New Developments in Statistical Computing: New Bias Evaluation Features of EXPLOR—A Program for Assessing Experimental Design Properties

Longitudinal investigations play an increasingly prominent role in biomedical research. Much of the literature on specifying and fitting linear models for serial measurements uses methods based on the standard multivariate linear model. This article proposes a more flexible approach that permits specification of the expected response as an arbitrary linear function of fixed and time-varying covariates so that mean-value functions can be derived from subject matter considerations rather than methodological constraints. Three families of models for the covariance function are discussed: multivariate, autoregressive, and random effects. Illustrations demonstrate the flexibility and utility of the proposed approach to longitudinal analysis.     

Developing “A Framework for Planning U.S. Federal Statistics, 1978–1989”

The Statistical Policy Division of the Office of Management and Budget has the overall responsibility for the planning and coordination of U.S. government statistics. The present staff of the Statistical Policy Division is attempting, through an integrated publication entitled “A Framework for Planning U.S. Federal Statistics, 1978–1989,” to state its perspective on necessary developments in the coming years. This article illustrates the character of the Framework materials and outlines the process for public review and comment on this undertaking.     

Use of the Correlation Coefficient with Normal Probability Plots

The use of the correlation coefficient is suggested as a technique for summarizing and objectively evaluating the information contained in probability plots. Goodness-of-fit tests are constructed using this technique for several commonly used plotting positions for the normal distribution. Empirical sampling methods are used to construct the null distribution for these tests, which are then compared on the basis of power against certain nonnormal alternatives. Commonly used regression tests of fit are also included in the comparisons. The results indicate that use of the plotting position p_i = (i - .375)/(n + .25) yields a competitive regression test of fit for normality.     

The Role of Statistical Models in the Prediction of Tropical Cyclone Motion

Tropical cyclones (tropical storms, hurricanes, typhoons, etc.) occur over many of the earth's tropical marine areas. Responsibility for tracking and predicting the future course of these storms is assigned to one or more domestic or foreign meteorological services. These services routinely activate a number of statistical and dynamical prediction models as objective guidance preparatory to issuing official forecasts on these storms. In this article, the role of the statistical models in this process is examined.     

A Comparison of Large-Sample Confidence Interval Methods for the Difference of Two Binomial Probabilities

A simulation study was done to compare seven confidence interval methods, based on the normal approximation, for the difference of two binomial probabilities. Cases considered included minimum expected cell sizes ranging from 2 to 15 and smallest group sizes (NMIN) ranging from 6 to 100. Our recommendation is to use a continuity correction of 1/(2 NMIN) combined with the use of (N ? 1) rather than N in the estimate of the standard error. For all of the cases considered with minimum expected cell size of at least 3, this method gave coverage probabilities close to or greater than the nominal 90% and 95%. The Yates method is also acceptable, but it is slightly more conservative. At the other extreme, the usual method (with no continuity correction) does not provide adequate coverage even at the larger sample sizes. For the 99% intervals, our recommended method and the Yates correction performed equally well and are reasonable for minimum expected cell sizes of at least 5. None of the methods performed consistently well for a minimum expected cell size of 2.     

Manipulating Statistical Hypotheses and Tests as Boolean Functions

Statistical hypotheses and test statistics are Boolean functions that can be manipulated using the tools of Boolean algebra. These tools are particularly useful for exploring multiple comparisons or simultaneous inference theory, in which multiparameter hypotheses or multiparameter test statistics may be decomposed into combinations of uniparameter hypotheses or uniparameter tests. These concepts are illustrated with both finite and infinite decompositions of familiar multiparameter hypotheses and tests. The corresponding decompositions of acceptance regions and rejection regions are also shown. Finally, the close relationship between hypothesis and test decompositions and Roy's union—intersection principle is demonstrated by a derivation of the union—intersection test of the univariate general linear hypothesis.     

LogXact 4.1 for Windows

Box's paper helicopter has been used to teach experimental design for more than a decade. It is simple, inexpensive, and provides real data for an involved, multifactor experiment. Unfortunately it can also further an all-too-common practice that Professor Box himself has repeatedly cautioned against, namely ignoring the fundamental science while rushing to solve problems that may not be sufficiently understood. Often this slighting of the science so as to get on with the statistics is justified by referring to Box's oft-quoted maxim that “All models are wrong, however some are useful.” Nevertheless, what is equally true, to paraphrase both Professor Box and George Orwell, is that “All models are wrong, but some are more wrong than others.” To experiment effectively it is necessary to understand the relevant science so as to distinguish between what is usefully wrong, and what is dangerously wrong.

This article presents an improved analysis of Box's helicopter problem relying on statistical and engineering knowledge and shows that this leads to an enhanced paper helicopter, requiring fewer experimental trails and achieving superior performance. In fact, of the 20 experimental trials run for validation—10 each of the proposed aerodynamic design and the conventional full factorial optimum—the longest 10 flight times all belong to the aerodynamic optimum, while the shortest 10 all belong to the conventional full factorial optimum. I further discuss how ancillary engineering knowledge can be incorporated into thinking about—and teaching—experimental design.     

An Improved Boxplot for Univariate Data

The boxplot is an effective data-visualization tool useful in diverse applications and disciplines. Although more sophisticated graphical methods exist, the boxplot remains relevant due to its simplicity, interpretability, and usefulness, even in the age of big data. This article highlights the origins and developments of the boxplot that is now widely viewed as an industry standard as well as its inherent limitations when dealing with data from skewed distributions, particularly when detecting outliers. The proposed Ratio-Skewed boxplot is shown to be practical and suitable for outlier labeling across several parametric distributions.