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991.
Purpose: The overall purposes of this article are to report the development of a survey instrument, Scientific Misconduct Questionnaire-Revised (SMQ-R) that elicits the perceptions of research coordinators managing clinical trials about the various aspects of scientific misconduct and to present the psychometric analyses for the SMQ-R.

Methods: A panel of five researchers and research coordinators reviewed the original SMQ (Rankin and Esteeves, 1997 Rankin, M. and Esteves, M. 1997. Perceptions of scientific misconduct in nursing. Nursing Research, 46(5): 270276. [PUBMED][CSA][CROSSREF][Crossref] [Google Scholar]) and suggested an additional 42 items based on the review of the literature and their own experiences in research. The SMQ-Revised (SMQ-R) consists of 68 closed-choice items in six sections and one section with 12 open-ended questions. The SMQ-R was sent to 5302 persons who were members of the Association for Clinical Research Professionals (ACRP) or subscribers to Research Practitioner, published by the Center for Clinical Research Practice (CCRP).

Findings: Internal consistency of subscales was assessed with Cronbach's alpha and ranged from .83 to .84. Confirmatory factor analysis was used to test construct validity of the instrument subscales. The factor structure was assessed with the principal factors method, using the squared multiple correlations as initial communality estimates followed by varimax (orthogonal) or biquartimax (oblique) rotations. Analyses revealed five distinct factors among three subscales. Construct validity for the SMQ-R was also assessed by testing hypothesized relationships using the known groups approach.

Conclusion: The current effort demonstrated the usefulness of the SMQ-R in obtaining information from a national sample of experienced research coordinators about their perceptions of the prevalence of different types of scientific misconduct and of factors that influence the occurrence of misconduct. The psychometric evaluation of the SMQ-R suggests good internal consistency for most subscales and suggests adequate construct validity of the instrument as a whole. The analyses also suggest that further refinement of the instrument for future studies is warranted.  相似文献   
992.
In 1993, the National Institutes of Health (NIH) passed The Revitalization Act (Subtitle B) which mandated that all NIH funded clinical trials have “appropriate representation” of minority and women subjects. Our aim was to evaluate the impact of the mandate by examining the reporting and inclusion of minority and female subjects into NIH K-Award funded clinical trials, addressing the minority predominant diagnoses of diabetes and clinical obesity. Using the CRISP search engine and PUBMED, we selected publications published by the National Institute on Aging (NIA) and National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) K-grant recipients during 1989–2004, associated with all the diabetes and obesity clinical trials. Studies were stratified into three timeline categories (1989–1993, pre-mandate; 1993–1996, post-mandate, and 1997–present, well past mandate) to evaluate trends in the recruiting of minorities and women before, during, and after the passing of the Revitalization Act. Of the 165 papers, only 37% disclosed race, a number that did not improve over time (p = .15), whereas 92% disclosed gender. Clinical trials that focused on females increased across the 3 timeframes (p < .001) for diabetes studies but not obesity studies. Overall, disclosure of race declined over the 3 timeframes whereas individually, the disclosure of African Americans improved.  相似文献   
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Abstract

Oliver Mtukudzi's music is known for both its musicality and because it addresses social and political issues. Mtukudzi uses his music to tackle the political realities of Zimbabwe and issues related to AIDS, gender and street children. The use of riddles and innuendo is common within Shona music and it is these tools that Mtukudzi uses to deal with these issues that are not commonly addressed by many other musicians. This article analyses his lyrics and music to examine these particular issues. Particular attention is paid to music because the embedded subtexts of music help to illuminate the subtexts of the lyrics.  相似文献   
994.
SUMMARY

This study explores the perspectives of service providers and youth advocates on bullying of lesbian, gay, bisexual and transgender (LGBT) youth and intersectionalities in LGBT peer victimization. In depth, semi-structured interviews were conducted with nine key informants (4 male, 4 female, 1 transgender male; 4 gay, 3 lesbian, 2 non-identified; 6 white, 1 South Asian, 2 Middle Eastern) recruited using purposive sampling from diverse education and social service settings. Narrative thematic analysis and a constant comparative method were used to identify themes. Five themes emerged from the data: (1) “transgressing gender norm boundaries”; (2) homophobic sexism vs. sexist homophobia; (3) “you choose sexuality or you choose race”; (4) newcomer youth and citizenship; and (5) “multiple wires together … create the cage.” Findings suggest the importance of an intersectional approach to conceptualizing and addressing LGBT bullying and to uncovering the differential experiences of bullying among LGBT youth. Bullying related to sexual orientation should not be assumed to be the only or primary form of violence shaping the lives of LGBT youth.  相似文献   
995.
SUMMARY

Homophobic bullying has come into new prominence given its alleged connection to several recent acts of school violence. This article traces the historiography of homophobic bullying, both in recent years and with reference to the original era of concern over this problem, Victorian England. As can be seen through novels and autobiographies of school life, Victorians linked bullying and sexuality in several important ways. Their traditional understanding actually supported many acts of bullying as a way to teach boys accepted codes of masculine behavior. In the late- and post-Victorian era, growing scientific investigation into human sexual behavior and increasing openness about homosexuality changed this picture to some extent, leading writers to understand bullying as a product of the bully's repressed same-sex desires. Both these views persist today and provide a stimulating context for present-day investigations of homophobic bullying.  相似文献   
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