Are Private Interests Clouding the Peer-Review Process of the WHO Bulletin? A Case Study

Readers’ trust on the medical literature has been eroded, and journal editors and some editorial boards are taking measures to ensure that authors fully and accurately report research findings and disclose conflicts of interest. This article describes a case study in which the papers editor of the World Health Organization (WHO) Bulletin influenced the content of an article that had been approved by the external reviewers. The editor objected to the publication of the large price differentials of the new molecular entities (NMEs) across the Latin American countries where they had been tested and the limited added therapeutic value of the NMEs that had been assessed by independent drug bulletins. This article summarizes the exchanges with WHO staff and posits the hypothesis that the WHO Bulletin might be affected by the shifts in WHO financing. Several authors have raised concern about the impact of financial conflicts of interest in WHO activities in the field of nutrition, intellectual property, and in the emergency response to the flu pandemic. Moreover, it has been reported that powerful WHO contributors pressured WHO into revising its publication policy. This is the first time that authors question if these conflicts of interest are also affecting the editorial independence of the WHO Bulletin.     

Statistical concepts of a priori and a posteriori risk classification in insurance

Everyday we face all kinds of risks, and insurance is in the business of providing us a means to transfer or share these risks, usually to eliminate or reduce the resulting financial burden, in exchange for a predetermined price or tariff. Actuaries are considered professional experts in the economic assessment of uncertain events, and equipped with many statistical tools for analytics, they help formulate a fair and reasonable tariff associated with these risks. An important part of the process of establishing fair insurance tariffs is risk classification, which involves the grouping of risks into various classes that share a homogeneous set of characteristics allowing the actuary to reasonably price discriminate. This article is a survey paper on the statistical tools for risk classification used in insurance. Because of recent availability of more complex data in the industry together with the technology to analyze these data, we additionally discuss modern techniques that have recently emerged in the statistics discipline and can be used for risk classification. While several of the illustrations discussed in the paper focus on general, or non-life, insurance, several of the principles we examine can be similarly applied to life insurance. Furthermore, we also distinguish between a priori and a posteriori ratemaking. The former is a process which forms the basis for ratemaking when a policyholder is new and insufficient information may be available. The latter process uses additional historical information about policyholder claims when this becomes available. In effect, the resulting a posteriori premium allows one to correct and adjust the previous a priori premium making the price discrimination even more fair and reasonable.     

A social policy model for the reconciliation of employment and family life from a gender equality perspective

The issue of family–employment reconciliation has rapidly evolved from being ignored to a certain dejá vu perception in public debate, as a result of its media success during the last decade. This is even more the case in Spain, where it was only in the late 1990s, when a law was passed to regulate and extend parental and other leave for workers with close relatives in need of care, that reconciliation policies began to be generally discussed and considered. In a context of quick population aging as a consequence of low fertility, concern on labor force supply in the middle term is high on the agenda. Women are increasingly considered to be necessary both as workers and mothers (of future workers), thus raising awareness of the importance of social policies to make their double presence in both worlds possible. There is now general agreement from the right to the left on the urgency to develop family–employment policies. But what is not generally addressed is the impact of such policies on gender equality, a dimension which tends to be either ignored or taken for granted. Not all reconciliation measures have the same effects on the women and men relationship. Some of them push forward equality, whereas others go backwards. Efficiency in making job and family responsibilities compatible does not always go hand in hand with increasing equality. The paper presents a theoretical model for the reconciliation of work and family life from a gender equality perspective. The three main kinds of instruments available in social policy – services, leave, and cash – are examined in four different cases: care of under-threes, care of sick children, coordination of work and school schedules, and care of children during school holidays. Each case is looked at considering its effects on social and gender equality, as well as child welfare. The model includes as active agents of the system the State (promotes and regulates), families and individuals (those directly implicated), and the market as labor market, on the one hand, and supplier of private services, on the other.     

Long-term Growth Perspectives and Economic Convergence of CEE and SEE Countries

The paper first investigates the main drivers of economic growth and real convergence in CEE and SEE Countries. In the theoretical framework provided by the growth-accounting approach, both are shown to be driven by capital accumulation and total factor productivity changes, with the latter making however a major contribution. The nominal convergence path towards the Eurozone is then analysed. Despite considerable results obtained in the last decade, most EU new members are still found to face severe challenges in the process of converging towards Maastricht criteria. The need to reconcile exchange rate stability with inflation convergence is in particular seen to be at the heart of their de facto decision to delay the EMU entry date until a higher degree of real convergence will have been achieved.

The effect of corporate governance on sustainability disclosure

Drawing on stakeholder theory, this paper examines the relationship of board composition, leadership and structure on sustainability disclosure. We discuss that good corporate governance and sustainability disclosure can be seen as complementary mechanisms of legitimacy that companies may use to dialogue with stakeholders. Specifically we claim that, as disclosure policies emanate from the board of directors, sustainability disclosure may be a function of the board attributes: we investigate the relationship between different characteristics of the board and sustainability disclosures among US and European companies. Our results show that in order to explain the effect of board composition on sustainability disclosure we need to go beyond the narrow and traditional distinction between insider and independent directors, focusing on the specific characteristics of each director.     

Application of an Irt Polytomous Model for Measuring Health Related Quality of Life

Background: The Item Response Theory (IRT) has advantages for measuring Health Related Quality of Life (HRQOL) as opposed to the Classical Tests Theory (CTT). Objectives: To present the results of the application of a polytomous model based on IRT, specifically, the Rating Scale Model (RSM), to measure HRQOL with the EORTC QLQ-C30. Methods: 103 terminal cancer patients cared for by the home services of the Servicio Andaluz de Salud (Andalusian Health Service) (Andalusia, Spain) participated. These patients responded to the adapted Spanish version of the EORTC QLQ-C30. The application was carried out individually in the patients’ homes. Results: The results show that there is an adequate global fit between the data and the IRT model applied. The analysis of the items shows that for 31 of the 33 items there is a good fit. The items which measure the general perception of health and the perception of quality of life present a lack of fit. The study of the response categories of the items (by means of Category Probability Curves) indicates that all the alternatives work extremely well. Conclusions:The EORTC QLQ-C30 presents good metric qualities, under the RSM, ratifying the feasibility to measure HRQOL already shown in other studies carried out with CTT.     

Critical success factors in managing modular production design: Six company case studies in Hong Kong, China, and Singapore

Many researchers have explored the advantages of modular product design, its design methods and its effects on product performance. Modular design is, for example, required for product platform, mass customization and postponement in order to achieve greater product variety and differentiation. However, a few empirical studies explicitly examine how to coordinate modular product design in a managerial way. This paper addresses it by conducting multiple case studies with six companies which have successfully adopted modular product design for five years. Seven critical factors are explored in the management of modular product design. These are pre-defined product advantage, selectively used design rules, module definition, system integration, technological newness, internal communication, and supplier and customer involvement. While most of the literature studies the technical dimension of modular design within a firm, this study focuses on the managerial side across the supply chain. It gives new insights on how to manage modular product design and proposes future research opportunities.     

Hazards of neoliberalism: delayed electric power restoration after Hurricane Ike

This case study explores how neoliberal policies shape the impacts of a natural disaster. We investigate the reactions to major damages to the electric power system and the restoration of power in the wake of Hurricane Ike, which devastated the Houston, Texas, metropolitan area in September 2008. We argue that the neoliberal policy agenda insured a minimalist approach to the crisis and generated dissatisfaction among many residents. The short-term profitability imperative shifted reconstruction costs to consumers, and prevented efforts to upgrade the electric power infrastructure to prepare for future disasters. We illustrate the serious obstacles for disaster mitigation and recovery posed by neoliberal policies that privatize public goods and socialize private costs. Neoliberalism neither addresses the needs of a highly stratified public nor their long-term interests and safety.     

Affective and Cognitive Correlates of Gambling Behavior in University Students

The purpose of the following study was to explore certain affective and cognitive components and their relationships to gambling behavior in an undergraduate population. Specifically, the aim was to predict gambling severity using depression scores on the BDI-II, the dependency and self-criticism subscales on the DEQ, emotional awareness scores on the LEAS, cognitive flexibility scores from the STROOP, and a creativity subtests from the TTCT. Participants were 200 undergraduate students and 3.5–7.5% of individuals reported some level of problematic gambling behavior. Multiple regression analysis indicated that self-criticism and creative originality were significant predictors of gambling behavior, explaining 7.6% of the variance. Further analyses reveal a non-linear trend in the creative originality of those who gamble; only the at-risk gamblers were high in creativity whereas abstainers and problematic gamblers display similarly lower levels of creativity. Results are discussed in regards to Blaszczynski and Nower’s Addiction 97:487–499 (2002) subtypes of gambling vulnerability.