Consider the standard treatment-control model with a time-to-event endpoint. We propose a novel interpretable test statistic from a quantile function point of view. The large sample consistency of our estimator is proven for fixed bandwidth values theoretically and validated empirically. A Monte Carlo simulation study also shows that given small sample sizes, utilization of a tuning parameter through the application of a smooth quantile function estimator shows an improvement in efficiency in terms of the MSE when compared to direct application of classic Kaplan–Meier survival function estimator. The procedure is finally illustrated via an application to epithelial ovarian cancer data. 相似文献
Background: The majority of people with dementia are cared for by their families at home. This study aimed to elicit family carers' perceptions on home environmental aspects and strategies with the view to identify barriers and facilitators when caring for a person with dementia at home.
Design and methods: Thirteen co-resident family carers were engaged in semi-structured in-depth walking interviews. Interviews were recorded, transcribed and analysed using thematic analysis.
Results: Home environments can pose a number of challenges and opportunities. Aspects of the architectural and interior environment (e.g. size, condition, layout and accessibility, familiarity) are perceived as important (Theme 1) as well as a plethora of environmental strategies that encourage independence and comfort at home (Theme 2). Carers' scepticism, timing, costs, property characteristics and mistrust to services are some barriers to implementing environmental strategies (Theme 3).
Conclusions: Carers improvised solutions via trial and error and need further education on strategies to create an enabling and comfortable home environment. 相似文献
The violent attack on the staff of Charlie Hebdo and an earlier plot to kill cartoonists from the Danish newspaper Jyllands-Posten raise the issue of censorship of satirical religious cartoons to avoid potential retaliatory violence from those offended by the cartoons. With third-person effect (TPE) as the theoretical underpinning, this study examined the relationship among TPE, religiosity, and support for censorship of religious satirical cartoons. Data were collected in May 2015. A national sample of participants (N=374) was acquired through Amazon’s Mechanical Turk. The results show that individuals with a higher degree of religiosity are more likely to support censorship of satirical religious cartoons, and though TPE is not positively correlated to support for censorship, respondents’ perception of the effect of the cartoons on themselves may indicate an increased propensity for supporting censorship. 相似文献
Real-world fall events objectively measured by body-worn sensors can improve the understanding of fall events in older people. However, these events are rare and hence challenging to capture. Therefore, the FARSEEING (FAll Repository for the design of Smart and sElf-adaptive Environments prolonging Independent livinG) consortium and associated partners started to build up a meta-database of real-world falls.
Results
Between January 2012 and December 2015 more than 300 real-world fall events have been recorded. This is currently the largest collection of real-world fall data recorded with inertial sensors. A signal processing and fall verification procedure has been developed and applied to the data. Since the end of 2015, 208 verified real-world fall events are available for analyses. The fall events have been recorded within several studies, with different methods, and in different populations. All sensor signals include at least accelerometer measurements and 58 % additionally include gyroscope and magnetometer measurements. The collection of data is ongoing and open to further partners contributing with fall signals. The FARSEEING consortium also aims to share the collected real-world falls data with other researchers on request.
Conclusions
The FARSEEING meta-database will help to improve the understanding of falls and enable new approaches in fall risk assessment, fall prevention, and fall detection in both aging and disease.
This article critically explores the working lives and views of disabled senior staff working in UK organisations. The qualitative research at the core of the article establishes that some disabled people are confounding established notions of disabled people only working in peripheral employment roles by exploring the working lives and perceptions of disabled managers. The findings do, however, point to continued barriers to what disabled staff in senior positions can be seen to do and be organisationally. Here both practical and ontological risk inheres in organisationally induced change, openness about impairment and risky identities. Such ideas, it is argued, present limits to further promotion and workplace inclusion for some disabled managers. 相似文献
Compromise and toleration as the positive results of human political knowledge and practice,are gradually confirmed and integrated into the realities of the social-political life,becoming the inherent requirements,measuring standards and explicit charaterizations of modern political civilization.Compromise and toleration commonly confirm and promote the progress and upgrade of human political civilization from different angles and levels. 相似文献
Story stem measures are an increasingly popular method for assessing the attachment representations of young children, but little is known of their cross‐cultural applicability. This study aimed to characterise the attachment representations in 73 five‐ to eight‐year‐old children in urban Ghana, West Africa, using the Manchester Child Attachment Story Task (MCAST) to test its feasibility, psychometric characteristics and concurrent associations with caregiver‐ and teacher‐rated child behaviour, and to conduct a qualitative thematic analysis of methodological observations. Among the classifiable cases (92 percent), all attachment classifications were observed, yielding a higher rate of secure attachment than in European samples. Inter‐rater reliability, internal consistency, and internal structure were reasonable and largely similar to European studies, although one structural difference was the separation of ‘child assuagement of distress’ from other secure‐related items. MCAST narratives were associated with teacher‐ and caregiver‐rated hyperactivity, but internal consistency was low in most Strengths and Difficulties Questionnaire scales. Possible culturally‐sensitive explanations for our psychometric and qualitative findings are discussed. Overall, story stems are a promising tool for accessing attachment representations in non‐Western samples, although modifications are likely to improve cross‐cultural equivalence when applied to non‐Western cultures. Further investigation is needed to link MCAST outcomes to parenting and socio‐emotional development. 相似文献