The "experimenting agency". The California Youth Authority Research Division

During the 1960s and 1970s, the California Youth Authority embarked on a series of randomized field trials to test interventions for juvenile and young adult offenders. This article examines the institutional and political reasons why rigorous tests were adopted for such interventions as the Community Treatment Program. It also describes the effect these trials had on the agency and on California justice, as well as how the experimental method eventually became less often used in the Youth Authority. The authors explore some general reasons why this happened.     

Institutionalization or Decoupling? An Exploratory Analysis of the UN Global Compact LEAD Initiative

Institutionalization occurs when organizations adopt policies and practices in an attempt to increase their legitimacy and competitive position. This process assumes that an organization's formal policies (macro‐level) are translated into organizational practices (micro‐level). This translation, however, can fail to occur, resulting in organizational decoupling and de‐institutionalization. Drawing on an institutionalization typology based on different levels of legitimacy (macro) and taken‐for‐grantedness (micro), the article draws on data from an assessment of the United Nations Global Compact LEAD initiative, assessing the extent to which this initiative is being institutionalized in the member firms and examining the implications for the LEAD initiative and our thinking about institutionalization.     

Hypothesis group testing for disjoint pairs

Classical group testing (CGT) is a widely applicable biotechnical technique used to identify a small number of distinguished objects from a population when the presence of any one of these distinguished objects among a group of others produces an observable result. This paper discusses a variant of CGT called group testing for disjoint pairs (GTAP). The difference between the two is that in GTDP, the distinguished items are pairs from, not individual objects in, the population. There are several biological examples of when this abstract model applies. One biological example is DNA hybridization. The presence of pairs of hybridized DNA strands can be detected in a pool of DNA strands. Another situation is the detection of binding interactions between prey and bait proteins. This paper gives a random pooling method, similar in spirit to hypothesis testing, which identifies pairs of objects from a population that collectively have an observable function. This method is simply to apply, achieves good results, is amenable to automation and can be easily modified to compensate for testing errors. M.A. Bishop is supported by AFOSR FA8750-06-C-0007. A.J. Macula is supported by NSF-0436298, AFOSR FA8750-06-C-0007.     

An Exposure‐Response Threshold for Lung Diseases and Lung Cancer Caused by Crystalline Silica

Whether crystalline silica (CS) exposure increases risk of lung cancer in humans without silicosis, and, if so, whether the exposure‐response relation has a threshold, have been much debated. Epidemiological evidence is ambiguous and conflicting. Experimental data show that high levels of CS cause lung cancer in rats, although not in other species, including mice, guinea pigs, or hamsters; but the relevance of such animal data to humans has been uncertain. This article applies recent insights into the toxicology of lung diseases caused by poorly soluble particles (PSPs), and by CS in particular, to model the exposure‐response relation between CS and risk of lung pathologies such as chronic inflammation, silicosis, fibrosis, and lung cancer. An inflammatory mode of action is described, having substantial empirical support, in which exposure increases alveolar macrophages and neutrophils in the alveolar epithelium, leading to increased reactive oxygen species (ROS) and nitrogen species (RNS), pro‐inflammatory mediators such as TNF‐alpha, and eventual damage to lung tissue and epithelial hyperplasia, resulting in fibrosis and increased lung cancer risk among silicotics. This mode of action involves several positive feedback loops. Exposures that increase the gain factors around such loops can create a disease state with elevated levels of ROS, TNF‐alpha, TGF‐beta, alveolar macrophages, and neutrophils. This mechanism implies a “tipping point” threshold for the exposure‐response relation. Applying this new model to epidemiological data, we conclude that current permissible exposure levels, on the order of 0.1 mg/m³, are probably below the threshold for triggering lung diseases in humans.     

Becoming an American and Liking It as Functions of Social Distance and Severity of Initiation

This paper examines the effects of social distance among a sample of immigrants in the process of becoming United States citizens. Using the Bogardus Social Distance Scale, a positive relationship was found between the degree of social distance and the likelihood of becoming a citizen. Social distance also serves as an important indicator of severity of initiation; the findings suggest that severity of initiation had a positive influence on reported satisfaction with life in America for those who became U. S. citizens. For those who did not become citizens, however, social distance had an inverse affect on satisfaction.     

CALIBRATING MEASURES OF FAMILY ACTIVITIES BETWEEN LARGE- AND SMALL-SCALE DATA SETS

Two studies of working families are combined to demonstrate a strategy for producing reliable estimates from the combination of self-reported (large N) and observational (small N) data. Both studies examine where and how dual-career families spend time at home. The 500 Family Study is sociological and uses self-reported time diary data from a national sample; the CELF study is anthropological and uses observational scan sampling data from a regional sample of 32 families. The data are combined as if they constitute one sample, and an analytic solution for establishing the reliability of the resulting composite estimates of time use is provided. Merging the data sets provides validation for each study, neither of which is without potential methodological weaknesses. The advantages of combining data from the independent data collection methods are discussed, and selected substantive findings on families' activities are highlighted, illustrating similarities and differences between findings in the independent and combined data sets. Results show that working families spend significant time in a small spectrum of home spaces, particularly kitchens and living rooms, with leisure activities prevailing, but mothers, fathers, and children differ in where and how they spend their time. Overall, a template for merging data from different disciplines and methods is provided.     

Domestic Violence Service Providers’ Needs and Perceptions of Technology: A Qualitative Study

There is growing recognition of the need to better understand the intersections between the work of domestic violence service providers and technology. Professionals who work with clients impacted by domestic violence are increasingly using technologies across different aspects of their work, including communicating with other professionals and seeking information and resources via the Internet. The current study used qualitative data from two sources—individual interviews and two focus groups—to learn about domestic violence service providers’ needs and perceptions related to technology use. The results provide insights about technologies used currently, expected benefits of future technological advances, barriers to using technology, and participants’ self-rated levels of comfort with technology.