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701.
In this article, we propose that psychological goal functions, such as mental health, as well as income are important elements of social welfare. We examine the relationship between income, depression, social welfare (food stamps and Medicaid) and intimate partner violence, using a person-orientation in a sample from the United States. Data from four time points of a longitudinal study of intimate partner violence are analysed. Clusters of women are derived based on whether or not they received or did not receive food stamps and Medicaid at each of the four time periods. These clusters differ on income and intimate partner violence as well as the trajectory of depression. However, a series of linear models suggests that only intimate partner violence (not income and social welfare variables) predict the development and level of depression over time. The effects of the social welfare variables we examined seem to be domain specific and do not influence the mental health of women receiving these services. 相似文献
702.
Development of a rating form to evaluate grant applications to the Hogg Foundation for Mental Health
Reliance on subjective grant proposal review methods leads private philanthropies to underfund mental health programs, even when foundations have mental health focuses. This article describes a private mental health foundation's efforts to increase the objectivity of its proposal review process by developing a reliable, valid proposal rating form. Staff from the Hogg Foundation for Mental Health, an administrative unit of The University of Texas at Austin, developed the items for the grant proposal rating form (GPRF). Four interns, who had educational backgrounds equivalent to the foundation's grant-making staff, used the GPRF to independently rate 20 grant proposals previously reviewed by the foundation. Internal consistency and interrater reliability were very good. It had good face and construct validity and moderate criterion validity. The GPRF's psychometric properties are sufficient to recommend its use in the foundation's review process and suggest private philanthropies' grant proposal review processes can be made more objective and reliable without compromising validity. 相似文献
703.
704.
Drug discovery is the process of identifying compounds which have potentially meaningful biological activity. A major challenge that arises is that the number of compounds to search over can be quite large, sometimes numbering in the millions, making experimental testing intractable. For this reason computational methods are employed to filter out those compounds which do not exhibit strong biological activity. This filtering step, also called virtual screening reduces the search space, allowing for the remaining compounds to be experimentally tested.In this paper we propose several novel approaches to the problem of virtual screening based on Canonical Correlation Analysis (CCA) and on a kernel-based extension. Spectral learning ideas motivate our proposed new method called Indefinite Kernel CCA (IKCCA). We show the strong performance of this approach both for a toy problem as well as using real world data with dramatic improvements in predictive accuracy of virtual screening over an existing methodology. 相似文献
705.
Jenny Devenport Alexander Schacht The Launch & Lifecycle Special Interest Group within PSI 《Pharmaceutical statistics》2023,22(6):1135-1140
The role and value of statistical contributions in drug development up to the point of health authority approval are well understood. But health authority approval is only a true ‘win’ if the evidence enables access and adoption into clinical practice. In today's complex and evolving healthcare environment, there is additional strategic evidence generation, communication, and decision support that can benefit from statistical contributions. In this article, we describe the history of medical affairs in the context of drug development, the factors driving post-approval evidence generation needs, and the opportunities for statisticians to optimize evidence generation for stakeholders beyond health authorities in order to ensure that new medicines reach appropriate patients. 相似文献
706.
Alexander Monica Polimis Kivan Zagheni Emilio 《Population research and policy review》2022,41(1):1-28
Population Research and Policy Review - Measuring and forecasting migration patterns has important implications for understanding broader population trends, for designing policy effectively and for... 相似文献
707.
We study the economic determinants of transaction fees in the Ethereum blockchain. We estimate an empirical model based on queueing theory and analyze the factors determining the “gas price” (transaction cost per unit of service, “gas”). Using block- and transaction-level data from the Ethereum blockchain, we show that changes in service demand significantly affect the gas price—when there is high block utilization, per-unit fees increase on average, with strong nonlinear effect above 90% utilization. The transaction type is another important factor—larger fraction of regular transactions (direct transfers between users) is associated with higher gas price. 相似文献
708.
Jennifer Alexander 《The Asia Pacific Journal of Anthropology》2018,19(3):264-280
This analysis of changing perceptions of ethnic identity in Sarawak revolves around migration and imagination. The research is based on a case study of one longhouse, Levu Lahanan, and its imagined community from the mid-1980s on the Balui River to their resettlement in the Bakun Resettlement Scheme in 1999. One of fifteen longhouse communities belonging to five different ethnic groups, they were resettled to make way for Bakun Dam, which was completed in 2012. My use of the term imagination is linked to Sarawak state planning in organising the staged migration of the fifteen longhouse communities, the appeal to emerging Christian communities by calling the operation Exodus, and the exercise in salvage ethnography by recording oral histories, songs and other evidence of migration and difference. My argument is linked to recent developments in communication technology in the form of Facebook, WhatsApp and mobile phones which link the Lahanan longhouse and its urban and international diasporas. In their imagination, if not in reality, members of the diaspora return to their apartments of origin to revive their sense of belonging to a longhouse community, a place and an ethnic identity in a time of state, national and global change. 相似文献
709.
William M. Alexander 《Social Studies》2013,104(2):60-62
Although much energy has been spent designing children's books and curriculum to bring issues of diversity and acceptance into classrooms, perhaps the most meaningful and relevant curricular materials only require a digital camera and a space for students to talk about photos of their own classroom community, creating an organic and everyday curriculum. From over three years of research in a preschool classroom, the researcher-author tells how she uses digital photography to allow students to examine and reimagine their own social community. She revives the pedagogies of seminal social educators like Vivian Paley and Fannie Shaftel while offering a photo methodology for researchers of children who are interested in better understanding children's peer culture. As play is perhaps the most important vehicle of social education, carving out a time and space in the school day for a reflective component with digital photography can be an interesting and empowering way for children to examine social dilemmas and confront inequities. 相似文献
710.
Abstract This paper examines how elite newspaper editorials and opinion pieces (hereafter collectively called op-eds) debated the attack on Iraq. The period examined was the two months preceding Congress's October 2002 authorization of the use of force against Iraq. The 292 op-ed pieces examined represent one of the most extensive looks at such op-ed activity in the United States. There were several major findings. First, contrary to some liberal charges, the commentary overall was more critical than supportive of the administration. On the other side, however, if the elite press was not slavishly supportive of U.S. foreign policy, its criticisms were also rather muted. Supported therefore is the view that the elite media keep respectable opinion on foreign policy within a narrow range that excludes the most damaging criticism. Most notably missing from the print debate on Iraq in this period was much objection to the attack on specifically legal or moral grounds. The avoidance by the elite press of legal and moral language arguably helped convey the general impression that no legal or moral considerations were at stake. At the very least, it is shown, this sector of the public sphere did little to help the nation as a whole to deliberate morally about war. 相似文献