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71.
Experimental research suggests the differentiation of ‘nice’ and ‘nasty’ theory of mind (ToM). Over 5000 parents from the Twins Early Development Study reported on nice (e.g., being considerate) and nasty (e.g., blaming others) behaviours following their twins’ second, third, and fourth birthdays. Factor analyses yielded four factors and it was proposed that these related to prosocial behaviour necessitating ToM (Nice ToM), antisocial behaviour necessitating ToM (Nasty ToM), and prosocial and antisocial behaviour not necessitating ToM (Nice and Nasty). Interscale correlations, gender differences, and their relationship with language were consistent with this distinction. Both ToM scales showed moderate heritability and significant environmental influences (shared and nonshared). Bivariate analyses indicated somewhat distinct aetiological influences on Nice ToM versus Nasty ToM. However, further research is needed to confirm whether this distinction reflects interactions between ToM and temperament, or two underlying genetic and cognitively distinct ToM abilities. 相似文献
72.
The non-governmental Foundation for Integrated Assistance tothe Elderly and the Family (FAIAF) in Argentina provides technicalsupport teams which enable groups of elderly people to developartistic, cultural, educational and productive activities; aprincipal objective is the independent functioning of the groups.The method of intervention is described, and the results ofan initial evaluation given. 相似文献
73.
Claire L. Smith Zachary Thomas Nathan Enas Katharine Thorn Michael Lahn Karim Benhadji Ann Cleverly 《Pharmaceutical statistics》2020,19(3):276-290
Leveraging historical data into the design and analysis of phase 2 randomized controlled trials can improve efficiency of drug development programs. Such approaches can reduce sample size without loss of power. Potential issues arise when the current control arm is inconsistent with historical data, which may lead to biased estimates of treatment efficacy, loss of power, or inflated type 1 error. Consideration as to how to borrow historical information is important, and in particular, adjustment for prognostic factors should be considered. This paper will illustrate two motivating case studies of oncology Bayesian augmented control (BAC) trials. In the first example, a glioblastoma study, an informative prior was used for the control arm hazard rate. Sample size savings were 15% to 20% by using a BAC design. In the second example, a pancreatic cancer study, a hierarchical model borrowing method was used, which enabled the extent of borrowing to be determined by consistency of observed study data with historical studies. Supporting Bayesian analyses also adjusted for prognostic factors. Incorporating historical data via Bayesian trial design can provide sample size savings, reduce study duration, and enable a more scientific approach to development of novel therapies by avoiding excess recruitment to a control arm. Various sensitivity analyses are necessary to interpret results. Current industry efforts for data transparency have meaningful implications for access to patient‐level historical data, which, while not critical, is helpful to adjust for potential imbalances in prognostic factors. 相似文献
74.
The United Nations Convention on the Rights of the Child requires that children ‘have the right to be heard in matters affecting them’ (Article 12). Given that planning matters such as housing, transport, services and recreation provision affect children, it is necessary, therefore, for planners to engage with children. While planning has made considerable progress in working with older children, preschool children have been overlooked. Preschoolers are commonly seen as lacking the understanding necessary to comprehend the city scale. This paper presents a tile-based city-mapping method that demonstrates preschool children do understand city-scale features and relationships. Further, this method could be used in planning to advocate for and to engage with very young children in planning conversations. 相似文献
75.
Federica Misturelli Claire Heffernan 《Development policy review : the journal of the Overseas Development Institute》2009,27(2):167-183
Poverty, as defined within development discourse, does not fully capture the reality in which the poor live, which is formed also by values and beliefs specific to a given culture and setting. This article uses a memetic approach to investigating the reality of poverty among pastoralists and urban dwellers in Kenya. By distinguishing the semantic space and the cultural context in which the definitions are framed, it enables the researcher to make sufficient generalisations while also recognising the differences between cultures. The results demonstrate how pastoralists and urban dwellers conceptualise poverty differently particularly in regard to causes. Further, the article suggests that development actors often utilise a Western construct which does not entirely reflect the values and beliefs of the poor. 相似文献
76.
77.
Claire Vermaak 《Journal of Economic Inequality》2012,10(2):239-265
Household surveys often contain coarse data, which consist of a mixture of missing values, interval-censored values and point (fully-observed) values, making it difficult to construct a continuous money-metric measure of wellbeing. This paper assesses the sensitivity of poverty and inequality estimates to the multiple imputation of coarse earnings data and reported zero values using the 2001?C2006 South African Labour Force Surveys. Estimates of poverty amongst the employed are shown not to be sensitive to multiple imputation of missing and interval-censored data, but are sensitive to the treatment of workers reporting zero earnings. Poverty trends are generally robust to the choice of method, and a significant decline in poverty is evident. Inequality estimates, on the other hand, appear more sensitive to the treatment of zero values and the choice of imputation methods, and, overall, no particular trends in inequality could be discerned. 相似文献
78.
By the end of their first year of life, infants’ representations of familiar words contain phonetic detail; yet little is known about the nature of these representations at the very beginning of word learning. Bouchon et al. ( 2015 ) showed that French‐learning 5‐month‐olds could detect a vowel change in their own name and not a consonant change, but also that infants reacted to the acoustic distance between vowels. Here, we tested British English‐learning 5‐month‐olds in a similar study to examine whether the acoustic/phonological characteristics of the native language shape the nature of the acoustic/phonetic cues that infants pay attention to. In the first experiment, British English‐learning infants failed to recognize their own name compared to a mispronunciation of initial consonant (e.g., Molly versus Nolly) or vowel (e.g., April versus Ipril). Yet in the second experiment, they did so when the contrasted name was phonetically dissimilar (e.g., Sophie versus Amber). Differences in phoneme category (stops versus continuants) between the correct consonant versus the incorrect one significantly predicted infants’ own name recognition in the first experiment. Altogether, these data suggest that infants might enter into a phonetic mode of processing through different paths depending on the acoustic characteristics of their native language. 相似文献
79.
This paper introduces several theoretical constructs drawn from the work of Humberto Maturana that can be applied to a diverse range of clinical contexts, including supervision. These constructs are: love as a fundamental need of human beings; pathways of explanation: (Objectivity), Objectivity; Emotioning; Structural Coupling; Plasticity; Domains of Operational Coherences. These constructs assist in choosing a point of entry for specific clinical situations and form a foundation on which one's preferred model of practice can be built. 相似文献
80.
Explanations for type 2 diabetes are broadened beyond the individual body and ‘bad lifestyles’ to include major institutions, the social and material contexts of food and eating, and employment. Precarious employment, a social determinant of health, encourages changes to food practices, lowers working conditions, worsens health, can bring poverty and increases shift work, a causal risk factor for diabetes. Scientists have played a part in revolutionising foods and technologies which minimise labour and movement. There are excess additives in processed food. Genetic explanations for the higher rates of diabetes in First Nations peoples give way to social explanations: colonial history, British/Euro‐American cuisine, food insecurity, trauma and social conditions resulting in chronic stress. Self‐management education takes a ‘nutritionist’ approach towards food and eating and tends to minimise the social context and skills of those with the condition particularly women workers in poorer social groups who have higher rates of diabetes (T2DM). 相似文献