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421.
The psychiatric impact of interpersonal abuse associated with an atypical presentation of gender was examined across the life course of 571 male-to-female (MTF) transgender persons from the New York City Metropolitan Area. Gender-related abuse (psychological and physical), suicidality, and Diagnostic and Statistical Manual of Mental Disorders (4th ed., text revision) major depression were retrospectively measured across five stages of the life course using the Life Chart Interview. Among younger respondents (current age of 19–39), the impact of both types of abuse on major depression was extremely strong during adolescence and then markedly declined during later stages of life. Among older respondents (current age of 40–59), the impact of both types of abuse on major depression was strong during adolescence and then marginally declined during later stages of life. The effects of both types of abuse on suicidality were weaker but more consistently observed across the life course among both the younger and older respondents. Gender-related abuse is a major mental health problem among MTF transgender persons, particularly during adolescence. As these individuals mature, however, the consequences of this abuse appear less severe, which may represent the development of moderately effective mechanisms for coping with this abuse.  相似文献   
422.
The findings and recommendations of researchers and specialists in thinking-skill learning and teaching have important implications for classroom efforts to improve student thinking. This summary identifies various types of thinking skills and skill components recommended for classroom instruction. The author describes and cites research-derived features of effective, direct instruction in thinking skills and describes a framework for this instruction. He also describes researcherand specialist-recommended teaching techniques and lesson strategies for introducing any thinking skill, guiding continuing skill practice, and teaching students to transfer thinking skills to other contexts. He presents researcher recommendations of when, where, and why such direct skill instruction can be effectively provided. The research cited here suggests both students' academic achievement and their quality of thinking can be improved by using these techniques and strategies to teach thinking skills in subject-matter courses.  相似文献   
423.
A review of the content of The Career Development Quarterly (CDQ) was conducted for the period between 1994 and 2003. In total, 297 articles were published in CDQ during this period. The content analysis was based on content, authorship, and institutional affiliation. The principal areas of research were career development: life‐span perspectives and women's workforce participation. Of the articles published during this period, 33% fell into 1 of these 2 categories. Compared with the previous analysis (W. Buboltz & M. Savickas, 1994), a change was noted in the amount of research in women's workforce participation, which rose from 1.4% to 12.8%, whereas research on career development interventions fell by approximately 50%. The authors discuss implications and areas for future research.  相似文献   
424.
We present step-wise test procedures based on the Bonferroni-Holm principle for multi-way ANOVA-type models. It is shown for two plausible modifications that the multiple level α is preserved. These theoretical results are supplemented by a simulation study, in a two-way ANOVA setting, to compare the multiple procedures with respect to their simultaneous power and the relative frequency of correctly rejected false hypotheses. Financial support of the Deutsche Forschungsgemeinschaft is gratefully acknowledged.  相似文献   
425.
The authors contend that what can legitimately be owned in a free society is only rights to physical property, not to the value thereof. You are thus free to undermine the value of our property by underselling us, by inventing a new substitute for our property, etc. But you cannot legitimately physically agress against our property, even if its value remains constant despite your efforts. This revised version was published online in July 2006 with corrections to the Cover Date.  相似文献   
426.
427.
The goal of the World Health Organization is to stop routine use of oral poliovirus vaccine shortly after interruption of wild poliovirus transmission. A key component of this goal is to minimize the risk of reintroduction by destruction of polioviruses except in an absolute minimum number of facilities that serve essential functions and implement effective containment. Effective containment begins with a complete facility risk assessment. This article focuses on characterizing the risks of exposure to polioviruses from the essential vaccine production, quality control, and international reference and research facilities that remain. We consider the potential exposure pathways that might lead to a poliovirus reintroduction, including para-occupational exposures and releases to the environment, and review the literature to provide available estimates and a qualitative assessment of containment risks. Minimizing the risk of poliovirus transmission from a poliovirus facility to increasingly susceptible communities is a crucial and ongoing effort requiring understanding and actively managing the potential exposure pathways.  相似文献   
428.
This paper characterizes welfarist social evaluation in a multi-profile setting where, in addition to multiple utility profiles, there may be more than one profile of non-welfare information. We prove a new version of the welfarism theorem in this alternative framework, and we demonstrate that adding a plausible and weak anonymity property to the welfarism axioms generates welfarist social-evaluation orderings that are anonymous.This is a revised version of our earlier paper “Welfarism with multiple non-welfare profiles.” We thank François Maniquet, Kotaro Suzumura, John Weymark, an editor and two referees for comments and discussions. The paper was presented at the International Symposium on Intergenerational Equity in Tokyo, December 2001 and at the Meeting of the Society for Social Choice and Welfare in Pasadena, July 2002. Financial support through a grant from the Social Sciences and Humanities Research Council of Canada is gratefully acknowledged.  相似文献   
429.
Clinical trials in severely diseased populations often suffer from a high dropout rate that is related to the investigated target morbidity. These dropouts can bias estimates and treatment comparisons, particularly in the event of an imbalance. Methods to describe such selective dropout are presented that use the time in study distribution to generate so‐called population evolution charts. These charts show the development of a distribution of a covariate or the target morbidity measure as it changes as a result of the dropout process during the follow‐up time. The selectiveness of the dropout process with respect to a variable can be inferred from the change in its distribution. Different types of selective dropout are described with real data from several studies in metastatic bone disease, where marked effects can be seen. A general strategy to cope with selective dropout seems to be the inclusion of dropout events into the endpoint. Within a time‐to‐event analysis framework this simple approach can lead to valid conclusions and still retains conservative elements. Morbidity measures that are based on (recurrent) event counts react differently in the presence of selective dropout. They differ mainly in the way dropout is included. One simple measure achieves good performance under selective dropout by introducing a non‐specific penalty for premature study termination. The use of a prespecified scoring system to assign a weight for each works well. This simple and transparent approach performs well even in the presence of unbalanced selective dropout. Copyright © 2002 John Wiley & Sons, Ltd.  相似文献   
430.
This paper examines principles for social evaluation under uncertainty in environments with a variable population. In contrast to most of the literature, we employ a model that is formulated in terms of prospects rather than lotteries. Starting from a fixed-population result, a multi-profile variant of Harsanyi’s social aggregation theorem is extended to a variable-population environment. Two nested classes of population principles under uncertainty are characterized. Each is a variable-population extension of ex-ante utilitarianism. The results continue to apply if the probability distribution may vary, as long as probabilities are objectively known or agreed upon by all individuals and society.  相似文献   
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