光谱法测量等离子体离子温度和再循环粒子流速

利用多道光学分析仪（OSMA）测量HT-6M托卡马克限制器前Hα线形分布,通过高斯拟合由多普勒展宽和多普勒频移分别得出等离子体离子温度和再循环粒子流速。     

对我国当前货币政策的分析

文章从理论依据和现实考察两方面分析货币政策的操作效果,并对今后我国货币政策的操作方向提出了若干建议.     

长三角科技资源配置能力与城市化进程的协调耦合关系研究

科技资源配置能力已成为长江地区城市化进程的重要推力。因此,在构建科技资源与城市化耦合系统评价指标体系的基础上,利用耦合协调度模型综合评价长江区域科技资源配置与城市化的交互耦合关系。结果显示:从时间维度看,研究期内长三角科技资源配置能力与城市化进程之间的耦合关系基本上处于磨合阶段,耦合协调度以低度协调耦合状态为主并逐步过渡到中度协调耦合状态;从空间维度看,长三角各城市的科技资源配置与城市化耦合协调度在极度协调耦合、高度协调耦合、中度协调耦合、低度协调耦合四个阶段均有分布,层级分明且大部分城市尚处于低度协调耦合状态。     

中国金融状况指数的构建及预测能力研究

本文首先选取利率、汇率、股票价格和社会融资规模四个金融变量,建立SVAR模型确定变量权重,构建了量化我国金融状况整体松紧程度的中国金融状况指数.其次,基于已构建指数,引入谱分析方法研究发现:中国金融状况指数与宏观经济景气指数中的一致指数、环比和同比CPI三个指标之间均存在39个月的耦合震荡周期,且中国金融状况指数领先三个指标的期数分别为1.91、0.44和5.5个月,对应一致性统计量的值依次为0.94、0.97和0.96,均接近于1,说明中国金融状况指数对宏观经济景气指数中的一致指数以及对通货膨胀均具有先导性和强相关性,可作为其他宏观经济指标的先行指标.     

An Efficient Estimation for Switching Regression Models: A Monte Carlo Study

This article investigates an efficient estimation method for a class of switching regressions based on the characteristic function (CF). We show that with the exponential weighting function, the CF-based estimator can be achieved from minimizing a closed form distance measure. Due to the availability of the analytical structure of the asymptotic covariance, an iterative estimation procedure is developed involving the minimization of a precision measure of the asymptotic covariance matrix. Numerical examples are illustrated via a set of Monte Carlo experiments examining the implementation, finite sample property and the efficiency of the proposed estimator.     

On the Preliminary Test Backfitting and Speckman Estimators in Partially Linear Models and Numerical Comparisons

Przystalski and Krajewski (2007 Przystalski , M. , Krajewski , P. ( 2007 ). Constrained estimators of treatment parameters in semiparametric models . Statist. Probab. Lett. 77 : 914 – 919 .[Crossref], [Web of Science ®] , [Google Scholar]) proposed the restricted backfitting (RBCF) estimator and restricted Speckman (RSPC) estimator for the treatment effects in a partially linear model when some additional exact linear restrictions are assumed to hold. In this article, we introduce the preliminary test backfitting (PTBCF) estimator and preliminary test Speckman (PTSPC) estimator when the validity of the restrictions is suspected. Performances of the proposed estimators are examined with respect to the mean squared error (MSE) criterion. In addition, numerical behaviors of the proposed estimators are illustrated and compared via a Monte Carlo simulation study.     

Case–control genome-wide joint association study using semiparametric empirical model and approximate Bayes factor

We propose a semiparametric approach for the analysis of case–control genome-wide association study. Parametric components are used to model both the conditional distribution of the case status given the covariates and the distribution of genotype counts, whereas the distribution of the covariates are modelled nonparametrically. This yields a direct and joint modelling of the case status, covariates and genotype counts, and gives a better understanding of the disease mechanism and results in more reliable conclusions. Side information, such as the disease prevalence, can be conveniently incorporated into the model by an empirical likelihood approach and leads to more efficient estimates and a powerful test in the detection of disease-associated SNPs. Profiling is used to eliminate a nuisance nonparametric component, and the resulting profile empirical likelihood estimates are shown to be consistent and asymptotically normal. For the hypothesis test on disease association, we apply the approximate Bayes factor (ABF) which is computationally simple and most desirable in genome-wide association studies where hundreds of thousands to a million genetic markers are tested. We treat the approximate Bayes factor as a hybrid Bayes factor which replaces the full data by the maximum likelihood estimates of the parameters of interest in the full model and derive it under a general setting. The deviation from Hardy–Weinberg Equilibrium (HWE) is also taken into account and the ABF for HWE using cases is shown to provide evidence of association between a disease and a genetic marker. Simulation studies and an application are further provided to illustrate the utility of the proposed methodology.     

Implementation of a Federated Search System: Resource Accessibility Issues

Abstract

During 2009, the Hilton M. Briggs Library, South Dakota State University, went live with MetaLib, a federated search engine from Ex Libris. This paper presents the implementation process, addresses resource accessibility issues, and suggests a number of resources that can be consulted about these issues. Readers can apply similar strategies to projects involving federated search systems, as many implementation projects involve the same basic considerations presented here. The author did not find any studies specifically focused on configurations of MetaLib resources, so this content should be singularly useful.     

Estimation of Main Effect When Covariates Have Non-Proportional Hazards

The Cox proportional hazards (PH) regression model has been widely used to analyze survival data in clinical trials and observational studies. In addition to estimating the main treatment or exposure group effect, it is common to adjust for additional covariates using the Cox model. It is well known that violation of the PH assumption can lead to estimates that are biased and difficult to interpret, and model checking has become a routine procedure. However, such checking might focus on the primary group comparisons, and the assumption can still be violated when adjusting for many of the potential covariates. We study the effect of violation of the PH assumption of the covariates on the estimation of the main group effect in the Cox model. The results are summarized in terms of the bias and the coverage properties of the confidence intervals. Overall in randomized clinical trials, the bias caused by misspecifying the PH assumption on the covariates is no more than 15% in absolute value regardless of sample size. In observational studies where the covariates are likely correlated with the group variable, however, the bias can be very severe. The coverage properties largely depend on sample size, as expected, as bias becomes dominating with increasing sample size. These findings should serve as cautionary notes when adjusting for potential confounders in observational studies, as the violation of PH assumption on the confounders can lead to erroneous results.     

Modeling of covariance structures of random effects and random errors in linear mixed models

Abstract

In this paper, we discuss how to model the mean and covariancestructures in linear mixed models (LMMs) simultaneously. We propose a data-driven method to modelcovariance structures of the random effects and random errors in the LMMs. Parameter estimation in the mean and covariances is considered by using EM algorithm, and standard errors of the parameter estimates are calculated through Louis’ (1982 Louis, T.A. (1982). Finding observed information using the EM algorithm. J. Royal Stat. Soc. B 44:98–130. [Google Scholar]) information principle. Kenward’s (1987 Kenward, M.G. (1987). A method for comparing profiles of repeated measurements. Appl. Stat. 36:296–308.[Crossref], [Web of Science ®] , [Google Scholar]) cattle data sets are analyzed for illustration,and comparison to the literature work is made through simulation studies. Our numerical analysis confirms the superiority of the proposed method to existing approaches in terms of Akaike information criterion.