A new class of measurement-error models,with applications to dietary data

Measurement-error modelling occurs when one cannot observe a covariate, but instead has possibly replicated surrogate versions of this covariate measured with error. The vast majority of the literature in measurement-error modelling assumes (typically with good reason) that given the value of the true but unobserved (latent) covariate, the replicated surrogates are unbiased for latent covariate and conditionally independent. In the area of nutritional epidemiology, there is some evidence from biomarker studies that this simple conditional independence model may break down due to two causes: (a) systematic biases depending on a person's body mass index, and (b) an additional random component of bias, so that the error structure is the same as a one-way random-effects model. We investigate this problem in the context of (1) estimating distribution of usual nutrient intake, (2) estimating the correlation between a nutrient instrument and usual nutrient intake, and (3) estimating the true relative risk from an estimated relative risk using the error-prone covariate. While systematic bias due to body mass index appears to have little effect, the additional random effect in the variance structure is shown to have a potentially important effect on overall results, both on corrections for relative risk estimates and in estimating the distribution of usual nutrient intake. However, the effect of dietary measurement error on both factors is shown via examples to depend strongly on the data set being used. Indeed, one of our data sets suggests that dietary measurement error may be masking a strong risk of fat on breast cancer, while for a second data set this masking is not so clear. Until further understanding of dietary measurement is available, measurement-error corrections must be done on a study-specific basis, sensitivity analyses should be conducted, and even then results of nutritional epidemiology studies relating diet to disease risk should be interpreted cautiously.     

Forecasting electricity consumption with extra-model information provided by consumers

SUMMARY Univariate time series models make efficient use of available historical records of electricity consumption for short-term forecasting. However, the information (expectations) provided by electricity consumers in an energy-saving survey, even though qualitative, was considered to be particularly important, because the consumers' perception of the future may take into account the changing economic conditions. Our approach to forecasting electricity consumption combines historical data with expectations of the consumers in an optimal manner, using the technique of restricted forecasts. The same technique can be applied in some other forecasting situations in which additional information-besides the historical record of a variable-is available in the form of expectations.     

Safety Stock,Excess Capacity or Diversification: Trade‐Offs under Supply and Demand Uncertainty

Firms mitigate uncertainty in demand and supply by carrying safety stock, planning for excess capacity and diversifying supply sources. In this study, we provide a framework to jointly optimize these three levers in a periodic review infinite horizon setting, and in particular we examine how one can reduce inventory and capacity investments through proper diversification strategies. Observing that a modified base‐stock inventory policy is optimal, we find that the capacity‐diversification problem is well behaved and characterize the optimal mix of safety stock, excess capacity and extra number of supply sources. We find that higher supply uncertainty results in higher safety stock, more excess capacity, and higher diversification. But safety stock and diversification are non‐monotonic in demand uncertainty. Our results can be extended to situations in which suppliers are heterogeneous, and can be used to develop effective heuristics.     

Bayesian estimation and case influence diagnostics for the zero-inflated negative binomial regression model

In recent years, there has been considerable interest in regression models based on zero-inflated distributions. These models are commonly encountered in many disciplines, such as medicine, public health, and environmental sciences, among others. The zero-inflated Poisson (ZIP) model has been typically considered for these types of problems. However, the ZIP model can fail if the non-zero counts are overdispersed in relation to the Poisson distribution, hence the zero-inflated negative binomial (ZINB) model may be more appropriate. In this paper, we present a Bayesian approach for fitting the ZINB regression model. This model considers that an observed zero may come from a point mass distribution at zero or from the negative binomial model. The likelihood function is utilized to compute not only some Bayesian model selection measures, but also to develop Bayesian case-deletion influence diagnostics based on q-divergence measures. The approach can be easily implemented using standard Bayesian software, such as WinBUGS. The performance of the proposed method is evaluated with a simulation study. Further, a real data set is analyzed, where we show that ZINB regression models seems to fit the data better than the Poisson counterpart.     

Determinants of voluntary executive stock option disclosure in Brazil

This study investigates whether the governance attributes of Brazilian companies are associated with voluntary executive stock option (ESO) disclosure. Results show that Brazilian companies voluntarily disclose very little about their ESO plans, and that board size, presence of a compensation committee, and auditing by a Big 4 firm are significantly related to the degree of voluntary ESO disclosure. We also show that family-controlled companies in Brazil are associated with low voluntary ESO disclosure. Results are robust to a number of specification tests, dependent and explanatory variable measurements, and sample composition. This study has professional and regulatory implications for Brazil and other emerging capital markets. The results underscore the need for stricter rules for executive compensation reporting in Brazil, and they invite policy makers and regulators in emerging markets to consider the effects of company-level governance factors on disclosure incentives.     

Smoothing a Time Series by Segments of the Data Range

We consider the problem of estimating a trend with different amounts of smoothness for segments of a time series subjected to different variability regimes. We propose using an unobserved components model to consider the existence of at least two data segments. We first fix some desired percentages of smoothness for the trend segments and deduce the corresponding smoothing parameters involved. Once the size of each segment is chosen, the smoothing formulas here derived produce trend estimates for all segments with the desired smoothness as well as their corresponding estimated variances. Empirical examples from demography and economics illustrate our proposal.     

Commercial sex between men: A prospective diary‐based study

This paper describes the results of a self‐reporting dairy completed by 186 male sex workers (MSWs) over a 2‐week period in Brisbane, Sydney, and Melbourne, Australia. The diary was completed following each commercial sex encounter by the MSW. The results reveal that MSWs reported 2088 commercial sex encounters during the study period, with an average of 11.2 encounters per MSW. The majority of sex encounters took place in either the client's or the MSW's residence, with significant variations by city. The average sexual encounter lasted 70 minutes, and comprised two sexual acts, masturbation and oral sex. Condom use was reported in 67.4% of all the encounters. Using the AIDS Council safe‐sex classification system, the majority of the commercial sex encounters fell in the “safer sex” category; however, there were significant differences by source of clients and place of the encounter. Use of drugs and alcohol reveal interesting patterns: Clients were more likely to use alcohol, while MSWs had significant differences of usage of the different drugs. This study demonstrates that the majority of MSWs are offering and practicing safe sex behaviours, however, MSWs working in the street setting are still likely to be practising unsafe sex. Male sex work is becoming an organised business and this provides opportunities to implement further public health interventions.     

A class of semiparametric transormation frailty models with application to estimating treatment effects and heterogenity in aids clinical traials

Muitivariate failure time data are common in medical research; com¬monly used statistical models for such correlated failure-time data include frailty and marginal models. Both types of models most often assume pro¬portional hazards (Cox, 1972); but the Cox model may not fit the data well This article presents a class of linear transformation frailty models that in¬cludes, as a special case, the proportional hazards model with frailty. We then propose approximate procedures to derive the best linear unbiased es¬timates and predictors of the regression parameters and frailties. We apply the proposed methods to analyze results of a clinical trial of different dose levels of didansine (ddl) among HIV-infected patients who were intolerant of zidovudine (ZDV). These methods yield estimates of treatment effects and of frailties corresponding to patient groups defined by clinical history prior to entry into the trial.     

Development and Consideration of Global Policies for Managing the Future Risks of Poliovirus Outbreaks: Insights and Lessons Learned Through Modeling

The success of the Global Polio Eradication Initiative promises to bring large benefits, including sustained improvements in quality of life (i.e., cases of paralytic disease and deaths avoided) and costs saved from cessation of vaccination. Obtaining and maintaining these benefits requires that policymakers manage the transition from the current massive use of oral poliovirus vaccine (OPV) to a world without OPV and free of the risks of potential future reintroductions of live polioviruses. This article describes the analytical journey that began in 2001 with a retrospective case study on polio risk management and led to development of dynamic integrated risk, economic, and decision analysis tools to inform global policies for managing the risks of polio. This analytical journey has provided several key insights and lessons learned that will be useful to future analysts involved in similar complex decision-making processes.     

The allocation of time to social and leisure activities as social indicators for the integration of aged ethnic minorities

One way in which a better understanding of social indicators to be employed in assessing the degree of social integration of aged ethnic minorities is to determine their time-use patterns for various daily activities. This paper reports on a research project undertaken in a planned community of La Villeneuve, France, which examines (a) the social context in which various activities took place, and (b) the duration and frequency of the activities. This was achieved through the combined techniques of time-budget analysis, social network mapping, and participant observations. Our data provides another dimension appropriate for social indicators research.