A Rank-Sum-Type Test for Paired Data with Multiple Endpoints

Clinical trials and other types of studies often examine the effects of a particular treatment or experimental condition on a number of different response variables. Although the usual approach for analysing such data is to examine each variable separately, this can increase the chance of false positive findings. Bonferroni's inequality or Hotelling's T² statistic can be employed to control the overall type I error rate, but these tests generally lack power for alternatives in which the treatment improves the outcome on most or all of the endpoints. For the comparison of independent groups, O'Brien (1984) developed a rank-sum type test that has greater power than the Bonferroni and T² procedures when one treatment is uniformly better (i.e. for all endpoints) than the other treatment(s). In this paper we adapt the rank-sum test to studies involving paired data and demonstrate that it, too, has power advantages for such alternatives. Simulation results are described, and an example from a study measuring the effects of sleep loss on glucose metabolism is presented to illustrate the methodology.     

The Effects of Perceived Barriers,Role Models,and Acculturation on the Career Self‐Efficacy and Career Consideration of Hispanic Women

This study used path analysis to examine the relationship between perceived barriers, acculturation, and role model influence on the career self‐efficacy and career considerations of a sample of Hispanic women. Two path models were examined. The male‐dominated model accounted for 15% of the variance, and the female‐dominated model accounted for 26% of the variance. No relationship was found between the variables of interest and male‐dominated career self‐efficacy and consideration. However, perceived barriers were related to female‐dominated career consideration and Anglo acculturation significantly contributed to female‐dominated career self‐efficacy. Results are discussed with regard to career practice and research with Hispanic women.     

Transnational social work: using a wraparound model

In this article, we explore the wraparound approach of service delivery as a model for transnational social work. The wraparound model, used primarily within community‐based children's mental health services and child protection initiatives, has been effective when planning services for clients and their families with complicated needs, whose care has to be provided within a multiple provider context. Most social work is delivered nationally or internationally rather than trans‐nationally. In the article we outline how the model could be structured to meet the particular needs of transmigrants, including the involvement of NGOs and INGOs, and identify key obstacles and limitations.     

Statistical inference for olfactometer data

Summary.  Olfactometer experiments are used to determine the effect of odours on the behaviour of organisms such as insects or nematodes, and typically result in data comprising many groups of small overdispersed counts. We develop a non-homogeneous Markov chain model for data from olfactometer experiments with parasitoid wasps and discuss a relation with the Dirichlet–multinomial distribution. We consider the asymptotic relative efficiencies of three different observation schemes and give an analysis of data intended to shed light on the effect of previous experience of odours in the wasps.     

Procedures and tables for the construction and selection of chain sampling plans ChSP-4A(c1 ,c2 )r-Part 5

SUMMARY This paper presents a design procedure for ChSP-4A(c1,c2)r plans based on Kullback-Leibler information and the minimum sum of risks. A table that gives the values of the parameters n and k indexed by the acceptable quality level (AQL) and limiting quality level (LQL) is presented, from which one can select a plan which gives a desired AQL and LQL when the producer's risk alpha= 0.05 and the consumer's risk beta = 0.10. A concluding remark for this series of five papers is given at the end of this paper.     

Vocal determinants of first impressions of young children

Audiotapes of the voices of77 preschool children were prepared. Subjects listened to the tapes, and then provided their impressions of the competence, leadership, dominance, warmth, and honesty of the children. Judgments of the voices' babyishness and attractiveness were also obtained. Perceivers reliably discriminated the children's voices along the dimensions of babyishness and attractiveness. Moreover, analyses revealed that the previously documented impact of these characteristics on first impressions of adults extends to impressions of young children. The similarity of the effects of these characteristics on impressions formed about children to those revealed for adults suggests that vocal qualities may have an impact on personality development via a process of self-fulfilling prophecy.     

Clinical social work and the family court: A new role in child sexual abuse cases

Clinical social workers encounter difficult treatment issues when working with children where there is a suspicion of child sexual abuse, or where there has been an indicated child protective services case but no family court action. This article outlines a new role for the clinical social worker to play in relationship to the family court system. The author argues that the involvement of the clinician in an assessment process developed to aid the court can aid in the protection of children and set the stage for effective intervention and treatment.Director, Center for Training and Research in Child Abuse and Family Violence.     

Measures of Compounding Conservatism in Probabilistic Risk Assessment

Concern about the degree of uncertainty and potential conservatism in deterministic point estimates of risk has prompted researchers to turn increasingly to probabilistic methods for risk assessment. With Monte Carlo simulation techniques, distributions of risk reflecting uncertainty and/or variability are generated as an alternative. In this paper the compounding of conservatism⁽¹⁾ between the level associated with point estimate inputs selected from probability distributions and the level associated with the deterministic value of risk calculated using these inputs is explored. Two measures of compounded conservatism are compared and contrasted. The first measure considered, F , is defined as the ratio of the risk value, R _d, calculated deterministically as a function of n inputs each at the j th percentile of its probability distribution, and the risk value, R _j that falls at the j th percentile of the simulated risk distribution (i.e., F=R_d/R_j). The percentile of the simulated risk distribution which corresponds to the deterministic value, R_d , serves as a second measure of compounded conservatism. Analytical results for simple products of lognormal distributions are presented. In addition, a numerical treatment of several complex cases is presented using five simulation analyses from the literature to illustrate. Overall, there are cases in which conservatism compounds dramatically for deterministic point estimates of risk constructed from upper percentiles of input parameters, as well as those for which the effect is less notable. The analytical and numerical techniques discussed are intended to help analysts explore the factors that influence the magnitude of compounding conservatism in specific cases.     

Mental load and work stress as two types of energy mobilization

A conceptual framework is presented in which mental load and stress are regarded as two distinct biobehavioural states in the work environment that differ in energy mobilization, mood and coping strategy. The framework combines two types of theory that are based on human performance research using laboratory tasks on the one hand and applied research in the work environment on the other. A high workload is regarded as an important but not a critical factor in the development of stress symptoms. Even under unfavourable conditions it is possible to work intensively and to be highly activated without feelings of strain or psychosomatic complaints. In contrast, working conditions that provide few possibilities for control and little social support or are associated with reduced well-being and increased health risks. The two states differ in activation, coping style and mood. A proper distinction is important not only for theory building but also for the reconstruction of the work environment. It may lead to recommendations that aim to enhance the work efficiency of employees while reducing the probability that stress responses will occur.