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11.
This article describes how a frequentist model averaging approach can be used for concentration–QT analyses in the context of thorough QTc studies. Based on simulations, we have concluded that starting from three candidate model families (linear, exponential, and Emax) the model averaging approach leads to treatment effect estimates that are quite robust with respect to the control of the type I error in nearly all simulated scenarios; in particular, with the model averaging approach, the type I error appears less sensitive to model misspecification than the widely used linear model. We noticed also few differences in terms of performance between the model averaging approach and the more classical model selection approach, but we believe that, despite both can be recommended in practice, the model averaging approach can be more appealing because of some deficiencies of model selection approach pointed out in the literature. We think that a model averaging or model selection approach should be systematically considered for conducting concentration–QT analyses. Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
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This study examined maternal perceptions of their child's response to the medical evaluation for alleged sexual abuse. A total of 50 mothers were interviewed 6 months after a visit to a Child Protection Clinic for a medical evaluation of alleged sexual abuse. The mothers answered a questionnaire on their child's reactions to the medical visit. More than 60% of children were perceived as being reassured about physical integrity. The degree of psychological distress was independent of perpetrator's identity and severity of the abuse. Mothers considered that a hypothetical second visit would generate in their child a level of anxiety that increased with perceived intensity of fear of the examination and decreased with perceived kindness of the physician. These results suggest that the physician's behaviour during the medical evaluation for alleged sexual abuse has an influence on the child's degree of distress that is independent of type and severity of abuse. Copyright © 2001 John Wiley & Sons, Ltd.  相似文献   
14.
Fortune     
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15.
Traditionally, the moments of the Weibull distribution have been calculated using the standard Weibull (Johnson and Kotz, 1970) . This article will expand on that idea and cover the truncated cases for the standard Weibull distributions. Also, the same techniques used for the standard form will be used to derive the moment expressions for the three-parameter complete and truncated Weibull distributions. The summary statistics are then calculated from the moment expressions. Weibull moments involve the gamma and incomplete gamma functions.  相似文献   
16.
This study expands immigrant social network theory and examined employment patterns in the garment industry in Los Angeles, California, among Latino workers employed by Asian immigrant entrepreneurs. The study determined that a large percentage of immigrant employees found their jobs through the immigrant economy. Entrepreneurship increased the supply of local jobs and expanded the economy at destination at no expense to natives. Immigrant entrepreneurs bought firms from nonimmigrant owners or started new ones with an immigrant labor supply. Massey's index is flawed due to its exclusion of the role of entrepreneurs. Migration networks facilitate entrepreneurship, but some ethnic groups have fewer entrepreneurs, such as Mexicans and Central Americans. A 1993 Los Angeles survey identified 3642 garment factories in its county. Mean employment was 27.1 persons. The garment industry was the 4th largest industry in the area in 1996, with 98,700 employees. It represented 6% of all wage and salary employees in the City and 5.5% of the immigrant labor force in the County in 1990. 93% of garment workers in 1990 were immigrants. It is estimated that 51% of garment factory owners were Asians; most employees were Latinos. Census figures on sewing machine operators indicated 47.3% of owners were Whites and 42.45 were Asians. 53.3% of employees were other ethnic groups, 14.5% were Asians, and 32.2% were Whites. It is estimated that 47.2% of total employment was due to the immigration economy. 71.5% of the total employment in the garment industry was in the immigrant sector.  相似文献   
17.
In this paper we consider the three classes of choice functions satisfying the three significant axioms called heredity (H), concordance (C) and outcast (O). We show that the set of choice functions satisfying any one of these axioms is a lattice, and we study the properties of these lattices. The lattice of choice functions satisfying (H) is distributive, whereas the lattice of choice functions verifying (C) is atomistic and lower bounded, and so has many properties. On the contrary, the lattice of choice functions satisfying (O) is not even ranked. Then using results of the axiomatic and metric latticial theories of consensus as well as the properties of our three lattices of choice functions, we get results to aggregate profiles of such choice functions into one (or several) collective choice function(s).The authors thank two anonymous referee for several useful remarks or corrections on the first version of the paper.  相似文献   
18.
Family Therapy with the Learning Disabled Child and His/Her Family   总被引:1,自引:0,他引:1  
No therapist can come in contact with and treat children with minimal brain damage or specific learning disabilities without being struck by the fact that there are numerous intertwined factors that have contributed to and continue to perpetuate the problems. In addition to the helping approaches which have been utilized in recent years, such as tutoring, special education, and child therapy, this article elaborates the importance of utilizing family therapy as the treatment of choice sometime during the course of treating the child and helping the parents to understand and deal with their handicapped youngster.  相似文献   
19.
We consider the problem of orienting the edges of a graph so that the length of a longest path in the resulting digraph is minimum. As shown by Gallai, Roy and Vitaver, this edge orienting problem is equivalent to finding the chromatic number of a graph. We study various properties of edge orienting methods in the context of local search for graph coloring. We then exploit these properties to derive four tabu search algorithms, each based on a different neighborhood. We compare these algorithms numerically to determine which are the most promising and to give potential research directions.  相似文献   
20.

A method for evaluating the robustness of medium term multisite distributed schedule is presented. The method of robustness evaluation is based on steps and tools associated with the conceptual model of a MultiSite Reactive Production Activity Control (MSR-PAC). The MSR-PAC makes it possible to study the sensitivity of the scheduled plans in presence of perturbations. These must be evaluated before being dispatched to the shop-floors. At present, to the best of the authors' knowledge, there is no means to make this evaluation in the distributed systems such as extended enterprise. The monitoring of errors is based on the discrepancy between the two flow-shape functions that model respectively the dynamics of the scheduled manufacturing orders and the state of the perturbed production. The MSR-PAC is based on a multisite agent system and on the monitoring of the perturbed virtual jobshops. The method can also be used for controlling short term distributed production activities.  相似文献   
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