New Developments in Statistical Computing: New Bias Evaluation Features of EXPLOR—A Program for Assessing Experimental Design Properties

Longitudinal investigations play an increasingly prominent role in biomedical research. Much of the literature on specifying and fitting linear models for serial measurements uses methods based on the standard multivariate linear model. This article proposes a more flexible approach that permits specification of the expected response as an arbitrary linear function of fixed and time-varying covariates so that mean-value functions can be derived from subject matter considerations rather than methodological constraints. Three families of models for the covariance function are discussed: multivariate, autoregressive, and random effects. Illustrations demonstrate the flexibility and utility of the proposed approach to longitudinal analysis.     

Extensions of Samuelson's Inequality

In this note we obtain upper and lower bounds for the kth largest number in a set of real numbers in terms of their mean and standard deviation. For each inequality necessary and sufficient conditions for equality are given.     

Two Pitfalls of Using Standard Regression Diagnostics When Both X and Y Have Measurement Error

Modern exploratory data analysis produces models that are not based on physical theory but that are consistent with pictures of the data. When both X and Y have error this can be risky, because important features are hidden. Two examples are given that show that systematic model departures and heteroscedasticity may not be detectable with standard regression diagnostics.     

A Recursive Formula for the Probability of Occurrence of at Least m out of N Events

A recursive same-sign relation is derived that reduces the probability of occurrence of at least m out of N independent events to the probability of occurrence of at least m out of N ? 1 of these N events.     

An Improved Boxplot for Univariate Data

The boxplot is an effective data-visualization tool useful in diverse applications and disciplines. Although more sophisticated graphical methods exist, the boxplot remains relevant due to its simplicity, interpretability, and usefulness, even in the age of big data. This article highlights the origins and developments of the boxplot that is now widely viewed as an industry standard as well as its inherent limitations when dealing with data from skewed distributions, particularly when detecting outliers. The proposed Ratio-Skewed boxplot is shown to be practical and suitable for outlier labeling across several parametric distributions.     

The modified permutation entropy-based independence test of time series

Abstract

In time series, it is essential to check the independence of data by means of a proper method or an appropriate statistical test before any further analysis. Therefore, among different independence tests, a powerful and productive test has been introduced by Matilla-García and Marín via m-dimensional vectorial process, in which the value of the process at time t includes m-histories of the primary process. However, this method causes a dependency for the vectors even when the independence assumption of random variables is considered. Considering this dependency, a modified test is obtained in this article through presenting a new asymptotic distribution based on weighted chi-square random variables. Also, some other alterations to the test have been made via bootstrap method and by controlling the overlap. Compared with the primary test, it is obtained that not only the modified test is more accurate but also, it possesses higher power.