Parallel sequential Monte Carlo for stochastic gradient-free nonconvex optimization

Statistics and Computing - We introduce and analyze a parallel sequential Monte Carlo methodology for the numerical solution of optimization problems that involve the minimization of a cost...     

From the employment office to the social welfare office: Social assistance recipiency among first-time unemployed in Sweden

Social assistance receipt among first-time unemployed in Sweden is investigated by analysing data files obtained by merging register data from the city of Goteborg. First-time unemployed males were observed during 1993 and 1994 and were followed in the register of social assistance recipients for 18 months after the debut. Many of the newly unemployed had no access to unemployment compensation. Slightly more than one out of five newly unemployed became social assistance recipients. Lengthy periods of unemployment combined with no access to unemployment compensation signify a high risk of becoming a social assistance recipient. This risk varies a great deal with age, citizenship, human capital and job search activity of the unemployed.     

A new modified Jackknifed estimator for the Poisson regression model

The Poisson regression is very popular in applied researches when analyzing the count data. However, multicollinearity problem arises for the Poisson regression model when the independent variables are highly intercorrelated. Shrinkage estimator is a commonly applied solution to the general problem caused by multicollinearity. Recently, the ridge regression (RR) estimators and some methods for estimating the ridge parameter k in the Poisson regression have been proposed. It has been found that some estimators are better than the commonly used maximum-likelihood (ML) estimator and some other RR estimators. In this study, the modified Jackknifed Poisson ridge regression (MJPR) estimator is proposed to remedy the multicollinearity. A simulation study and a real data example are provided to evaluate the performance of estimators. Both mean-squared error and the percentage relative error are considered as the performance criteria. The simulation study and the real data example results show that the proposed MJPR method outperforms the Poisson ridge regression, Jackknifed Poisson ridge regression and the ML in all of the different situations evaluated in this paper.     

Variability and Uncertainty in Swedish Exposure Factors for Use in Quantitative Exposure Assessments

Information of exposure factors used in quantitative risk assessments has previously been compiled and reported for U.S. and European populations. However, due to the advancement of science and knowledge, these reports are in continuous need of updating with new data. Equally important is the change over time of many exposure factors related to both physiological characteristics and human behavior. Body weight, skin surface, time use, and dietary habits are some of the most obvious examples covered here. A wealth of data is available from literature not primarily gathered for the purpose of risk assessment. Here we review a number of key exposure factors and compare these factors between northern Europe—here represented by Sweden—and the United States. Many previous compilations of exposure factor data focus on interindividual variability and variability between sexes and age groups, while uncertainty is mainly dealt with in a qualitative way. In this article variability is assessed along with uncertainty. As estimates of central tendency and interindividual variability, mean, standard deviation, skewness, kurtosis, and multiple percentiles were calculated, while uncertainty was characterized using 95% confidence intervals for these parameters. The presented statistics are appropriate for use in deterministic analyses using point estimates for each input parameter as well as in probabilistic assessments.     

Influence of Distribution of Animals between Dose Groups on Estimated Benchmark Dose and Animal Distress for Quantal Responses

Increasingly, dose‐response data are being evaluated with the benchmark dose (BMD) approach rather than by the less precise no‐observed‐adverse‐effect‐level (NOAEL) approach. However, the basis for designing animal experiments, using equally sized dose groups, is still primed for the NOAEL approach. The major objective here was to assess the impact of using dose groups of unequal size on both the quality of the BMD and overall animal distress. We examined study designs with a total number of 200 animals distributed in four dose groups employing quantal data generated by Monte Carlo simulations. Placing more animals at doses close to the targeted BMD provided an estimate of BMD that was slightly better than the standard design with equally sized dose groups. In situations involving a clear dose‐response, this translates into fewer animals receiving high doses and thus less overall animal distress. Accordingly, in connection with risk and safety assessment, animal distress can potentially be reduced by distributing the animals appropriately between dose groups without decreasing the quality of the information obtained.     

Description and Propagation of Uncertainty in Input Parameters in Environmental Fate Models

Today, chemical risk and safety assessments rely heavily on the estimation of environmental fate by models. The key compound‐related properties in such models describe partitioning and reactivity. Uncertainty in determining these properties can be separated into random and systematic (incompleteness) components, requiring different types of representation. Here, we evaluate two approaches that are suitable to treat also systematic errors, fuzzy arithmetic, and probability bounds analysis. When a best estimate (mode) and a range can be computed for an input parameter, then it is possible to characterize the uncertainty with a triangular fuzzy number (possibility distribution) or a corresponding probability box bound by two uniform distributions. We use a five‐compartment Level I fugacity model and reported empirical data from the literature for three well‐known environmental pollutants (benzene, pyrene, and DDT) as illustrative cases for this evaluation. Propagation of uncertainty by discrete probability calculus or interval arithmetic can be done at a low computational cost and gives maximum flexibility in applying different approaches. Our evaluation suggests that the difference between fuzzy arithmetic and probability bounds analysis is small, at least for this specific case. The fuzzy arithmetic approach can, however, be regarded as less conservative than probability bounds analysis if the assumption of independence is removed. Both approaches are sensitive to repeated parameters that may inflate the uncertainty estimate. Uncertainty described by probability boxes was therefore also propagated through the model by Monte Carlo simulation to show how this problem can be avoided.     

Computer support for continuous improvements

Abstract. The view of manufacturing has changed in recent years. This is evident from how the focus of management's attention is shifting more and more towards the basics of operating the business. The challenge to manufacturers in the West today is how to introduce leaner practices in their operations. The objective of this paper is to demonstrate how computer technology and information systems can be applied to support the transition to leaner practices in a complex operation. The problem with the large information systems developed to manage the complex operations of many Western companies is that they were designed to help maintain performance and not to support finding opportunities for new improved practices. Results from the ESPRIT II project, CIM for Multi-supplier Operations (CMSO), show that an existing data infrastructure can be effectively utilized to develop inexpensive, customized tools to support a process of continuous improvements. In this project a set of tools for planning the material flow from supplier to the assembly line was developed for the Saab-Valmet automobile assembly plant in Uusikaupunki, Finland. Hypertext tools were used to quickly develop decision support applications that supported problem solving and finding improvement potentials.