慢性肺心病患者动脉血气参数与肺性脑病的关系探讨

目的探讨慢性肺心病患者动脉血二氧化碳分压（PCO2）、氧分压（PO2）、酸碱失衡与肺性脑病发生率的关系。方法对我院2005年以来住院的慢性肺心病患者250例进行分析。结果慢性肺心病患者发生肺性脑病并发症与动脉血二氧化碳分压升高、酸中毒、氧分压降低密切相关。结论对慢性肺心病患者动态监测动脉血气有利于早期发现肺性脑病并发症和及时治疗。     

构建和谐社科界的实践探索与思考

社科界的和谐是和谐社会的重要组成部分,也是繁荣发展哲学社会科学的重要条件。因此,努力构建和谐社科界,是社科联当前和今后工作中必须重视和着力解决的重要课题。社科界是社会的有机组成部分,和谐社科界应按照和谐社会的要求来设计。社科联是党和政府联系广大哲学社会科学工作者的桥梁和纽带,在促进整个社科界的和谐中发挥着重要作用,社科界和谐的基础和关键在社科联。     

Leading beyond regulatory approval: Opportunities for statisticians to optimize evidence generation and impact clinical practice

The role and value of statistical contributions in drug development up to the point of health authority approval are well understood. But health authority approval is only a true ‘win’ if the evidence enables access and adoption into clinical practice. In today's complex and evolving healthcare environment, there is additional strategic evidence generation, communication, and decision support that can benefit from statistical contributions. In this article, we describe the history of medical affairs in the context of drug development, the factors driving post-approval evidence generation needs, and the opportunities for statisticians to optimize evidence generation for stakeholders beyond health authorities in order to ensure that new medicines reach appropriate patients.