focuses only on trans women and because it focuses primarily on disease and trauma, and almost exclusively on HIV. The literature I examined treats transgender women as a public health “problem” to be solved, rather than addressing their experiences and needs as workers and as people in our society. I argue that in order to have useful applied and policy implications aimed at harm reduction, researchers must use a sociological lens to document what structural conditions push and pull people of various genders into sex markets in the first place. Finally, I advocate for the use of queer, intersectional, and transnational frameworks in future lines of inquiries as a way to push the sociological and public health literature on sex work forward in a way that will benefit all sex workers, their advocates, and service providers.     

An empirical study of quality management practices in the petroleum industry

The purpose of this paper is to empirically study quality management practices in the petroleum industry in Iran. A reliable and valid survey instrument has been used for data gathering from managers in the petroleum industry in Iran. The instrument has been developed based on the criteria of the Malcolm Baldrige National Quality Award (MBNQA), which consists of 13 dimensions of quality management. Correlation analysis has been used to test for a relationship between the quality management constructs and quality results (internal quality results and/or external quality results). Most of the linkages within the Baldrige criteria were supported, which indicates the universal applicability of the Baldrige Award criteria. The result of the correlation analysis indicates that top management support is the major driver for quality management implementation which is significantly correlated with most of the quality management constructs. Furthermore, the results indicated that employee training and employee involvement are significantly correlated with internal (operational) quality results. Customer orientation and supplier quality are not significantly correlated with external quality results (business performance).     

CITIZEN PARTICIPATION IN NATURAL RESOURCE MANAGEMENT: DOES REPRESENTATIVENESS MATTER?

ABSTRACT

The main focus of this research is on the changing role of citizen participation in natural resource management. Evidence suggests that citizens who participate in the management of natural resources are not representative of stakeholders who are impacted by the decisions being made. In an effort to assess the representativeness of citizen participation, we conducted telephone surveys of “residents” who live in the watershed of Tennessee Valley Authority's (TVA) Norris Reservoir and “participants” in TVA's Norris Public Lands Plan. As hypothesized, we found participants to be older, disproportionately male, more educated, and more affluent, and as having higher levels of political efficacy and trust in government than residents. Exploratory analyses revealed many other significant differences between participants and residents. We conclude by suggesting that increased and representative citizen participation is necessary for the successful implementation of an ecosystem-based approach and to address problems associated with non-point source pollution.