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991.
Abstract

This article provides findings of a qualitative study exploring the interactions of eight Deaf participants and one hearing ally with the justice system in Northern Ireland, where the Disability Discrimination Act requires solicitors to make ‘reasonable adjustments’ in order to provide effective access to Deaf clients. Three thematic categories emerged: (a) barriers to accessing justice, (b) work Deaf people do for access, and (c) the need to educate solicitors about access. A central strain ran through these themes: the idea that ‘reasonable adjustment’ must reflect the value of sign language interpreters in facilitating effective communication access for all the parties.  相似文献   
992.
Abstract

Individuals on the autism spectrum are at an increased risk of experiencing violence. This study sought to understand the opinions of adults on the spectrum regarding potential risk and protective factors for interpersonal violence. Twenty-two adults (12 men; 18 to 53 years of age) participated in semi-structured qualitative interviews. Interviews were recorded, transcribed, and analysed. The results of the qualitative analysis identified individual and contextual risk and protective factors. Protective themes focused on individual needs (awareness of the self and the environment, interpersonal knowledge/skills, skill building strategies) and supportive contexts (benefits of a trusted person, advocates, fostering acceptance and inclusion). There is a need for strategies to decrease the vulnerability to, and the impact of, interpersonal violence. Individuals on the spectrum have the capacity to provide important information regarding safety promotion and risk factors for interpersonal violence, and their expertise should play a role in guiding efforts that promote safety.  相似文献   
993.
994.
This paper considers estimation and prediction in the Aalen additive hazards model in the case where the covariate vector is high-dimensional such as gene expression measurements. Some form of dimension reduction of the covariate space is needed to obtain useful statistical analyses. We study the partial least squares regression method. It turns out that it is naturally adapted to this setting via the so-called Krylov sequence. The resulting PLS estimator is shown to be consistent provided that the number of terms included is taken to be equal to the number of relevant components in the regression model. A standard PLS algorithm can also be constructed, but it turns out that the resulting predictor can only be related to the original covariates via time-dependent coefficients. The methods are applied to a breast cancer data set with gene expression recordings and to the well known primary biliary cirrhosis clinical data.  相似文献   
995.
In quantitative trait linkage studies using experimental crosses, the conventional normal location-shift model or other parameterizations may be unnecessarily restrictive. We generalize the mapping problem to a genuine nonparametric setup and provide a robust estimation procedure for the situation where the underlying phenotype distributions are completely unspecified. Classical Wilcoxon–Mann–Whitney statistics are employed for point and interval estimation of QTL positions and effects.  相似文献   
996.
Is the Study of Happiness a Worthy Scientific Pursuit?   总被引:1,自引:1,他引:0  
This paper critiques the view that the study of happiness is not a worthy scientific pursuit. The happiness set point and hedonic treadmill theories denote the complexity of increasing happiness levels due to genetic limitations and adaptation, however, there is mounting evidence to suggest that with the use of appropriate measures and specific interventions aimed at fostering strengths and virtues, happiness can be increased. Furthermore, the benefits of investigating methods for increasing happiness include improvements in physical, psychological and social health and well-being. It is concluded that approaching human needs from a top down or holistic standpoint where individuals can use their strengths to overcome life’s challenges, is beneficial to health and well-being. Hence, the study of happiness is a worthy scientific pursuit.  相似文献   
997.
998.
Scientific techniques for inventory management typically are applied to systems containing many items. Such techniques require an estimation of the demand variance (and mean) of each item from historical data. This research demonstrates a significant potential for improvement in system cost performance from using least-squares regression fits of a variance-to-mean functional relation instead of the standard statistical variance estimate. Even when there is a moderate degree of heterogeneity among items and when the form of the variance-to-mean relation is misspecified, substantial cost savings may be realized. The cost of statistical uncertainty may be reduced by half. The research also provides evidence that system cost is fairly insensitive to the number of items used to fit the regression. This paper provides the underlying reason why a regression-derived variance estimator yields lower cost: it is less variable than the usual individual item variance estimator.  相似文献   
999.
In a recent paper, Pinto and Mabert [5] presented a lot-sizing rule and an improvement procedure for the joint lot-sizing problem with zero setup costs. We show that this procedure often yields infeasible schedules. We also present and discuss two interesting properties of the joint lot-sizing problem with zero setup costs. A numerical example to illustrate the second property is provided.  相似文献   
1000.
Few programs to enhance fathers' engagement with children have been systematically evaluated, especially for low‐income minority populations. In this study, 289 couples from primarily low‐income Mexican American and European American families were randomly assigned to one of three conditions and followed for 18 months: 16‐week groups for fathers, 16‐week groups for couples, or a 1‐time informational meeting. Compared with families in the low‐dose comparison condition, intervention families showed positive effects on fathers' engagement with their children, couple relationship quality, and children's problem behaviors. Participants in couples' groups showed more consistent, longer term positive effects than those in fathers‐only groups. Intervention effects were similar across family structures, income levels, and ethnicities. Implications of the results for current family policy debates are discussed.  相似文献   
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