Impact of physical activity and sedentary behaviour on fall risks in older people: a systematic review and meta-analysis of observational studies

The objective of this work was to summarise and evaluate the evidence showing that physical activity is a protector factor as regards falls in older people. Relevant studies were identified through a systematic search in the MEDLINE and Cochrane Library, under the keywords of accidental fall/numerical data and risk factors, and with the bibliographies of retrieved papers. The combined odds ratio (OR) [95% confidence interval] for physical activity was 0.75 [0.64, 0.88] with moderate heterogeneity (I ²?=?33%). For fall injury, it was 0.59 [0.47, 0.74] and, for falls in general, it rose to 0.94 [0.76, 1.17] with nil heterogeneity. The combined OR for sedentary factors was 1.14 [1.10, 1.82] with moderate heterogeneity (I ²?=?36%). Regular physical activity in daily life yields significant reduction in falls in older people, especially falls with injuries.     

Unaddressed problems and research perspectives in scheduling blood collection from donors

Many optimisation problems arise in managing the Blood Donation (BD) supply chain. Most of them have been addressed in the literature, while other problems, e.g. donation scheduling, have not been sufficiently addressed so far. However, blood collection from donors may have a disruptive impact on the entire BD supply chain if not properly managed. For example, scheduling donation appointments based on some system metrics may improve the flow of blood units through the BD supply chain and increase the quality of service perceived by donors. In this short communication, we present the donation scheduling problem and highlight the lack of work in the literature that deals with this problem. Then, we analyse the impact of an unbalanced flow of blood units on the BD system and the benefits that may derive from a suitable appointment scheduling. Finally, we propose suggestions for future research in BD collection scheduling that may improve the BD process.     

« Comment ? Vous n’avez pas de projet ? » : ethnographie du démarchage en matière de crédit à la consommation

Many a product and service is proposed to consumers who have not individually expressed any prior interest to a salesperson or a firm. Two situations of prospecting people for a revolving credit are presented. Based on data gathered during a month of observation in the company of salespersons who deal in this type of credit, the processes are analyzed that these persons use to arouse a potential buyer's interest. Light is shed on the organizational, material and technical conditions that enable them to turn the latter into a customer or, at least, to make interactions with him/her last longer. This analysis of one form of mediation in the marketing of credit also sheds light on the situations of those who subscribe to loans, whether or not they are over indebted.     

Using Eye Tracking to Identify Faking Attempts During Penile Plethysmography Assessment

Penile plethysmography (PPG) is considered the most rigorous method for sexual interest assessment. Nevertheless, it is subject to faking attempts by participants, which compromises the internal validity of the instrument. To date, various attempts have been made to limit voluntary control of sexual response during PPG assessments, without satisfactory results. This exploratory research examined eye-tracking technologies' ability to identify the presence of cognitive strategies responsible for erectile inhibition during PPG assessment. Eye movements and penile responses for 20 subjects were recorded while exploring animated human-like computer-generated stimuli in a virtual environment under three distinct viewing conditions: (a) the free visual exploration of a preferred sexual stimulus without erectile inhibition; (b) the viewing of a preferred sexual stimulus with erectile inhibition; and (c) the free visual exploration of a non-preferred sexual stimulus. Results suggest that attempts to control erectile responses generate specific eye-movement variations, characterized by a general deceleration of the exploration process and limited exploration of the erogenous zone. Findings indicate that recording eye movements can provide significant information on the presence of competing covert processes responsible for erectile inhibition. The use of eye-tracking technologies during PPG could therefore lead to improved internal validity of the plethysmographic procedure.     

Production and changeover control policies of a class of failure prone buffered flow-shops

This article deals with a stochastic optimal control problem for a class of buffered multi-parts flow-shops manufacturing system. The involved machines are subject to random breakdowns and repairs. The flow-shop under consideration is not completely flexible and hence requires setup time and cost in order to switch the production from a part type to another, this changeover is carried on the whole line. Our objective is to find the production plan and the sequence of setups that minimise the cost function, which penalises inventories/backlogs and setups. A continuous dynamic programming formulation of the problem is presented. Then, a numerical scheme is adopted to solve the obtained optimality conditions equations for a two buffered serial machines two parts case. A complete heuristic policy, based on the numerical observations which describe the optimal policies in system states, is developed. It will be shown that the obtained policy is a combination of a KANBAN/CONWIP and a modified hedging corridor policy. Moreover, based on our observations and existent research studies extension to cover more complex flow-shops is henceforth possible. The robustness of such a policy is illustrated through sensitivity analysis.     

Addressing potential prior‐data conflict when using informative priors in proof‐of‐concept studies

Bayesian methods are increasingly used in proof‐of‐concept studies. An important benefit of these methods is the potential to use informative priors, thereby reducing sample size. This is particularly relevant for treatment arms where there is a substantial amount of historical information such as placebo and active comparators. One issue with using an informative prior is the possibility of a mismatch between the informative prior and the observed data, referred to as prior‐data conflict. We focus on two methods for dealing with this: a testing approach and a mixture prior approach. The testing approach assesses prior‐data conflict by comparing the observed data to the prior predictive distribution and resorting to a non‐informative prior if prior‐data conflict is declared. The mixture prior approach uses a prior with a precise and diffuse component. We assess these approaches for the normal case via simulation and show they have some attractive features as compared with the standard one‐component informative prior. For example, when the discrepancy between the prior and the data is sufficiently marked, and intuitively, one feels less certain about the results, both the testing and mixture approaches typically yield wider posterior‐credible intervals than when there is no discrepancy. In contrast, when there is no discrepancy, the results of these approaches are typically similar to the standard approach. Whilst for any specific study, the operating characteristics of any selected approach should be assessed and agreed at the design stage; we believe these two approaches are each worthy of consideration. Copyright © 2015 John Wiley & Sons, Ltd.     

On smoothness of Tukey depth contours

The smoothness of Tukey depth contours is a regularity condition often encountered in asymptotic theory, among others. This condition ensures that the Tukey depth fully characterizes the underlying multivariate probability distribution. In this paper we demonstrate that this regularity condition is rarely satisfied. It is shown that even well-behaved probability distributions with symmetrical, smooth and (strictly) quasi-concave densities may have non-smooth Tukey depth contours, and that the smoothness behaviour of depth contours is fairly unpredictable.     

Personal income taxation under mobility, exogenous and endogenous welfare weights, and asymmetric information

This paper analyses how governments should tax labour income accruing to a group of highly skilled and geographically mobile individuals who divide their time or career between several jurisdictions. The analysis differs from previous models on migration and taxation by addressing optimal regulation when agents work for several principals. Optimal taxation is developed for social welfare functions with exogenous and endogenous welfare weights. Marginal income taxes are applied for screening purposes, and the rates are lower with endogenous than with exogenous welfare weights. Received: 22 January 1998/Accepted: 3 July 1999)     

Self-Reported Personal Well-Being of Youth Accessing Intensive Mental Health Treatment

Normative samples have been shown to rate their personal wellbeing (PWB) as positively high and high PWB is associated with many enduring benefits. Cummins (J Happiness Stud 10(6):1–17, 2009) has suggested that PWB has an equilibrium that is set at a rather high positive state and maintained through psychological mechanisms he termed homeostatic protected mood (HPM). Investigators who have explored PWB and mental health disorders have often focused on schizophrenia in adult populations, with varied results, and scant attention has been paid to clinical samples of youth with emotional and/or behavioral disorders. The purpose for this report was to explore the level of PWB reported by a subsample of youth who accessed residential treatment (n = 30) and intensive home based treatment (n = 33) at 12–18 months post-discharge, and explore whether clinical variables could predict PWB. Many youth reported high PWB despite experiencing continued challenges in symptoms and psychosocial functioning. Demographic and clinical characteristics did not predict participants’ PWB scores, lending support for the HPM theory with this sample of youth with emotional and behavioral disorder.