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101.
102.

Objective

To perform a pilot project to determine if this research design was appropriate to explore potential causal relationships between oral probiotic use and vaginal Group B Streptococcal (GBS) colonisation rates in pregnant women.

Method

Thirty-four GBS-positive women at 36 weeks pregnant were recruited. The participants were randomly allocated to the control group, who received standard antenatal care, or to the intervention group, who received standard antenatal care and a daily oral dose of probiotics for three weeks or until they gave birth. A vaginal GBS swab was collected three weeks post consent or during labour.

Findings

No significant difference was found in vaginal GBS rates between the control and intervention groups. Only seven of 21 women in the intervention group completed the entire 21 days of probiotics. A subgroup analysis, including only those who had completed 14 days or more of probiotics (n = 16), also showed no significant difference in vaginal GBS when compared to the control. The findings did show significantly more vaginal commensals in the probiotics group (p = 0.048).

Discussion

Five possible reasons for the lack of significant results are: the length of the intervention was too short; the dosage of the probiotics was too low; the wrong strains of probiotics were used; the sample size was inadequate; or oral probiotics are ineffective in impacting vaginal GBS.

Implications

The finding of a significant increase of vaginal commensals in women who completed 14 days or more of probiotics supports the potential of probiotics to impact vaginal GBS in pregnancy.  相似文献   
103.

Background

Maternal diets are not consistent with dietary guidance and this may affect the health of mothers and their infants. Nutrition knowledge and motivation may be important factors.

Aims

To assess pregnant women's diets in relation to consistency with the Australian Guidelines for Healthy Eating (AGHE); factors influencing women's adherence to the recommendations; and women's attitudes towards pregnancy-specific nutrition information.

Methods

A cross-sectional study using convenience sampling was undertaken at five hospitals in New South Wales (Australia) and through an online link (October 2012 to July 2013). N = 388 pregnant women completed the survey. Categorical data were analysed using Chi square and logistic regression with significance set at P < 0.05.

Findings

Most participants were highly motivated to adopt a healthy diet, believed they were trying to do so and that knowing about nutrition in pregnancy was highly important. Reported dietary intakes were poor. No pregnant women met the recommended intakes for all five food groups. Poor knowledge of these recommendations was evident. Knowledge of selected recommendations (for Fruit, Vegetables, and Breads and Cereals) increased the likelihood of those foods’ consumption 8 (95% confidence interval [CI], 2.3–27.7), 9.1 (95% CI, 2.6–31.3) and 6.8 (95% CI, 3.4–13.7) times respectively.

Conclusion

Pregnant women had high levels of motivation and confidence in their ability to achieve a healthy diet and understand dietary recommendations, but actually demonstrated poor knowledge and poor adherence to guidelines. Mistaken or false beliefs may be a barrier to effective nutrition education strategies.  相似文献   
104.
The present study tests models derived from four theoretical perspectives: Modernization/free trade theory, gender inequality theory, developmental state theory, and dependency theory. It is based on a sample of 82 less developed countries for the period from 1965 to 1991. We find some support for each theoretical perspective. Foreign trade, investment, and debt dependency have adverse effects on infant mortality, mediated by variables linked to modernization/free trade theory and gender inequality theory. State strength has a beneficial direct effect on infant mortality decline. Women's education and reproductive autonomy have significant direct effects, but also play important roles as mediating variables as does rate of economic growth.  相似文献   
105.
On the morning of April 24, 2013, Rana Plaza, an eight-story building housing five garment factories collapsed killing 1,129 workers and injuring 2,500. It quickly emerged that U.S.- and European-based retailers were sourcing items produced at Rana Plaza. This paper takes the Rana Plaza collapse as a case study of how media discourse constructs ideas about corporate deviance, responsibility, and risk management in the global supply chain. Guided by the crime news frame and global risk governance, newspaper articles from the U.S. and Bangladesh are used for a content analysis. This paper expands the literature of corporate crime and global risk governance to include the fast fashion industry. We find little evidence that either country discusses Rana Plaza as corporate deviance or the criminal condemnation of corporations. We find evidence that global risk governance is nationalized, as U.S. papers shift blame away from U.S. corporations and onto Bangladesh.  相似文献   
106.
Abstract

Analysis of right-censored data is problematic due to infinite maximum likelihood estimates (MLE) and potentially biased estimates, especially for small numbers of events. Analyzing current-status data is especially troublesome because of the extreme loss of precision due to large failure intervals. We extend Firth’s method for regular parametric problems to current-status modeling with the Weibull distribution. Firth advocated a bias reduction method for MLE by systematically correcting the score equation. An advantage is that it is still applicable when the MLE does not exist. We present simulation studies and two illustrative analyses involving RFM mice lung tumor data.  相似文献   
107.
Emotion??s twin roles?C??unite and divide?? our daily life, thus motivating the good and the worst in human behaviour. The way one ??feels?? does influence the way one ??acts?? toward others. If this reasoning is correct, then behaviour can never be without motive or ??motiveless.?? Given the importance of emotions in human communication and decision making, the context of intergroup relations, with its themes of prejudice, stereotyping and discrimination against culturally dissimilar was touched on selectively. Using the Differential Emotions Scale and building upon Boyle??s (Personality 56:747?C750, 1984) work, with students, the present study reports a repeated-measure multiple discriminant function analysis for items across raters. The findings further indicate that most of the DES items are sensitive indicators. The correspondence of some of the results with prior research findings makes facial emotions less the holy grail of the social behaviour field. Likely consequences of emotions are considered, and research needs are discussed vis-a-vis uplifting individual happiness, collective identity and sense of connection to others. Perhaps its implications can be extended to the literature, thus revealing how the different lenses through which human emotions are usually viewed are connected by the incipient/concept attitude and self-identification/labelling that run through each of them.  相似文献   
108.
109.
This paper examines how empirical study of children's involvement in non‐therapeutic health research can contribute to our understanding of the significance of the research to the children themselves. This raises issues that are pertinent to, and which will guide policy relating to ethical protection in research. The paper begins with a brief review of the literature considering how children perceive research in general, and non‐therapeutic health research in particular. The empirical study is then described, outlining the approach to sampling, recruitment and the focus group method used. This is followed by consideration of several key issues relating to research with children, with particular reference to ethical protection. Copyright © 2002 John Wiley & Sons, Ltd.  相似文献   
110.
Summary. In the psychosocial and medical sciences, some studies are designed to assess the agreement between different raters and/or different instruments. Often the same sample will be used to compare the agreement between two or more assessment methods for simplicity and to take advantage of the positive correlation of the ratings. Although sample size calculations have become an important element in the design of research projects, such methods for agreement studies are scarce. We adapt the generalized estimating equations approach for modelling dependent κ -statistics to estimate the sample size that is required for dependent agreement studies. We calculate the power based on a Wald test for the equality of two dependent κ -statistics. The Wald test statistic has a non-central χ 2-distribution with non-centrality parameter that can be estimated with minimal assumptions. The method proposed is useful for agreement studies with two raters and two instruments, and is easily extendable to multiple raters and multiple instruments. Furthermore, the method proposed allows for rater bias. Power calculations for binary ratings under various scenarios are presented. Analyses of two biomedical studies are used for illustration.  相似文献   
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