An intuitive risk factors search algorithm: usage of the Bayesian network technique in personalized medicine

The article focuses on the application of the Bayesian networks (BN) technique to problems of personalized medicine. The simple (intuitive) algorithm of BN optimization with respect to the number of nodes using naive network topology is developed. This algorithm allows to increase the BN prediction quality and to identify the most important variables of the network. The parallel program implementing the algorithm has demonstrated good scalability with an increase in the computational cores number, and it can be applied to the large patients database containing thousands of variables. This program is applied for the prediction for the unfavorable outcome of coronary artery disease (CAD) for patients who survived the acute coronary syndrome (ACS). As a result, the quality of the predictions of the investigated networks was significantly improved and the most important risk factors were detected. The significance of the tumor necrosis factor-alpha gene polymorphism for the prediction of the unfavorable outcome of CAD for patients survived after ACS was revealed for the first time.     

Fatalism and Well-Being Across Hispanic Cultures: The Social Fatalism Scales (SFS)

Social Indicators Research - Fatalism has been a core construct in the study of psychological and social processes related to well-being and life quality in social sciences. The objective of the...     

Islamic Jurisprudence of Minorities (Fiqh al-Aqalliyyat): The Case of the Palestinian Muslim Minority in Israel

This article examines the doctrine of Jurisprudence of Muslim Minorities (Fiqh al-Aqalliyyat) in the context of the Palestinian Muslim community in Israel. The first part discusses the origins and goals of Fiqh al-Aqalliyyat. After outlining the particular historical and political context of the Palestinian minority in Israel, the article focuses on the ethno-religious political mobilization developed by the Muslim community vis-à-vis the state’s strategies of control and domination, and points out the difficulties involved in the application of Fiqh al-Aqalliyyat, as used in “Western” states, for the reality that Muslims face in Israel. The article suggests a vigilant approach toward the Jurisprudence of Minorities, as we argue that, when applying it in this context of the Muslim community in Israel, this doctrine has two substantial limitations. The first is theoretical and it concerns the doctrine’s current incapability to distinguish between different types of minorities, as well as failing to recognize a difference between various political regimes and societal lives that might be inherently less or more accommodating or even hostile to minorities, and Muslim minority communities in particular. The second limitation relates to the political dimension and the lack of consideration for the status of the Palestinian minority as an indigenous and national minority and not an immigrant minority. Their status as national minorities, at times also as indigenous peoples, who are perceived as entitled to group-based “self-government rights”, poses a serious challenge to this doctrine’s scope and viability.     

Family Structure and Children’s Economic Well-Being: Incorporating Same-Sex Cohabiting Mother Families

Research on family structure and child well-being rarely includes children in same-sex parent families, a notable omission since 28 % of female–female couple households contain children. Using the 2010–2013 pooled current population survey (CPS), we examined children’s economic well-being by family structure. These data were ideal for this study because they included a sizeable number of children in same-sex cohabiting mother families and the CPS measured both official and supplemental poverty, incorporating the cohabiting partner. Using the official poverty measure, children in same-sex cohabiting mother families were more likely to be poor than their counterparts in either different-sex cohabiting or married parent families. Using the supplemental poverty measure, children in same-sex mother families were no more likely to be poor than children in all other types of different-sex two-parent families.     

MOTHER'S EMPLOYMENT DEMANDS, WORK-FAMILY CONFLICT, AND ADOLESCENT DEVELOPMENT

This study revisited the old research question of whether or not maternal employment would adversely affect children's development. We reframed the question by asking how a mother's temporal employment demands might be linked to child development. We used longitudinal data from a sample of 340 white, lower- to middle-class, dual-earner families living in the rural Midwest of the United States. The data were obtained from questionnaires and videotaped observations, and were informed by the mother, the father, the adolescent child, and a trained observer. As predicted, we found a strong relationship between a mother's temporal employment demands and work-family conflict, which was significantly associated with her emotional distress. A husband's egalitarian gender ideology was found to reduce the mother's emotional distress. Maternal distress was then negatively associated with nurturant and involved parenting, which in turn predicted a reduction in the adolescent child's emotional and behavioral problems over time.     

An Empirical Examination of Characteristics of Mexican Migrants to Metropolitan and Nonmetropolitan Areas of the United States*

Abstract This research examines differences between those Mexican migrants choosing metropolitan destinations and those choosing destinations outside metropolitan areas of the United States. Using general estimating equations, the study presents data indicating that since the 1960s migrants choosing rural destinations are less fluent in English, slightly older, much less educated, far more likely to be unskilled, more likely to be married, and more likely to be undocumented. The picture is more complex when consideration is restricted to those migrants arriving in rural areas since the passage of the North American Free Trade Agreement. These migrants are far more likely to be single, have more education but have less English fluency, have less work experience, and have less family experience with migration to the United States. They are more likely to come from small towns and rural areas of Mexico.     

Humorous Assaults on Patriarchal Ideology*

Humor is a significant weapon in interpersonal and intergroup conflict and competition. Over the centuries, males have used humor and jokes to create and perpetuate patriarchal ideals, relationships, and structures. Today, feminists and other proponents of gender equality use humor to deconstruct patriarchal ideologies and sexist stereotypes. This exploratory study analyzes a collection of over 1,700 jokes identified as feminist and women's humor to discover what these jokes suggest with regard to the male‐dominant structure in society and how these jokes are subversive in attempting to disrupt gender stereotypes and roles. We find that the humor of women and feminists seeks, in part, to discredit assumptions of males’ superiority, masterfulness, sexual prowess, and extraordinary value to women and society. These jokes may, however, also work to reinforce stereotypes associated with men and women: “If they could send a man to the moon, why not just send all of them?”     

DNA COLLECTION IN A RANDOMIZED SOCIAL SCIENCE STUDY OF COLLEGE PEER EFFECTS

We describe the DNA collection processes of an initial pilot and full study, which is designed to investigate joint peer and genetic effects on health behaviors and attitudes in a college campus setting. In the main study, 2664 (79.5%) students completed a Web survey and 2080 (78.7% of the survey completers after adjusting for the ineligible) provided a saliva DNA sample. The response rate for completing both the survey and the DNA portion of the study is 62.5%. Our DNA yields are of high quality. Overall, our experiences and results demonstrate that genetic data can be successfully collected as a part of traditional social science survey research projects. To aid others in doing so, we provide extensive details of our data collection experiences and offer recommendations to future researchers seeking to do or evaluate similar work.